165 research outputs found
European Society of Gastrointestinal Endoscopy (ESGE) curricula development for postgraduate training in advanced endoscopic procedures: Rationale and methodology
No full textsponsorship: R. Bisschops is supported by the Research Foundation - Flanders (FWO). J. E. East was funded by the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre. The views expressed are those of the author(s) and not necessarily those of the National Health Service, the NIHR, or the Department of Health. (Research Foundation - Flanders (FWO) - National Institute for Health Research (NIHR) Oxford Biomedical Research Centre)status: Publishe
Infuences on real estate benchmarking practice: Understanding the challenges and opportunities in the real estate benchmarking process
No full textAccording to current theory, corporate real estate departments should choose a limited set of personalized Key Performance Indicators that are based on their own strategy and context. In general, organizations are often found to lack an objective assessment and rationale for the selection of these KPIs. Although previous studies have made an inventory of a large amount of possible performance indicators for real estate, still relatively little is known about what inluences the choice for certain indicators. In this study the factors that influence an organization to choose certain KPI’s to benchmark their real estate are uncovered. In order to do this, 22 interviews were conducted with a variety of experts and practitioners. As a general conclusion, it can be posited that two of the strongest influences that were found are the current financial crisis and the fact that CREM departments report to finance. These two factors both cause a strong focus on quantitative and especially financial KPI’s. However, what influences benchmarking practices above all is the fact that benchmarking is a very complex process, many challenges can be encountered along the way and producing truly meaningful results requires competence, experience and a well-structured process. Organizations, on average are found to have built still relatively little experience and competence in this area, only the most basic kpi’s are used as portfolio-wide benchmarks and the validity and completeness of these benchmarks is still low.Real Estate ManagementReal Estate & HousingArchitecture and The Built Environmen
Molecular responses of Saccharomyces cerevisiae to near-zero growth rates
No full textBiotechnologyApplied Science
Electric Vehicles; The Driving Power for Energy Transition: Blockchain-based Decentralised Energy Trading
No full textThe widespread introduction of (hybrid) electric vehicles has caused dynamic, local energy demand peaks. While, decentral energy generation, often using sustainable methods, creates local over-supply. Following the trends of the previous decade, the central balancing party (TenneT) will soon be no longer able to keep up. Blockchain offers an outcome by ruling out the third party and enabling direct sales from supply to demand. The technology offers a safe and transparent transaction platform. In collaboration with CGI Nederland a proof-of-concept is developed that proves the usefulness of the technology for a decentral, distributed, peer-to-peer energy trading system. In my thesis research I developed an algorithm that enables electricity trading between households and electric vehicles, benefiting both systems from an operator's perspective, as well as the individual system users.Civil Engineering and GeosciencesTransport & PlanningTransport, Infrastructure & Logistics (TIL
Preliminary design of multipurpose pilot plant for the recycling of polyurethane waste
No full textDocument uit de collectie Chemische ProcestechnologieDelftChemTechApplied Science
Abstract P4-02-08: Opto-acoustic imaging of the breast: Downclassification and upclassification of suspicious breast masses
No full textAbstract
Background
Imagio® is an opto-acoustic (OA) breast imaging system designed to concomitantly collect OA images together with diagnostic ultrasound (CDU). The device is intended to improve distinction between benign and malignant masses. In this interim analysis of the post-market surveillance MAESTRO study we report the results of 75 patients who had breast masses classified as BI-RADS 4a and 4b by CDU.
Aim
We assessed OA's sensitivity, specificity, and its ability to downgrade benign masses and upgrade malignant masses based on the probability of malignancy (POM) and BI-RADS category.
Methods
Seventy-five patients with 78 breast masses were evaluated with OA prior to biopsy. For each mass, the radiologist scored 5 OA features, assigned a POM and BI-RADS category. OA sensitivity, specificity, and BI-RADS downgrade and upgrade percentages were assessed with and without contribution from a previously derived nomogram.
Results
The mean POM difference between malignant and benign masses was higher for OA (37%) than for CDU (27%). OA specificity was 43% without the nomogram and 68% with the nomogram. OA sensitivity was 97% with and without the nomogram. With OA 43% of benign masses could be downgraded and 47% of malignant masses could be upgraded in BIRADS category.
Conclusion
These results appear to confirm the previously reported ability of OA to improve the differentiation between benign and malignant masses compared to CDU alone, to potentially decrease negative biopsies, and to upgrade BI-RADS category in malignant masses. The MAESTRO study (n=200) may further confirm these results.
Citation Format: Menezes GLG, Pijnappel RM, Meeuwis C, Bisschops B, Veltman J, Lavin PT, Mann RM. Opto-acoustic imaging of the breast: Downclassification and upclassification of suspicious breast masses [abstract]. In: Proceedings of the 2016 San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl):Abstract nr P4-02-08.</jats:p
The available pastor
No full textPastors are expected to serve other people. This article discusses the psychological factors that influence this capacity to be available. What makes it possible for people to set aside their own needs and to sense the needs and feelings of others? On the basis of psychological research and theories about this capacity to be available the author concludes that a truly available pastor first and foremost has to take care of his or her own needs
Is there a role for new imaging techniques in endoscopic surveillance?
No full textL’incidence de la dégénérescence néoplasique dans l’oesophage
de Barrett est en nette augmentation dans les pays occidentaux.
La surveillance endoscopique visant à détecter cette pathologie à
un stade précoce joue un rôle majeur dans la survie globale après
chirurgie. Grâce aux techniques nouvelles telles que la résection
endoscopique ou l’ablation par radiofréquence, maintenant disponibles
pour traiter la maladie de manière moins invasive, la détection
précoce de la dysplasie devient un enjeu de tout premier ordre.
Récemment, plusieurs procédés nouveaux ont été mis en oeuvre,
visant à une meilleure efficacité au niveau de la détection de la
dysplasie. Ce sont la chromoendoscopie classique, la chromo
endoscopie virtuelle, l’imagerie par auto-fluorescence et l’endomicroscopie
confocale. Parmi elles, l’imagerie par autofluorescence
semble la plus prometteuse en tant qu’outil d’alerte
alors que la chromoendoscopie virtuelle aide à caractériser les
lésions. L’endomicroscopie confocale permet une étude histologique
in vivo et aide à confirmer le diagnostic de lésions néoplasiques.
En règle générale, le rôle exact de ces nouveaux procédés
d’imagerie dans un programme général de détection n’a pas été
réellement envisagé, si bien qu’actuellement, le gold standard pour
la surveillance de l’oesophage de Barrett reste toujours l’endoscopie
haute définition en lumière blanche et le protocole de Seattle.The incidence of Barrett’s associated neoplasia is rising in the
Western world. Endoscopic surveillance in order to detect this
disease in an earlier stage has implication on overall survival after
surgery. With new techniques such as endoscopic resection or
radiofrequency ablation available now to treat the disease in a less
invasive way, early detection of dysplasia becomes even more
important. Recently several new imaging modalities have become
available with a possible improvement in efficiency for detecting
dysplasia. These include classical chromo-endoscopy, virtual
chromo-endoscopy, autofluorescence imaging and confocal endomicroscopy.
Of these autofluorescence imaging seems most promising
as a red flag technique, whereas (virtual) chromoendoscopy
helps to characterize lesions. Confocal endomicroscopy enables in
vivo histology and helps to confirm neoplastic lesions. In general, the
exact role of these new imaging modalities in a general screening
program has not been addressed, so currently a thorough inspection
with white light high definition endoscopy and the Seattle
protocol are still the gold standard to survey Barrett’s patients
Innovatienetwerk hyacint zoekt oplossingen voor bolbeschadiging
No full textBeschadigingen aan hyacenten die ontstaan tijdens de oogst en verwerking kunnen de teler veel geld kosten en uiteindelijk ook het imago van de hyacint negatief beïnvloeden. Een innovatienetwerkgroep van vijf telers werkte samen met diverse partijen om ne te gaan wat er aan beschadiging is te doe
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