349 research outputs found

    From the 'Rescue of the Nation State' to the Emergence of European Spaces. EUIJ-Kansai Workshop on "New Research Horizons of the History of European Integration", May 10, 2008, Toyonaka (Osaka)

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    The aim of this paper is to make some contribution to the discussion on the future direction of the historical research on the European integration processes. What I intend to do here is, broadly, to link the contemporary European studies to the Historical studies, and concretely, to emphasise the transnational dimension of European integration. This exercise should be read as presenting my "wish list" to the Integration Historians

    Retroperitoneal liposarcoma surgically repaired with Boari flap

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    Retroperitoneal liposarcoma is rare. Here we describe a case of retroperitoneal liposarcoma in a 61-year-old male. Preoperative computed tomography revealed an intraabdominal huge mass, and a clinical diagnosis of liposarcoma. Intraoperatively, the mass involved the right kidney and bladder, completely surrounding the right ureter. The tumor and the lower half ureter were removed. Successful reconstruction of a neoureter was performed with the Boari flap coupled with nephropexy and a psoas hitch. The detailed salient steps performed in this case are reported, together with a review of the literature.61歳男。全身倦怠感を主訴とした。腹部に巨大な腫瘤を触れ、炎症所見、CRP値の上昇を認めた。CTにて巨大腫瘍を認め、MRIで第一腰椎の高さから骨盤部にかけて長径で30cmの腫瘍を認めた。手術を施行すると、腫瘍は周辺臓器と癒着し、右尿管を巻き込んで存在していた。右尿管を腫瘍とともに一塊として摘除したが、術中所見で後腹膜のあらゆる部位への直接浸潤を認め、腫瘍全摘除術は可能であったが根治性はないと判断した。そこで、術後化学療法施行の際の腎機能温存のため、右腎を温存することとした。Boari flapに腎を固定し、psoas hitchを併用した尿管-膀胱新吻合を行って尿路を再建した。病理組織学的に悪性線維性組織球症の所見を認め、liposarcoma、 dedifferentiated typeと診断した。術後2ヵ月で右側の水腎は認めず、順調に経過した

    SimpleBounce: A simple package for the false vacuum decay

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    We present SimpleBounce, a C++ package for finding the bounce solution for the false vacuum decay. This package is based on a flow equation which is proposed by the author R. Sato (2020) and solves Coleman–Glaser–Martin’s reduced problem (S. R. Coleman et al. 1978): the minimization problem of the kinetic energy while fixing the potential energy. The bounce configuration is obtained by a scale transformation of the solution of this problem. For models with 1–8 scalar field(s), the bounce action can be calculated with O(0.1) % accuracy in O(0.1) s. This package is available at http://github.com/rsato64/SimpleBounce

    Airgun-ocean bottom seismometer survey dataset

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    <p>These data are the seismic waveform recordsections and the P-wave velocity model obtained by Azuma et al. (JGR, 2018), collected through an airgun-ocean bottom seismometer (OBS) survey.</p> <p>The recordsections of 29 OBS are 'RAW data' with no waveform procedure and are formatted in SEG-Y. Length of each trace is 60 seconds. Offset ranges, distances along the survey line, position of each shot and OBS, are included in header.</p> <p>The final velocity data is written in netCDF.</p&gt

    APPLICATION OF A MARKOV PROCESS TO A MECHANICAL MODEL OF GRANULAR MATERIALS (2)

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    In the previous paper the author proposed a mechanical model of particulate materials as aMarkov process and explained the concepts of the potential barrier and the potential slip planewhich are introduced in the proposed model. Furthermore, the strain of particulate materialswas defined by using the change of contact angles at the contact points of particles and the dis-continuous motion of particles.In this paper the results of shearing tests obtained by the modified triaxial apparatus whichis designed and constructed, and can generate three different principal stresses are presented.The results of numerical experiments which are carried out by using the proposed model arealso presented. From both results it is shown that the proposed model can versatilely follow themechanical behaviours of particulate materials such as sands with complicated stress paths include-ing the stress reverse and repeated loading.In the previous paper the author proposed a mechanical model of particulate materials as aMarkov process and explained the concepts of the potential barrier and the potential slip planewhich are introduced in the proposed model. Furthermore, the strain of particulate materialswas defined by using the change of contact angles at the contact points of particles and the dis-continuous motion of particles.In this paper the results of shearing tests obtained by the modified triaxial apparatus whichis designed and constructed, and can generate three different principal stresses are presented.The results of numerical experiments which are carried out by using the proposed model arealso presented. From both results it is shown that the proposed model can versatilely follow themechanical behaviours of particulate materials such as sands with complicated stress paths include-ing the stress reverse and repeated loading

    Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing

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    SummarySpinal and bulbar muscular atrophy (SBMA), a progressive degenerative disorder, is caused by a CAG/glutamine expansion in the androgen receptor (polyQ AR). Recent studies demonstrate that skeletal muscle is an important site of toxicity that contributes to the SBMA phenotype. Here, we sought to identify critical pathways altered in muscle that underlie disease manifestations in AR113Q mice. This led to the unanticipated identification of gene expression changes affecting regulators of carbohydrate metabolism, similar to those triggered by denervation. AR113Q muscle exhibits diminished glycolysis, altered mitochondria, and an impaired response to exercise. Strikingly, the expression of genes regulating muscle energy metabolism is rescued following peripheral polyQ AR gene silencing by antisense oligonucleotides (ASO), a therapeutic strategy that alleviates disease. Our data establish the occurrence of a metabolic imbalance in SBMA muscle triggered by peripheral expression of the polyQ AR and indicate that alterations in energy utilization contribute to non-neuronal disease manifestations

    Multiplicative Characters and Gaussian Fluctuation Limits

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    It is known that extreme characters of several inductive limits of compact groups exhibit multiplicativity in a certain sense. In the paper, we formulate such multiplicativity for inductive limit quantum groups and provide explicit examples of multiplicative characters in the case of quantum unitary groups. Furthermore, we show a Gaussian fluctuation limit theorem using this concept of multiplicativity.The author gratefully acknowledges comments from Professor Makoto Katori at the early stage of this work. The author is grateful to Professor Yoshimichi Ueda for the useful discussion and his comments on the draft of this paper. Finally, the author gratefully thanks the referees for their kind reading and comments. This work was supported by JSPS Research Fellowship for Young Scientists PD (KAKENHI Grand Number 22J00573)

    Dataset: An empirical study on self-admitted technical debt in modern code review

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    This data was used in the IST paper "An Empirical Study on Self-Admitted Technical Debt in Modern Code Review". The program to use this data is published in GitHub (https://github.com/Yutaro-Kashiwa/ReviewSATD_RP) When you use this data in your research, please cite the following papers: ``` @article{Kashiwa:IST:2022:SATD_Review, author = {Yutaro Kashiwa and Ryoma Nishikawa and Yasutaka Kamei and Masanari Kondo and Emad Shihab and Ryosuke Sato and Naoyasu Ubayashi}, title = {An empirical study on self-admitted technical debt in modern code review}, journal = {Information and Software Technology}, volume = {146}, pages = {106855}, year = {2022}, url = {https://doi.org/10.1016/j.infsof.2022.106855}, doi = {10.1016/j.infsof.2022.106855} } ``

    Anharmonic vibrational computations with a quartic force field for curvilinear coordinates

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    The direct vibrational self-consistent field (VSCF) method, which combines anharmonic vibrational theory with electronic structure calculations, is a sophisticated theoretical approach to calculate the vibrational spectra of molecules from first principles. Combining the VSCF approach with the quartic force field (QFF) is a good alternative to direct VSCF, with a lower computational cost. QFF is a 4th-order Taylor expansion of the potential energy surface near an equilibrium geometry. In this study, a new strategy is proposed to derive the QFF in terms of normal coordinates; the QFF coefficients are determined through numerical differentiations of the energy by representing the normal coordinates in internal rather than Cartesian coordinates. The VSCF/QFF-internal method was implemented in the General Atomic and Molecular Electronic Structure System electronic structure program and applied to the evaluations of the fundamental vibrational frequencies of HNO2, HNO3, H2O dimer, and H2O trimer, using Møller-Plesset second order perturbation theory and the aug-cc-pVDZ and aug-cc-pVTZ basis sets. The results are much improved, especially for the intermolecular vibrational modes, compared with the Cartesian coordinate representation of the normal coordinates in the VSCF/QFF approach.This article is published as Harabuchi, Yu, Ryosuke Tani, Nuwan De Silva, Bosiljka Njegic, Mark S. Gordon, and Tetsuya Taketsugu. "Anharmonic vibrational computations with a quartic force field for curvilinear coordinates." The Journal of Chemical Physics 151, no. 6 (2019): 064104. DOI: 10.1063/1.5096167. Copyright 2019 Author(s). Posted with permission
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