186,411 research outputs found

    Immunogenicity and safety of a quadrivalent meningococcal tetanus toxoid-conjugate vaccine (MenACYW-TT): A review of the evidence and expert opinion

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    Introduction Serogroups A, B, C, W, X, and Y of Neisseria meningitidis are responsible for almost all cases of invasive meningococcal disease. In Italy, vaccination against serogroup B is recommended at 3–13 months, C at 13–15 months, and A, C, Y and W in adolescents (12–18 years). Four quadrivalent meningococcal conjugate vaccines are available. This review describes the available data on a quadrivalent meningococcal tetanus toxoid-conjugate vaccine (MenACYW-TT; MenQuadfi®; Sanofi). Areas covered We identified articles on quadrivalent meningococcal conjugate vaccines indexed on PubMed since 2000. Of the 524 studies identified, 10 human studies investigating the immunogenicity and safety of MenACYW-TT in toddlers, children aged 2–9 years, and individuals 10–55 or ≥56 years are described in detail. Expert opinion In Italy, pediatric and public health groups recommend amending the current vaccination schedule to include a booster dose between 6 and 9 years and quadrivalent vaccine in young adults (≥19 years), targeting waning protection after childhood vaccination and the age cohort with the highest carrier prevalence (adolescents and young adults). MenACYW-TT is a suitable meningococcal vaccine for current and pending recommendations based on high seroprotection rates and a low incidence of adverse events in these age groups. Moreover, it does not require reconstitution

    Joint Spatial and Tonal Mosaic Alignment for Motion Detection with PTZ Camera

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    Scene segmentation among background and foreground (moving) regions represents the first layer of many applications such as visual surveillance. Exploiting PTZ cameras permits to widen the field of view of a surveyed area and to achieve real object tracking through pan and tilt movements of the observer point of view. Having a mosaiced background allows a system to exploit the background subtraction technique even with moving cameras. Although spatial alignment issues have been thoroughly investigated, tonal registration has been often left out of consideration. This work presents a robust general purpose technique to perform spatial and tonal image registration to achieve a background mosaic without exploiting any prior information regarding the scene or the acquisition device. Accurate experiments accomplished on outdoor and indoor scenes assess the visual quality of the mosaic. Finally, the last experiment proves the effectiveness of using such a mosaic in our visual surveillance application

    A High Performance Exact Histogram Specification Algorithm

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    Real-time histogram specification methods aims to find a continuous function that transforms a source image to match a target distribution with the highest possible degree of accuracy. Many approaches privilege exact specification exploiting multi-valued ordering functions but incur in highly computational expensive implementations. Histogram specification algorithms can be classified according to computational complexity, image distortion and accuracy of reproduction of the target histogram. The method we propose permits an exact match of a given target histogram independently of the source image meanwhile introducing negligible image distortion. The simplicity of the method enables fast computation making the algorithm suitable for real time applications. Exhaustive experiments and accurate comparisons are carried out against the most representative approaches reported in literature. 1

    Vision-based markerless gaming interface

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    vision-based markerless human machine interface for gam- ing applications is presented. The use of a single consumer grade camera results in a practical, reliable and cheap interaction method. The use of natural features in place of visual markers permits to avoid instrumenting the scene with optical markers while preserving real-time computation and accuracy. Two full-fledged videogames, built on top of this interface, are proposed in order to assess the intuitiveness, speed and user-perceived fun-factor of the proposed approach

    People tracking using a Time-of-Flight depth sensor

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    Visually track several moving persons engaged in close interactions is known to be a very hard problem, though 3-D approaches based on stereo vision and plan-view maps offer much promise for dealing effectively with major issues such as occlusions and quick changes in body pose and appearance. However, in case of untextured scenes due to homogeneous objects or poor illumination, stereo-based tracking systems rapidly drop their performance. In this work, we present a real time people tracking system able to work even under severe low-lighting conditions. The system relies on a novel active sensor that provides brightness and depth images based on a Time of Flight (TOF) technology. The tracking algorithm is simple yet efficient, being based on geometrical constraints and invariants. Experiments accomplished under changing lighting conditions and involving multiple people closely interacting with each other have proved the reliability of the system

    sj-pdf-1-jig-10.1177_1069031X231154483 - Supplemental material for Brand Origin Effects During Economic Declines: Evidence from an Emerging Market

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    Supplemental material, sj-pdf-1-jig-10.1177_1069031X231154483 for Brand Origin Effects During Economic Declines: Evidence from an Emerging Market by Vitor Azzari, Felipe Zambaldi, Leandro Angotti Guissoni, Jonny Mateus Rodrigues and Eusebio Scornavacca in Journal of International Marketing</p
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