1,720,955 research outputs found
Structure of a novel exopolysaccharide produced by Burkholderia vietnamiensis, a cystic fibrosis opportunistic pathogen
No full textBurkholderia vietnamiensis belongs to the Burkholderia cepacia complex and is an opportunistic pathogen
for cystic fibrosis patients. As many other Burkholderia species, it has a mucoide phenotype, producing
abundant exopolysaccharide. In general, polysaccharides contribute to bacterial survival in a hostile
environment, are recognised as virulence factors and as important components in biofilm formation.
The primary structure of the exopolysaccharide produced by B. vietnamiensis LMG 10929 was determined
mainly by use of 1D and 2D NMR spectroscopy and ESI mass spectrometry. The polymer consists
of the trisaccharidic backbone 3)-beta-D-Glcp-(1→4)-alfa-D-Glcp-(1→3)-alfa-L-Fucp-(1→
with the side chain
alfa-D-Glcp-(1→4)-alfa-D-GlcAp-(1→3)-alfa-L-Fucp-(1→
linked to C-3 of the alfa-D-Glcp residue. The polysaccharide
also bears acetyl substituents on about 20% of its repeating units and on at least two different
positions. The presence of fucose residues is a novel structural feature among the exopolysaccharides
produced by species of the B. cepacia complex
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Investigation of bacterial resistance to the immune system response: Cepacian depolymerisation by reactive oxygenspecies.
No full textReactive oxygen species (ROS) are part of the weapons used by the immune system to kill and degrade infecting
microorganisms. Bacteria can produce macromolecules, such as polysaccharides, that are able to scavenge ROS.
Species belonging to the Burkholderia cepacia complex are involved in serious lung infection in cystic fibrosis patients
and produce a characteristic polysaccharide, cepacian. The interaction between ROS and bacterial polysaccharides was
first investigated by killing experiments, where bacteria cells were incubated with sodium hypochlorite (NaClO) with and
without prior incubation with cepacian. The results showed that the polysaccharide had a protective effect towards
bacterial cells. Cepacian was then treated with different concentrations of NaClO and the course of reactions was
followed by means of capillary viscometry. The degradation products were characterised by size-exclusion chromatography,
NMR and mass spectrometry. The results showed that hypochlorite depolymerised cepacian, removed side chains
and O-acetyl groups, but did not cleave the glycosidic bond between glucuronic acid and rhamnose. The structure of
some oligomers produced by NaClO oxidation is reported
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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