193 research outputs found
PROTOTYPE DEVELOPMENT AND EXPERIMENTAL VERIFICATION OF A CAST MODULAR CONNECTOR FOR SEISMIC-RESISTANT STEEL FRAMES.
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Experiments with non-uniform sediment in case of bed-load transport
An experimental study was carried out in the framework of a research project concerning the development of a mathematical model for morphological computations in rivers in case of non-uniform sediment. The study consists of a series of laboratory experiments in a straight flume under steady, uniform (equilibrium) conditions with a restriction to bed-load transport and dune regime. The flume was fed upstream by different mixtures of two very narrow sieved size fractions. During one experiment the total amount and composition of the input mixture, the water discharge and the downstream water level were kept constant. When equilibrium was reached besides regular registrations of water and bed level the dunes were extensively sampled. The latter occurred in such a way that vertical probability distributions of the size fractions could be determined. The main results of the experiments are: (i) Vertical sorting of the size fractions occurred in all experiments: at the steep lee side of the dunes the coarse size fraction is generally deposited at a lower level than the fine size fraction. Differences in volume concentration per size fraction until 30% occur between upper and lower layers. (ii) A transition layer was found which is generally below the propagating dunes; it has a relatively coarse composition (vertical sorting:) and has a thickness of 0.1 - 0.5 H (H = average dune height). Exchange of size fractions between this layer and the upper bed layer occurs at a time scale much larger than the dune period. (iii) Because of the phenomena described above several assumptions in a mathematical model for non-uniform sediment (Ribberink, 1980) concerning the transport layer and the deposition/erosion of size fractions to/from non-moving bed are generally not fulfilled. (iv) Data are obtained for the verification and development of semi empirical components in the mathematical model (i.e. transportformula per size fraction, predictors for dune height and bed roughness).The theory of Egiazaroff (1965) concerning the critical bed shear stress per size fraction seems to be useful in a bed-load formula per size fraction of the type of Meyer-Peter & Mueller (1948). (v) A bed sampling technique was developed and suggestions are made concerning the conditions of a non -equilibrium experiment which has the aim to verify the above-mentioned mathematical model for non-uniform sediment.Hydraulic EngineeringCivil Engineering and Geoscience
Sleeve Gastrectomy Pathologies: A Single-Center Retrospective Analysis
Sleeve Gastrectomy (SG) has emerged as a prominent surgical approach in the battle against obesity, gaining widespread recognition for its effectiveness in promoting significant weight loss and improving metabolic health. However, despite its increasing popularity, the impact of SG on the histological and pathological characteristics of the gastrointestinal tract remains a subject of intensive research. This retrospective study, conducted at Istinye University, aimed to investigate the pathological outcomes of 530 SG procedures performed between June 1, 2022, and 2023. The study included demographic information, comorbidities, operative details, and both endoscopic and pathological findings. Our analysis uncovered notable trends in post-SG endoscopic and pathological findings. Gastritis was observed in a significant portion of patients, where 65.4% exhibited endoscopic gastritis and 70.8% showed pathologi cal gastritis. H. pylori infection, a known factor in gastritis development, was detected in 27.9% endoscopically and 35.6% pathologically. Further investigation is warranted to explore the disparities between endoscopic and pathological detection rates an d assess diagnostic accuracy. The presence of comorbidities showed a significant association with gastritis (p < 0.05), underscoring the potential interplay between systemic health conditions and gastric pathologies following SG. No significant relationshi p was found between gender and pathological findings. This study offers valuable insights into the pathological outcomes of SG and emphasizes the importance of postoperative monitoring and the management of gastric health. Routine endoscopy remains a funda mental component of postoperative care for bariatric surgery patients, contributing significantly to their long-term well-being and optimizing surgical outcomes. © 2023, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved
Jejunal diverticulum perforation resulting from distal mechanic obstruction: a case report
Excluding Meckel's diverticulum, jejunum and ileum diverticula are acquired diverticula which are rarely observed and have an asymptomatic course. They are mostly observed in elderly patients. Men are twice as likely as women to have diverticula. The complications like inflammation, bleeding, obstruction and perforation may develop in less than 10% of patients with jejunal diverticula. Perforation, as an uncommon complication, may occur following diverticulitis in 82%, blunt trauma in 12%, and impact of foreign body in 6% of cases. Herein we present a 62 year old man operated emergently due to development of acute abdomen that resulted from perforation caused by an increased jejunal and diverticular pressure secondary to rectal obstruction without any common factors mentioned for diverticular perforation. We performed resection and anastomosis at operation
Technical details of laparoscopic sleeve gastrectomy
Obesity is an expanding threat globally. Several surgical procedures have been developed to achieve the best outcomes in obesity. One of them is laparoscopic sleeve gastrectomy that was first applied in 1999 to initiate weight loss in overweight patients. Laparoscopic sleeve gastrectomy is a restrictive bariatric technique consisting of subtotal partial vertical gastrectomy with the preservation of the pylorus, and a gastric tube is created as a continuation of the esophagus along the lesser curvature with the resection of the fundus, corpus, and antrum. Although this technique is routinely-applied all over the world, the technical details are still controversial. This review aims to define the tips and tricks for the sleeve gastrectomy technique and discuss the controversial subjects in this technique
pH Transistor Nanoprobe Advances Cancer Detection and Surgery
The file named "ZHAO-DISSERTATION-2015.pdf" is the primary dissertation file. Four (4) supplemental files are also available and may be viewed individually.The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.Cancer exhibits profound genetic and phenotypic differences, therefore broad yet cancer-specific detection of malignant tumors is challenging. Anatomy-based imaging modalities (e.g., CT, MRI) have good spatial resolution but provide little disease-specific information. 2-Deoxy-2-[18F]fluoroglucose positron emission tomography (FDG-PET) allows near universal tumor detection by leveraging altered tumor metabolism, but it is limited by low spatial resolution and high false positive rates.
Here we report a near infrared fluorescent pH transistor nanoprobe targeting extracellular tumor acidosis from dysregulated pH that drives many invasive properties of cancer. The nanoprobes delineated tumors with high spatial resolution (<1 mm) for a broad range of in vivo tumor models using different clinical cameras. Our results show targeting tumor pH downstream from deregulated metabolism provides a broad strategy with improved cancer specificity which makes the nanoprobe a useful adjuvant method to reduce false rates after FDG-PET.
To validate the ability of nanoprobes to provide real-time, highly sensitive and specific illumination of cancer, we performed tumor acidosis guided detection of occult disease as well as surgery and demonstrated significantly improved long-term survival benefit in head/neck and breast cancers.
This binary nanotransistor design achieves digitization of an analog biologic signal (pH) for signal amplification and noise reduction that improves the accuracy of cancer detection, intraoperative tumor visualization, and imaging of therapeutic response while providing a powerful tool for understanding dysregulated pH and cellular energetics in cancer
Vyhodnocení dopadu doporučení ČNB na spotřebitele využívajícího účelového úvěru na bydlení
Goal of this thesis is to gain perspective on the change of situation of con-sumer that uses loans purposed for securing own housing based on recom-mendations by Czech National Bank for providers of these loans. In order to achieve this goal, author will use method of description to sum-up the theo-ry and current situation on the loan market. In the next part, author will try to simulate the situation of the household of two consumers with income on the level of median wage, which wants to use the housing-purposed loan, and how its ability to take certain amount of money and its purchasing power have changed in the last five years. Author will interpret findings of his empirical analysis and suggest possible solution which could improve current state of the matter
Unemployed in network of the professional support: subjective participant or passive con-sumer?
In this article the author tried to answer the question, what kind of role has the unemployed, who are using network of the professional support. For this purpose the author discussed the way of support for people staying unemployed and the relations between them and the helper. This subject was chosen, because of progressing professionalism in help services, which could lead to loss help in overcome difficult life situation. The support was showed just as unemployed see it. To emphasize, how few changes was made in time the author compared nowadays help relations and the situation of unemployed from the stories of the past, which are present in the book “Pamiętniki bezrobotnych”
Samuel Noah Kramer: 10-06-1981
Samuel Noah Kramer was a Sumerian history and language expert and the author of over 25 books and 150 articles on Sumer. He begins the interview by reading a piece of Sumerian literature and continues by discussing what Sumerian literature is about, the time period it was written in, and the types of literature that the Sumerians wrote. He discusses how he got into cuneiform, the system of writing developed by the Sumerians, and talks about coming to the United States as a child. Kramer concludes the interview by discussing how he became an archaeologist.https://digitalcommons.brockport.edu/writers_videos/1020/thumbnail.jp
Samuel Noah Kramer: 10-06-1981
Samuel Noah Kramer was a Sumerian history and language expert and the author of over 25 books and 150 articles on Sumer. He begins the interview by reading a piece of Sumerian literature and continues by discussing what Sumerian literature is about, the time period it was written in, and the types of literature that the Sumerians wrote. He discusses how he got into cuneiform, the system of writing developed by the Sumerians, and talks about coming to the United States as a child. Kramer concludes the interview by discussing how he became an archaeologist.Archived web contentSUNY BrockportWriters Forum Video
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