993 research outputs found
Distributed PC Based Routers: Bottleneck Analysis and Architecture Proposal
No full textRecent research in the different functional areas of modern routers have made proposals that can greatly increase the efficiency of these machines. Most of these proposals can be implemented quickly and often efficiently in software. We wish to use personal computers as forwarders in a network to utilize the advances made by researchers. We therefore examine the ability of a personal computer to act as a router. We analyze the performance of a single general purpose computer and show that I/O is the primary bottleneck. We then study the performance of distributed router composed of multiple general purpose computers. We study the performance of a star topology and through experimental results we show that although its performance is good, it lacks flexibility in its design. We compare it with a multistage architecture. We conclude with a proposal for an architecture that provides us with a forwarder that is both flexible and scalable.© IEE
Chemoselective reaction of indole 1,3-dicarboxylates towards hydrazine hydrate: Bisheterocycles: Synthesis and antimicrobial activity of some new 2-methyl-3-ethoxycarbonyl-1-oxadiazolyl/thiazolidinonyl/pyrrolylaminocarbonylmethylindoles
No full text1663-1668Chemoselectivity
of 1-ester over C3-ester of the indole dicarboxylates 3a,b towards the nucleophilic attack of
hydrazine hydrate has been evidenced by the exclusive formation of
1-hydrazinocarbonylmethyl-3-ethoxycarbonyl-5-substituted-2-methylindoles 5a,b which have been further reacted
separately with CS2/KOH, p-chlorobenzaldehyde and acetonyl
acetone to furnish the 1-(5-mercapto-1,3,4-oxadiazol-2-yl)methyl-3-ethoxycarbonyl-5-substituted-2-methylindoles
6a,b, 1-p-Chlorobenzylidenehydrazinocarbonylmethyl-3-ethoxycarbonyl-5-substituted-2-methylindoles
7a,b and 1-(2,5-dimethylpyrrol-1-yl)aminocarbonylmethyl-3-ethoxycarbonyl-5-substituted-2-methylindoles
8a,b respectively. The Schiff’s bases 7a,b are reacted separately with thioglycolic acid to get the
desired 1-(2-p-chlorophenyl-4-thiazolidinon-1-yl)aminocarbonylmethyl-3-ethoxycarbonyl-5-substituted-2-methylindoles
9a,b. These newly synthesised
compounds are screened for their antibacterial and antifungal activities
Studies on carbohydrate moieties of the glycoprotein, glucoamylase II of Aspergillus niger: nature of carbohydrate-peptide linkage and structure of oligosaccharides
No full textElectrophoretically homogeneous type 1 (GP-C1 and GP-C2), type 2 (GP-C3a and GP-C3b,) and type 3 (GP-D1, and GP-D2) glycopeptides from Aspergillus niger glucoamylase II (Manjunath and Raghavendra Rao, preceding paper) were separately treated with alkaline borohydride. The (β-eliminated oligosaccharides were subjected to single and sequential digestion with specific glycosidases and the products analysed by gas liquid chromatography. The studies revealed that carbohydrate moieties were present as mannose, Man-Man-, and trisaccharide structures, namely, (a) GIc-Man-Man-, (b) Gal-Man-Man, (c) Man-Man-Man-, (d) GlcNAc-Man-Man-, and (e) Xyl-Man-Man. None of the glycopeptides contained all the trisaccharide structures (a) to (e). Type 1 glycopeptide contained structures (a), (b) and (c); type 2, (a) and (d) and type 3, (a), (b) and (e). The number of carbohydrate units (mono-, di-and trisaccharides) present in the major glycopeptides was determined and tentative structures for the glycopeptides proposed. Carbohydrate units appeared to occur in clusters of 4 to 7 in each glycopeptide, a structure unique to the carbohydrate moiety in Aspergillus niger glucoamylase. Based on carbohydrate analysis and yields of glycopeptide, the number of units of each type of glycopeptide present in glucoamylase II was tentatively calculated to give two of type Man:Glc:Gal = 12-15:l:l, one of type Man:Glc:GlcN = 10-l1:1:2 and one of type Man :GIc :Gal:Xyl = 4-8:0.1:0.5-0.8:0.3-1 glycopeptides
Scientometric Portrait of Homi Jehangir Bhabha: The Father of Indian Nuclear Research Programme
No full textQuantitative and qualitative analysis with graphic representation of the publication productivity of a scientist facilitates easy and clear perception about the work of a scientist. Bhabha’s scientific work spanned over more than three decades (1933-1967) during which he published 104 publications, which could be classified into nine fields: Interaction of Radiation with Matter (4), Quantum Electrodynamics (5), Mathematical Physics (2), Cosmic Ray Physics (18), Elementary Particle Physics (14), Field Theory (15), General Physics (2), Nuclear Physics (4) and General (40). The highest number of publications (6) were published in 1941, 1945 and 1964 respectively. The average number of publications published per year was 3.05. His productivity coefficient was 0.05 which is a clear indicates that his publication productivity was quite consistent throughout his scientific career. He was single author in 79 of his publications and the main author in 24 publications indicates that he always preferred to work himself and lead the team as ‘mentor’. Bhabha had 22 collaborators during the period. Team of research collaborators working with a successful scientist documents the sociological aspect of history of science while generating knowledge by a leader in a domain.
Bhabha became a citable author in 1937. Bhabha received 1211 citations to his 30 publications out of 104 publications. Out of 104, 74 publications did not receive any citations. Out of 74 publications, 40 publications dealt subjects mainly of general interest. Bhabha’s 86.66 percent of cited publications received their first citations within four years of their publication indicates that his publications were noticed immediately and had direct impact among the fellow researchers working all over the world. His overall citation rate was 11.64 per cited publication. The highest citations 389 were received to the domain ‘Cosmic ray physics’. The highest number of citations received were 45 in 1938. His self-citations were only 24 (1.98%) and citations by others were 1187 (98.02%). The highest self citations were six in 1946. Bhabha’s mean diachronous self-citation rate was 1.98. The highest citation rate 28.4 was to the domain ‘Quantum electrodynamics. His single authored publications have received the highest number 863 (71.26%) of citations. Bhabha’s five publications have been cited more than 100 times each. His publications have been cited by the authors working in various diverse fields like nuclear physics, mathematical physics, instrumentation, optics, geophysics and geochemistry, condensed matter physics, applied physics, electrical and electronic engineering, mechanical engineering etc., indicating a very diverse influence and impact of Bhabha’s publications. Bhabha’s publications have also been cited by the Nobel laureates like V. L. Ginzberg, Wolfgang Pauli, H. A. Bethe, M. Born, W. Bothe, E. P. Wigner, H. Yukawa, P. M. S. Blackett and C. N. Yang which is an indication of his originality of ideas and high quality of publications
Chemoselective reaction of benz[<i>g</i>]indole dicarboxylate towards hydrazine hydrate: Bisheterocycles: Synthesis and antimicrobial activity of some new 1-[2-hydroxyethyl]-3-ethoxycarbonyl-5-oxadiazolyl/triazolyl/ pyrrolylaminocarbonylmethoxy-2-methylbenz[<i>g</i>]indoles
No full text794-800The exclusive formation of
1-[2-hydroxyethyl]-3-ethoxycarbonyl-2-methyl benz[g] indol-5-yloxyacetic
acid hydrazide 6 from
1-[2-hydroxyethyl]-3-ethoxycarbonyl-5-methoxycarbonylmethoxy-2-methylbenz[g]indole 3 revealed
the chemoselectivity of the C5-ester over C3-ester
towards nucleophilic attack of hydrazine hydrate. This monocarbohydrazide 6 is reacted separately with CS2/KOH,
acetonyl acetone and isothiocyanates to secure the desired 1-[2-hydroxyethyl]-3-ethoxycarbonyl-5-(5-mercapto-1,3,4,-oxadiazl-2-y1)methoxy-2-methylbenz[g]indole 7,
1-[2-hydroxyethyl]-3-ethoxy-carbonyl-5-(2,5-dimethylpyrrol-1-yl)aminocarbonylmethoxy-2-methylbenz[g]indole
8 and 1-[2-hydroxyethyl]-3-ethoxycarbonyl-5-(N-substituted
thiosemicarbazinocarbonyl)methoxy-2-methylbenz[g]indole 9a-c. These thiosemicarbazides 9a-c are reacted with 4% NaOH to
produce the 1-[2-hydroxyethyl]2-methybenz[g]indol-5-(4-substituted-5-mercapto-1,2,4-triazol-3-yl)methoxy-3-caboxylic
acids 10a-c. All theses newly
synthsised compounds are screened for their antimicrobial activities
Atherogenic dyslipidemia
No full textAtherogenic dyslipidemia (AD) refers to elevated levels of triglycerides (TG) and small-dense low-density lipoprotein and low levels of high-density lipoprotein cholesterol (HDL-C). In addition, elevated levels of large TG rich very low-density lipoproteins, apolipoprotein B and oxidised low-density lipoprotein (LDL), and reduced levels of small high-density lipoproteins plays a critical role in AD. All three elements of AD per se have been recognised as independent risk factor for cardiovascular disease. LDL-C/HDL-C ratio has shown excellent risk prediction of coronary heart disease than either of the two risk markers. Asian Indians have a higher prevalence of AD than western population due to higher physical inactivity, low exercise and diet deficient in polyunsaturated fatty acids (PUFA). The AD can be well managed by therapeutic lifestyle changes with increased physical activities, regular exercise, and diets low in carbohydrates and high in PUFA such as omega-3-fatty acids, as the primary intervention. This can be supplemented drug therapies such as statin monotherapy or combination therapy with niacin/fibrates. Rosuvastatin is the only statin, presently available, to effectively treat AD in diabetes and MS patients
Synthesis, structural and ferromagnetic properties of La1-xKxMnO3 (0.0 <= x <= 0.25) phases by solution combustion method
No full textWe describe the solution combustion synthesis and characterization of La1-xKxMnO3 (0.0 <= x <= 0.25) perovskite phases, which is a low temperature initiated, rapid route to prepare metal oxides. As-synthesized compounds are amorphous in nature; crystallinity was observed on heating at 800 degrees C for 5 min. Structural parameters were determined by the Rietveld refinement method using powder XRD data. Parent LaMnO3 compound crystallizes in the orthorhombic structure (space group Pbnm, No. 62). Potassium substituted compounds were crystallized with rhombohedral symmetry (space group R-3c, No. 167). The ratio of the Mn3+/Mn4+ was determined by the iodometric titration. The Fourier transform infrared spectrum (FTIR) shows two absorption bands for Mn-O stretching vibration (v, mode), Mn-O-Mn deformation vibration (v(b) mode) around 600 cm(-1) and 400 cm(-1) for the compositions, x = 0.0, 0.05 and 0-10. Four-probe electrical resistivity measurements reveal a composition controlled metal to insulator transition (TM-1), the maximum TM-1 was observed for the composition La0.85K0.15MnO3 at 287 K. Room temperature vibrating sample magnetometer data indicate that for the composition up to x = 0-10, the compounds are paramagnetic whereas composition with x = 0.15, 0.20 and 0.25 show magnetic moments of 27, 29 and 30 emu/g, respectively
Abordagens melódico-vocais para exploração de novas possibilidades artísticas na bateria
No full textO presente trabalho trata abordagens melódicas e vocais aplicadas na bateria dentro do repertório jazz, desde a manipulação da altura dos sons ao estilo de Ari Hoenig, à orquestração de padrões rítmicos na estética do beatbox praticado por Tigran Hamasyan, e à aplicação de vocabulário rítmico vocal de B C Manjunath proveniente da música clássica do Sul da Índia.
No geral, a definição e aplicação de uma abordagem melódica é tão única como o instrumentista que opta por defini-la ou aplicá-la. Na atualidade, encontram-se três exemplos de referência em campos melódico-vocais distintos: i) o baterista norte-americano Ari Hoenig desenvolve uma abordagem de percussão melódica na bateria dentro do repertório jazz; ii) o pianista arménio Tigran Hamasyan incorpora sons de beatbox nas suas composições; e iii) o percussionista indiano B C Manjunath, enquanto intérprete de percussão vocal no estilo konakkol.
A metodologia que serve de base a este estudo divide-se em três etapas: recolha; interpretação e aplicação. A primeira etapa inclui a recolha de referências bibliográficas e audiovisuais relacionadas com os temas principais do trabalho, nomeadamente Ari Hoenig, Tigran Hamasyan e B C Manjunath, autores que suportam a análise.
A segunda etapa integra o tratamento e interpretação dos elementos recolhidos através da transcrição e construção de um repertório, desenvolvendo-se também modelos de notação musical específicos para cada abordagem. A terceira e última etapa consiste na
aplicação desse repertório à bateria, tanto ao nível solístico como ao nível coletivo com um conjunto variado de instrumentistas.
Este trabalho tem assim como propósito criar novas possibilidades performativas para a bateria e potenciar diferentes dinâmicas na relação com outros instrumentistas.The present work deals with melodic and vocal approaches applied to the drums within the jazz repertoire, from the manipulation of the pitch of sounds in the style of Ari Hoenig, to the orchestration of rhythmic patterns in the beatbox aesthetic practiced by Tigran
Hamasyan, and the application of B C Manjunath's vocal rhythmic vocabulary from South Indian classical music.
Overall, the definition and application of a melodic approach is as unique as the instrumentalist who chooses to define or apply it. Currently, there are three reference examples in distinct melodic-vocal fields: i) American drummer Ari Hoenig develops a melodic drumming approach within the jazz repertoire; ii) Armenian pianist Tigran Hamasyan incorporates beatbox sounds in his compositions; and iii) Indian percussionist B C Manjunath, as a performer of vocal percussion in the konakkol style.
The methodology that serves as the basis for this study is divided into three stages: collection; interpretation; and application. The first stage includes the collection of bibliographic and audiovisual references related to the main themes of the work, namely Ari Hoenig, Tigran Hamasyan, and B C Manjunath, authors who support the analysis. The second stage integrates the treatment and interpretation of the elements collected through the transcription and construction of a repertoire, also developing specific musical notation models for each approach. The third and final stage consists in the application of this repertoire to the drums, both solo and with a diverse ensemble of instrumentalists.
The purpose of this work is to create new performative possibilities for the drums and to enhance different dynamics in the relationship with other instrumentalists
1,3-Dipolar cycloaddition reactions: Synthesis and antimicrobial activity of novel 1-triazolylethylindole and 1-triazolylethylbenz[g]indole derivatives
No full text1068-1073Indole azide 4 and benz[g]indole azide 12
are reacted separately with dimethyl acetylenedicarboxylate to secure the
desired
1-[4,5-dimethoxycarbonyl-1,2,3-triazol-1-yl]ethyl-3-ethoxycarbonyl-5-methoxy-2-methylindole
5 and 1-[4,5-dimethoxycarbonyl-1,2,3-triazol-1-yl]ethyl-3-ethoxycarbonyl-5-methoxy-2-methylbenz[g]indole
13, respectively. The reaction of
indole azide 4 and benz[g]indole
azide 12 with ethyl propiolate has
been found to be regiospecific and produce only the
1-[4-ethoxycarbonyl-1,2,3-triazol-1-yl]ethyl-3-ethoxycarbonyl-5-methoxy-2-methylindole
6 and
1-[4-ethoxycarbonyl-1,2,3-triazol-1-yl]ethyl-3-ethoxycarbonyl-5-methoxy-2-methylbenz[g]indole
14, respectively. Indole azide 4 is also reacted with ethyl
phenylpropolate to secure two isomeric products
1-[4-ethoxycarbonyl-5-phenyl-1,2,3-triazol-1-yl]ethyl-3-ethoxycarbonyl-5-methoxy-2-methylindole
8 and
1-[4-phenyl-5-ethoxycarbonyl-1,2,3-triazol-1-yl]ethyl-3-ethoxycarbonyl-5-methoxy-2-methylindole
9. All these newly synthesised
compounds are screened for their antimicrobial activities
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