142 research outputs found
The Best of Both Worlds: Building on the COPUS and RTOP Observation Protocols to Easily and Reliably Measure Various Levels of Reformed Instructional Practice
No full textResearchers, university administrators, and faculty members are increasingly interested in measuring and describing instructional practices provided in science, technology, engineering, and mathematics (STEM) courses at the college level. Specifically, there is keen interest in comparing instructional practices between courses, monitoring changes over time, and mapping observed practices to research-based teaching. While increasingly common observation protocols (Reformed Teaching Observation Protocol [RTOP] and Classroom Observation Protocol in Undergraduate STEM [COPUS]) at the postsecondary level help achieve some of these goals, they also suffer from weaknesses that limit their applicability. In this study, we leverage the strengths of these protocols to provide an easy method that enables the reliable and valid characterization of instructional practices. This method was developed empirically via a cluster analysis using observations of 269 individual class periods, corresponding to 73 different faculty members, 28 different research-intensive institutions, and various STEM disciplines. Ten clusters, called COPUS profiles, emerged from this analysis; they represent the most common types of instructional practices enacted in the classrooms observed for this study. RTOP scores were used to validate the alignment of the 10 COPUS profiles with reformed teaching. Herein, we present a detailed description of the cluster analysis method, the COPUS profiles, and the distribution of the COPUS profiles across various STEM courses at research-intensive universities
Comparison of intravascular ultrasound assessment of segmental coronary vasomotor responses with Quantitative coronary angiography
No full textConference abstracts published as Supplement: Heart, Lung and Circulation, 2010; 19 (Supp. 2):S24R. Puri, G. Liew, A. Nelson, R. Das, D. Wong, A. Carbone, B. Copus, S. Nicholls, J. Beltrame, S. Worthley and M. Worthleyhttp://www.csanz2010.com
Sub-National Governance in England
No full textThis discussion is concerned with sub-national governance in England. It will suggest that the most striking characteristic of English sub-national governance is its fragmentary and incoherent nature, embracing regions (if they can still be said to exist), city-regions (which are subject to a number of different definitions) and local government (which itself is sub-divided from place to place into metropolitan, non-metropolitan, unitary and two-tier systems, with a range of differing political management arrangements). This pattern of sub-national provision has grown ever-more varied, subject to ad hoc initiatives, and with no overall rationale. It will be argued that - in contrast to other parts of the United Kingdom - there is currently no political incentive to address the nature of
English sub-national governance. Hence there is little likelihood that the pattern of governance depicted here will change, unless new factors are brought into play. Some of these are suggested at the end of this paper
Coronary atheroma composition predicts endothelial dysfunction in non-ST segment myocardial infarction: novel insights with radiofrequency (iMAP) intravascular ultrasonography (IVUS)
No full textPoster abstract TCT-648Abstract not availableRishi Puri, Stephen J. Nicholls, Danielle M. Brennan, Jordan Andrews, Gary Y. Liew, Angelo Carbone, Barbara Copus, Adam J. Nelson, Samir R. Kapadia, E. Murat Tuzcu, John F. Beltrame, Stephen G. Worthley, Matthew I. Worthle
Variations in coronary lumen dimensions measured In vivo
No full textLetter to the EditorRishi Puri, Adam J. Nelson, Gary Y. H. Liew, Stephen J. Nicholls, Angelo Carbone, Dennis T. L. Wong, James E. Harvey, Kiyoko Uno, Barbara Copus, Darryl P. Leong, John F. Beltrame, Stephen G. Worthley, Matthew I. Worthle
Praecepta salubria
No full textGuilielmo Copo Basileiensi interpreteImpressum gemäss Kolophon, Bl. g₄ rectoBogensignaturen: a⁴, b⁸, c⁴, d⁸, e⁴, f⁸, g⁴Titelholzschnitt; Holzschnittinitiale
Coronary beta(2)-adrenoreceptors mediate endothelium-dependent vasoreactivity in humans: novel insights from an in vivo intravascular ultrasound study
No full textAimsThe interaction between coronary β(2)-adrenoreceptors and segmental plaque burden is complex and poorly understood in humans. We aimed to validate intracoronary (IC) salbutamol as a novel endothelium-dependent vasodilator utilizing intravascular ultrasound (IVUS), and thus assess relationships between coronary β(2)-adrenoreceptors, regional plaque burden and segmental endothelial function.Methods and resultsIn 29 patients with near-normal coronary angiograms, IVUS-upon-Doppler Flowire imaging protocols were performed. Protocol 1: incremental IC salbutamol (0.15, 0.30, 0.60 μg/min) infusions (15 patients, 103 segments); protocol 2: salbutamol (0.30 μg/min) infusion before and after IC administration of N(G)-monomethyl-L-arginine (L-NMMA) (10 patients, 82 segments). Vehicle infusions (IC dextrose) were performed in 4 patients (21 segments). Macrovascular response [% change segmental lumen volume (ΔSLV)] and plaque burden [per cent atheroma volume (PAV)] were studied in 5-mm coronary segments. Microvascular response [per cent change in coronary blood flow (ΔCBF)] was calculated following each infusion. Intracoronary salbutamol demonstrated significant dose-response ΔSLV and ΔCBF from baseline, respectively (0.15 μg/min: 3.5 ± 1.3%, 28 ± 14%, P = 0.04, P = NS; 0.30 μg/min: 5.5 ± 1.4%, 54 ± 17%, P = 0.001, P < 0.0001; 0.60 μg/min: 4.8 ± 1.6%, 66 ± 15%, P = 0.02, P < 0.0001), with ΔSLV responses further exemplified in low vs. high plaque burden groups. Salbutamol vasomotor responses were suppressed by l-NMMA, supporting nitric oxide-dependent mechanisms. Vehicle infusions resulted in no significant ΔSLV or ΔCBF. Multivariate analysis including conventional cardiovascular risk factors, PAV, segmental remodelling and plaque eccentricity indices identified PAV as the only significant predictor of a ΔSLV to IC salbutamol (coefficient -0.18, 95% CI -0.32 to -0.044, P = 0.015). Conclusions Intracoronary salbutamol is a novel endothelium-dependent epicardial and microvascular coronary vasodilator. Intravascular ultrasound-derived regional plaque burden is a major determinant of segmental coronary endothelial function.Rishi Puri, Gary Y.H. Liew, Stephen J. Nicholls, Adam J. Nelson, Darryl P. Leong, Angelo Carbone, Barbara Copus, Dennis T.L. Wong, John F. Beltrame, Stephen G. Worthley, and Matthew I. Worthle
The introduction of a model of statistical data matrices encompassing original variate population methodologies
No full textPurpose: The purpose of this study was to examine the history, rationale, and sources of confusion of existing models and definitions of two and three dimensional statistical data matrices, and to lay a foundation for the acceptance of a standard model by suggesting clear definitions, recommendations, and modifications for a more robust model of statistical data matrices. Methods: The methodology used was documentary research concerning statistical data matrix models, an insight into the problems of these, and innovation in the introduction of a modified model. Findings: 1. A major source of confusion in the field of data matrices is the lack of standard definitions for basic concepts. 2. A major cause of the lack of standard definitions of data matrices was a transition in the definition of Q technique by its strongest proponent, William Stephenson, and his failure to acknowledge this transition.
(a) The lack of a standard definition of Q contributed to the controversy of whether or not R technique and Q technique may exist in one and the same matrix. By using Stephenson’s original definition of Q, R and Q may exist in the same matrix; by using Stephenson’s revised definition of Q, restricting Q to a population of statements, R and Q may not exist in the same matrix. (b) Although Stephenson claimed to have divided the six techniques of Raymond Cattell into two methodologies, the properties of the techniques were not consistent within each methodology. Stephenson’s revised definition of Q contributed to the inconsistencies of the properties between the technique within each methodology. 3. Stephenson’s transition was precipitated by the reciprocity principle of Sir Cyril Burt. 4. Measurement scales may be unique to a variate or common at least two variates. 5. In terms of Cattell’s techniques four equivalent descriptions exist for any re-standardization. Recommendations: 1. Cattell’s six techniques should be divided into three methodologies grouped according to the dimension of the original variate population sampled. The three original methodologies were designated as follows: (a) PPV- - the statistical analysis of person population variates; (b) APV- - the statistical analysis of attribute population variates; and (c) OPV- - the statistical analysis of occasion population variates, respectively. 2. The basis of each methodology would not be the two variates of analysis, as in Cattell’s techniques, but rather the population of the individual original variate. 3. The properties of measurement scale, conduciveness to a Sort, and population are consistent within each population methodology. 4. Different population methodologies may exist in the same matrix without re-standardization if common scaling exists through each dimension. 5. Although in terms of Cattell’s techniques four equivalent descriptions exist for any re-standardization, a re-standardization can be expressed in but one manner in the original population model. 6. Re-standardization should be clearly distinguished in terms of its original and resulting variate populations. 7. In the case of an APV Sort, an additional axis was found necessary for the population of instructions. An additional designation, IPV, the statistical analysis of instruction population variates, can only be the result of re-standardization from a previous APV Sort
Farmer and Rancher Suicide Prevention Posters
No full textTo develop a poster for farmer and rancher suicide awareness, the author first researched general suicide prevention and awareness posters to see analyze successful examples and to get ideas for potential themes, colors, and content. The ideas generated in this process needed to be methodically applied to make the content relevant and relatable for those in the agricultural industry. In this process, the author chose to incorporate a word cloud filled with words that represent agricultural issues and influence farmer and rancher suicide. The phrase “Suicide does not solve agricultural issues,” was chosen to use as the title at the top of the poster. This phrase is relevant when distributed through agricultural organizations because those organizations are responsible for working with farmers and ranchers to develop solutions for agricultural issues, including the issues listed in the word cloud
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