26,796 research outputs found
Treatment of breast cancer during pregnancy: regimen selection, pregnancy monitoring and more...
No full textHa-Dibbur Ha-Ivri
No full textHebrew Speech, a manual for beginners for the study of Hebrew according to the Natural Method). Author: M. Krinsky. Illustrator: H. Goldberg. Publisher: Ha-Or Publishing. . 146 pp. 254 b/w ills. (+1 color chart) + cover b/w ill. primer.Digital imagedigitize
Exploring the safety of chemotherapy for treating breast cancer during pregnancy
No full textIntroduction: The diagnosis of breast cancer during pregnancy (BCP) represents a unique challenge to the patient, her family and the treating physician. The proper management of this critical clinical situation is crucial, and requires a multidisciplinary approach. A proper understanding of the safety of chemotherapy during pregnancy is a vital step to avoid detrimental consequences on the mother and the fetus.Areas covered: The aim of this article is to review the available evidence on the safety of chemotherapy administration in managing BCP.Expert opinion: The rule of thumb of chemotherapy - avoiding first trimester exposure and starting therapy in the second trimester - can be considered applicable for classic agents that are used in managing pregnant breast cancer patients. Anthracycline-based regimens are considered the standard of care in managing BCP. Recently, a growing amount of data suggests the safety of taxanes during pregnancy. Pregnancy in cancer patients should be considered as "high risk": once the systemic treatment is initiated, regular fetal monitoring is highly recommended. Emerging data are available on the relative long-term safety secondary to anthracycline exposure during pregnancy. A continued monitoring of the health of individuals with prenatal exposure to chemotherapy into adulthood is recommended for the possible occurrence of long-term side effects.SCOPUS: re.jinfo:eu-repo/semantics/publishe
Author Ha Jin at Kalamazoo College
No full textPhotographer unknown.Author Ha Jin's book "Waiting" was selected for the 2002 Summer Common Reading program at Kalamazoo College. The author visited campus that year as part of the program
Developing A Marketing Recruitment Strategy For International Business
No full textOver the last 20 years, recruiting strategies have changed considerably due to the expansion of technology and the Internet. Human resources are also contemplated as the core competitive factor of businesses. This research is conducted to systematize the theoretical basis related to recruitment marketing. Moreover, at various phases, it employs both qualitative and quantitative research approaches.
In terms of the empirical component, the owner of the corporate case provided qualitative data. In contrast, quantitative data from possible candidates were reviewed. The theoretical portion gives the audiences a fundamental understanding of recruiting and the use of a recruitment marketing strategy. The author researched some surveys and case studies to gather data from both employees and employers.
On the whole, the research findings disclosed the importance of recruitment marketing to international enterprises. Businesses should focus on recruitment marketing to improve recruitment efficiency and reach a bigger pool of potential talents. In the end, the author designated some recommendations for businesses to improve recruitment marketing effectiveness
Reproductive behaviors and risk of developing breast cancer according to tumor subtype: A systematic review and meta-analysis of epidemiological studies
No full textBackground Breast cancer is composed of distinct subtypes defined mainly based on the expression of hormone receptors (HR) and HER2. For years, reproductive factors were shown to impact breast cancer risk but it is unclear whether this differs according to tumor subtype. In this meta-analysis we evaluated the association between parity, age at first birth, breastfeeding and the risk of developing breast cancer according to tumor subtype. Methods PubMed and Embase were searched to identify epidemiological studies that evaluated the impact of parity and/or age at first birth and/or breastfeeding on breast cancer risk with available information on HR and HER2. Tumor subtypes were defined as: luminal (HR-positive, HER2-negative or HER2-positive), HER2 (HR-negative, HER2-positive) and triple-negative (HR-negative, HER2-negative). Summary risk estimates (pooled OR [pOR]) and 95% confidence intervals (CI) were calculated using random effects models. The MOOSE guidelines were applied. Results This meta-analysis evaluated 15 studies, including 21,941 breast cancer patients and 864,177 controls. Parity was associated with a 25% reduced risk of developing luminal subtype (pOR 0.75; 95% CI, 0.70–0.81; p < 0.0001). Advanced age at first birth was associated with an increased risk of developing luminal subtype (pOR 1.15; 95% CI, 1.00–1.32; p = 0.05). Ever breastfeeding was associated with a reduced risk of developing both luminal (pOR 0.77; 95% CI, 0.66–0.88; p = 0.003) and triple-negative (pOR 0.79, 95% CI, 0.66–0.94; p = 0.01) subtypes. Conclusions The reproductive behaviors impact the risk of developing breast cancer but this varies according to subtype.SCOPUS: re.jinfo:eu-repo/semantics/publishe
All of Life as Worship, with Theological Librarian, PhD Candidate, and Author Sam Ha
No full textSam Ha, PhD Candidate and Meeter Center for Calvin Studies Curator, recently released his book, A Day of Worship: Adoring God in Every Moment. The book is a pastorally-rich, theologically in-depth exploration of how each moment of life-mundane and special-can be a form of worship before God. Within its first week, it became the 2nd most sold book in Christianity & theology books in Sam’s home country of Korea
Semiometrics: producing a compositional view of influence
No full textHigh-impact academic papers are not necessarily the most cited. For example, Einstein's 'Special Relativity' paper from 1905 received (and continues to receive) fewer citations from other papers than his 'Brownian Motion" paper of the same year, despite the former radically changing the course of an entire scientific discipline to a much greater extent. Similarly, 'impact' metrics using citation count alone are, it is argued, not adequate for determining the scientific influence of papers, authors or small groups of authors. Although valid, they remain controversial when used to determine influence of larger groups or journals. While the term 'impact' has become closely linked to a journal's citation-based Journal Impact Factor score, this thesis uses the term 'influence' to describe the wider effectiveness of research, combining citation and metadata analysis to allow richer calculations to be performed over large-scale document networks. As a result, more qualitative influence ratings can be determined and a broader outlook on scientific disciplines can be produced. These ratings are best applied using an ontology-based data source, allowing more efficient inference than under a traditional RDBMS system, and allowing easier integration between heterogeneous data sources. These metrics, termed 'Semantic Bibliometrics' or 'Semiometrics', can be applied at a variety of levels of granularity, allowing a compositional framework for impact and influence analysis. This thesis describes the process of data preparation, systems architecture, metric value and data integration for such a system, introducing novel approaches at all four stages, thereby creating a working semiometrics system for determining influence at different semantic levels of granularity
Detection of large sequence insertions by a hybrid approach that combine de novo assembly and resequencing of medium-coverage genome sequences
No full textLarge sequence insertion (LSI) is one of the structural variations (SVs) that may cause phenotypic differences in plants. To identify the LSIs using medium-coverage sequencing data of four wild soybean (Glycine soja) genotypes, we designed a hybrid approach combining de novo assembly and read mapping. Total reads and reads with both ends unmapped were independently assembled into “ordinary contigs” and “orphan contigs”, respectively, and subjected to pairwise alignment and stringent filtering. This approach predicted 24 LSIs averaging 2,682 bp in size, with no overlap with SVs detected by Pindel, BreakDancer, or ScanIndel, and they were validated by PCR. Compared with the soybean (Glycine max) reference genome, 20 LSIs were located outside genic regions. One of the four LSIs within a genic region, LSI05, is located in the coding DNA sequence region of a protein kinase superfamily gene (Glyma.08G123500). It caused delayed translation initiation and loss of 24 amino acids in the wild soybean genotype CW12. LSI05 was more frequently observed in 29 G. soja accessions than in 34 G. max accessions. Identified LSIs would be genomic resources harboring novel gene contents for studying SVs and improving crops. Moreover, our cost-efficient approach may be applicable to other plant species.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
Recommendations for author signatures on scientific output at the Universitat Oberta de de Catalunya
No full textAquest document ha estat actualitzat per "Author signature recommendations for scientific output at the Universitat Oberta de Catalunya", aprovat el 20 de març de 2018. Disponible a: http://hdl.handle.net/10609/76965Este documento ha sido actualitzado por "Author signature recommendations for scientific output at the Universitat Oberta de Catalunya", aprovado el 20 de marzo de 2018. Disponible a: http://hdl.handle.net/10609/76965El 9 d'octubre de 2014 la Comissió de Recerca i Doctorat de la Universitat va aprovar les Recomanacions per a la signatura dels autors en la producció científica de la Universitat Oberta de Catalunya. Aquest document és un recull de recomanacions per al personal de la UOC pel que fa a la seva signatura en qualsevol publicació científica en què participi. Aquestes recomanacions volen el següent: fomentar l'ús d'una signatura única; fomentar l'ús correcte de la filiació institucional dels autors de la UOC; millorar i assegurar una correcta visibilitat dels autors en les bases de dades de publicacions, repositoris, cercadors a la xarxa, etc.; facilitar el seguiment de la producció científica de la UOC; fomentar l'ús d'una signatura de correu electrònic consistent i que doti de solidesa la marca UOC.El 9 de octubre de 2014 la Comisión de Investigación y Doctorado de la Universidad aprobó las Recomendaciones para la firma de los autores en la producción científica
de la Universitat Oberta de Catalunya. Este documento es una compilación de recomendaciones para el personal de la UOC en lo referente a su firma en cualquier publicación científica en la que participe. Estas recomendaciones buscan: fomentar el uso de una firma única; fomentar el uso correcto de la filiación institucional de los autores de la UOC; mejorar y asegurar una correcta visibilidad de los autores en las bases de datos de publicaciones,
repositorios, buscadores en la red, etc.; facilitar el seguimiento de la producción científica de la UOC; fomentar el uso de una firma de correo electrónico consistente y que dote de solidez a la marca UOC.On 9 October 2014, the Research and Doctorate Scientific Committee approved the Recommendations for author signatures on scientific output at the Universitat Oberta de de Catalunya. This document presents a series of recommendations for UOC staff on signing scientific publications to which they have contributed. These recommendations are intended to: encourage authors to use a unique signature; promote the correct identification of UOC authors' affiliations;
ensure satisfactory visibility of UOC authors in publication databases, repositories, web searches, etc.; facilitate the monitoring of the UOC's scientific output; promote the use of a standardised email signature that strengthens the UOC's brand image
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