1,354,888 research outputs found
FIGURE 2. Clematis iranica. A in A new species of Clematis L. (Ranunculaceae) from Iran
No full textFIGURE 2. Clematis iranica. A. Habit in field. B. Herbarium sample.Published as part of Habibi, Meisam, Nohooji, Majid Ghorbani, Baladehi, Mohammadhadi Heidari & Azizian, Dina, 2014, A new species of Clematis L. (Ranunculaceae) from Iran, pp. 99-106 in Phytotaxa 162 (2) on page 102, DOI: 10.11646/phytotaxa.162.2.4, http://zenodo.org/record/513200
FIGURE 3 in A new species of Clematis L. (Ranunculaceae) from Iran
No full textFIGURE 3. Pollen morphology under scanning electron microscopy (SEM). A–C. Clematis iranica. D–F. C. orientals.Published as part of Habibi, Meisam, Nohooji, Majid Ghorbani, Baladehi, Mohammadhadi Heidari & Azizian, Dina, 2014, A new species of Clematis L. (Ranunculaceae) from Iran, pp. 99-106 in Phytotaxa 162 (2) on page 104, DOI: 10.11646/phytotaxa.162.2.4, http://zenodo.org/record/513200
Treatment options of metastatic and nonmetastatic VIPoma: a review
No full textPURPOSE: VIPoma belongs to the group of neuroendocrine neoplasms. These tumours are located mostly in the pancreas and produce high levels of vasoactive intestinal peptide (VIP). In most cases, a metastatic state has already been reached at the initial diagnosis, with high levels of VIP leading to a wide spectrum of presenting symptoms. These symptoms include intense diarrhoea and subsequent hypopotassaemia but also cardiac complications, with life-threatening consequences. Treatment options include symptomatic therapy, systemic chemotherapy and targeted therapy, as well as radiation and surgery. Due to the low incidence of VIPoma, there are no prospective studies or evidence-based therapeutic standards to date. METHODS: To evaluate the possible impact of different therapy strategies, we performed literature research using PubMed. RESULTS: All possible treatment modalities for VIPoma have at least one of two therapy goals: antisecretory effects (symptom control) and antitumoural effects (tumour burden reduction). Symptomatic therapy is the most important in the emergency setting to rehydrate, balance electrolytes and stabilise the patient. Symptomatic therapy is also of great importance perioperatively. Somatostatin analogues play a major role in symptom control, although their efficiency is often limited. Chemotherapy may be effective in reaching stable disease for a certain time period, although its impact on symptom control is limited and often delayed. Among targeted therapy options, the usage of sunitinib appears to be the most effective in terms of symptom control and showing antitumoural effects at the same time. Experience with radiation is still limited; however, local ablative procedures seem to be promising options. Peptide receptor radiotherapy (PRRT) with radiolabelled somatostatin analogues (SSAs, 177Lu-DOTATATE) offers a targeted approach, especially in patients with high somatostatin receptor density. Surgery is the first-line therapy for nonmetastatic VIPoma. Additionally, if the resection of all visible tumour lesions is possible, the surgical approach seems preferable to other strategies in highly symptomatic patients. The role of surgery in very advanced stages where only tumour debulking is possible remains debatable. However, a high rate of immediate symptom control can be achieved by tumour debulking followed by somatostatin therapy, although the impact on survival remains unclear. CONCLUSION: Surgery is the only curative option for nonmetastatic VIPoma. Additionally, surgery should be a first-line therapy option for highly symptomatic patients, especially if the resection of all tumour lesions (primary tumour and metastasis) is achievable. In frail patients, other modalities can be used
FIGURE 4 in A new species of Clematis L. (Ranunculaceae) from Iran
No full textFIGURE 4. Shape and anticlinal wall model of the epidermal cells on adaxial and abaxial surfaces. A–B. Clematis iranica. C–D. C. orientalis. Scale bar 100µm.Published as part of Habibi, Meisam, Nohooji, Majid Ghorbani, Baladehi, Mohammadhadi Heidari & Azizian, Dina, 2014, A new species of Clematis L. (Ranunculaceae) from Iran, pp. 99-106 in Phytotaxa 162 (2) on page 105, DOI: 10.11646/phytotaxa.162.2.4, http://zenodo.org/record/513200
FIGURE 5. Ideograms and somatic metaphase cells. A. Clematis iranica. B. C. orientalis. C. C. iranica D. C. orientalis. Scale bar 10 in A new species of Clematis L. (Ranunculaceae) from Iran
No full textFIGURE 5. Ideograms and somatic metaphase cells. A. Clematis iranica. B. C. orientalis. C. C. iranica D. C. orientalis. Scale bar 10 µm.Published as part of Habibi, Meisam, Nohooji, Majid Ghorbani, Baladehi, Mohammadhadi Heidari & Azizian, Dina, 2014, A new species of Clematis L. (Ranunculaceae) from Iran, pp. 99-106 in Phytotaxa 162 (2) on page 105, DOI: 10.11646/phytotaxa.162.2.4, http://zenodo.org/record/513200
FIGURE 1 in A new species of Clematis L. (Ranunculaceae) from Iran
No full textFIGURE 1. Clematis iranica: A. Habit. B. Flower (× 3). C. Sepal (× 10). D. Anther (× 1). E. Fruiting Head (× 3). F–G. Achene (× 2).Published as part of Habibi, Meisam, Nohooji, Majid Ghorbani, Baladehi, Mohammadhadi Heidari & Azizian, Dina, 2014, A new species of Clematis L. (Ranunculaceae) from Iran, pp. 99-106 in Phytotaxa 162 (2) on page 101, DOI: 10.11646/phytotaxa.162.2.4, http://zenodo.org/record/513200
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
sj-jpg-1-tag-10.1177_17562848211051132 – Supplemental material for Surgical treatment of metastatic VIPoma: a case report
No full textSupplemental material, sj-jpg-1-tag-10.1177_17562848211051132 for Surgical treatment of metastatic VIPoma: a case report by Azadeh Azizian, Alexander König, Amelie Hartmann, Frank Schuppert, Ali Seif Amir Hosseini, Julia Kitz and Michael Ghadimi in Therapeutic Advances in Gastroenterology</p
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