284 research outputs found
Ismerte-e Laskai Osvát Anonymus gesztáját? : Reflexiók a Magyar Könyvszemlében megjelent három dolgozatra = Was Osvat de Lasko familiar with the gesta of Anonymus? : Reflections on three essays published in the Magyar Könyvszemle
No full textThe author gives a definite “NO” answer to the question raised in the title of the study. He examines in depth three former publications written by the same person published in the 2004 and the next two volumes of Magyar Könyvszemle representing an opposite view. The author refuses several statements formulated in these papers, particularly those trying to justify that Franciscan friar and preacher Osvat de Lasko (≈1450–1511) was familiar with the gesta written in the early 13th century by Hungarian historian widely known as Anonymus. According to the author's analysis the use of certain expressions constituting the basis for such an hypothesis can be explained easily by referring to Osvat's well-known other sources. The author refuses other statements of these papers too, including the possible use of the so called Kézai-chronicle by Osvat de Lasko
“Quodam frater hungarus ordinis minorum de observantia”. Osualdus de Lasko’s Identity as a Preacher and Author of Sermons
No full textOsualdus de Lasko (OFM Obs, ca. 1450–1511) composed two sermon collections, which were published in print at the end of the fifteenth and the beginning of the sixteenth centuries. However, the readers of his books did not know the name of the author, who was only introduced as “quodam frater hungarus ordinis minorum de observantia”. This paper considers this option for anonymity as a premise for further investigating Osualdus’ identity as an author of sermons and as a preacher, intending to answer questions such as: How is Osualdus presenting or representing himself as an author/preacher? For what reasons and purpose did he compile these sermon collections? How were his homiletic works related to real preaching? Which was his ideal of a preacher? How relevant are the Franciscan affiliation and Hungarian origins for his identity? Grounded on the idea that the author is embedded in his text, this essay explores the prologues of Osualdus’ works and three of his sermons that discuss precisely about preaching’s agents, role, and beneficiaries. The analysis emphasizes that Osvalus’ vision of the ideal preacher and self-representation as author of sermons is shaped by Franciscan concepts of humility, renunciation and imitatio Christi.
Anonymity is also presented as a possible sign of humbleness, in the spirit of Franciscan values. Similarly, his understanding of the goal of spreading the Word of God follows the mission of the Friars Minor in general, and their actions in Hungary in particular: fighting heterodox beliefs, converting heretics and schismatic, defending and strengthening faith at the margins of Christendom. Osualdus’ concern for the catechization of simple people might have also been a consequence of the local experience of Franciscans and their contact with the peasantry in their rural convents. The paper concludes that in Osualdus’ case anonymity is not intended to hide or disguise his identity, which is clearly defined around the two elements used as a signature: the Hungarian origins and the Franciscan affiliation. His authority as a preacher and author of sermons resided in his special commission as a member of the Order of Friars Minor and his messages were mainly intended for the local public and for the safeguard of his homeland. The name of the author/preacher was most probably known to his primary audience. Only for the distant readers of his texts the author became anonymous, but they were made aware of the essential components of its identity, representative for the content as well
(A and B) In mosaics, loss of causes incompletely penetrant defects in epithelial structure, causing egg chamber fusion (A) and follicle cell multilayering, which mainly affects clones positioned at the anterior or posterior poles of the egg chamber (B)
No full text(C and C′) Two partial projections from a single optical stack though a mosaic late stage oocyte. mutant follicle cells are marked by lack of GFP (green) and lack of RanBPM (blue), and nuclei are labeled with DAPI (red). An extended dorsal appendage (arrow) is surrounded by wild-type cells in C, whereas on the other side of the embryo (C′), mutant cells surround a short, paddle-like dorsal appendage (arrow). (D) Homozygotes for the hypomorphic allele are fertile and have normal egg chamber morphology except for an incompletely penetrant defect in oocyte nuclear positioning. The normal posterior position of the oocyte is marked with an arrowhead, and the ectopic position is marked with an arrow. (E and F) The phenotype of is normal except for an oocyte localization defect, but a dominant enhancement after removing one copy of causes egg chamber fusion (E) and loss of epithelial integrity (F). Bars, 25 μm.<p><b>Copyright information:</b></p><p>Taken from "RanBPM regulates cell shape, arrangement, and capacity of the female germline stem cell niche in "</p><p></p><p>The Journal of Cell Biology 2008;182(5):963-977.</p><p>Published online 8 Sep 2008</p><p>PMCID:PMC2528568.</p><p></p
Stochastic variation: From single cells to superorganisms
No full textObserved phenotype often fails to correspond with genotype. Although it is well established that uncontrolled genetic modifier effects and environmental variability can affect phenotype, stochastic variation in gene expression can also contribute to phenotypic differences. Here we examine recent work that has provided insights into how fundamental physical properties of living cells, and the probabilistic nature of the chemical reactions that underlie gene expression, introduce noise. We focus on instances in which a stochastic decision initiates an event in the development of a multicellular organism and how that decision can be subsequently fixed. We present an example indicating that a similar interplay between an initial stochastic decision and subsequent fixation may underlie the regulation of reproduction in social insects. We argue, therefore, that stochasticity affects biological processes from the single‐gene scale through to the complex organization of an ant colony, and represents a largely neglected component of phenotypic variation and evolution
Event-related potentials to auditory stimuli in monozygotic twins discordant for combat: Association with PTSD
No full textStudies have demonstrated ERP abnormalities related to concentration difficulties in post-traumatic stress disorder (PTSD). We used an identical-twin, case-control design to investigate whether these abnormalities reflect pre-trauma vulnerability or the acquired consequence of PTSD. Vietnam combat veterans and their non-combat-exposed, identical twins completed a three-tone oddball task. Veterans with PTSD had delayed target N2 latencies compared to veterans without PTSD. In a small nonmedicated, nonsmoking subsample, veterans with PTSD also had significantly diminished target P3b amplitudes. A mixed-model, random-effects analysis on the nonmedicated, nonsmoking subsample that included the combat-unexposed co-twins showed a significant Diagnosis x Combat Exposure interaction for target P3b amplitude. Results replicate increased N2 latency and diminished P3b amplitude in PTSD and suggest that diminished P3b amplitude is an acquired condition in PTSD.Linda J. Metzger, C. Richard Clark, Alexander C. Mcfarlane, Melinda D. Veltmeyer, Natasha B. Lasko, Stephen R. Paige, Roger K. Pitman and Scott P. Or
Fair Wages and Employment for the Physically and Mentally Disabled
No full textSpring 2016Accompanied by video fil
Functional genomics : analysis of polytene region 38 of Drosophila melanogaster
No full textThis thesis reports the results of genetic and molecular analysis of polytene region 38 of D. melanogaster.A detailed genetic map of the region has been constructed through the complementation analysis of 22 genes with 37 deficiency stocks, providing 48 breakpoints. 44 of the breakpoints have been precisely mapped and separate the complementation groups into 16 distinct intervals.Molecular characterisation was achieved using a combination of computational sequence analysis and experimental techniques. In this manner, 46 new transcription units and their developmental expression patterns were identified and the physical location of 7 deficiency breakpoints revealed. Links have been established between the genetic and the physical maps using STSs and sequence information from previously cloned genes. This allowed the possible correlation of 4 previously genetically defined genes to their transcription units
1994-1995 SAR resident scholars
No full textGroup portrait of resident scholars at the School of American Research during their 1994-95 fellowships. Back row: Andre Gingrich, Christopher B. Steiner. Middle row: Gil J. Stein, Jill L. Furst, Vernon L. Scarborough. Seated: Marisol de la Cadena
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