1,720,955 research outputs found
Exploring the relationship between in vivo sodium concentration and cortical excitability in human partial epilepsy
No full textLes patients souffrant d'épilepsie résistante aux médicaments sont éligibles pour une résection les régions responsables de la génération des crises (c'est-à-dire la zone épileptogène (ZE)). Le patient épileptique virtuel (VEP) est un modèle de cerveau virtuel personnalisé, basé sur des données anatomiques et fonctionnelles spécifiques au patient, qui peut être utilisé pour estimer la ZE. L'objectif du projet était d'évaluer si les priors, basés sur l'IRM quantitative du sodium (23Na-IRM) peuvent fournir des résultats complémentaires ou même meilleurs. Nous avons d'abord approfondi l'investigation, en utilisant une procédure où les régions d'intérêt sont définies autour du contact des électrodes SEEG, en extrayant les données de l'IRM 23Na à 7T et de l'imagerie spectroscopique par MR protonique 3D (1H-MRSI) à 3T, définissant une approche d'imagerie multimodale. Nos résultats montrant une augmentation des concentrations de sodium et une diminution des concentrations de NAA dans l'EZ par rapport aux contrôles et aux autres zones des patients, sont en accord avec l'hypothèse d'une défaillance énergétique dans les régions épileptiques associée à une réorganisation tissulaire étendue. Dans la deuxième partie du projet, nous avons d'abord proposé une approche d'apprentissage automatique à partir des données d'IRM 23Na pour prédire l'EZ. Les prédictions résultantes sont utilisées comme priors dans la VEP. Nous avons découvert que l'estimation de l'EZ basée sur les priors de l'IRM 23Na peut compléter le diagnostic initial du VEP. À l'avenir, les priors pourraient être dérivés d'approches d'imagerie multimodale, en recherchant plus de précision et moins d'invasivité.Patients suffering from drug-resistant epilepsy are eligible for surgery aiming to remove the regions responsible for seizure generation (i.e. the epileptogenic zone (EZ). The surgical outcome is linked to the precision of the EZ definition during the presurgical evaluation. The Virtual Epileptic Patient (VEP) is a data-driven, personalized virtual brain model derived from patient-specific anatomical and functional data that can be used to help to estimate the EZ. The aim of the project was to evaluate if priors, based on quantitative sodium MRI (23Na-MRI) can provide complementary or even better results. Before converting 23Na-MRI data to priors for the VEP, we first deepen the investigation, using a procedure where regions of interest are defined around SEEG electrodes contact, extracting 23Na-MRI at 7T and 3D proton MR spectroscopic imaging (1H-MRSI) at 3T data, defining a multimodal imaging approach framework. Our results, showing increased sodium and decreased NAA concentrations in the EZ compared to controls and other zones in patients, are in agreement with the energetic failure hypothesis in epileptic regions associated with widespread tissue reorganization. In the second part of the project, we first proposed the mapping from 23Na-MRI features to predict the EZ via a machine learning approach. The resulting predictions are used as priors in the VEP. We found out that 23Na-MRI prior based VEP estimation of the EZ is at least as good as SEEG based priors, and can also complement their diagnostics. In the future, priors may be derived from multimodal imaging approaches, seeking for more precision and less invasiveness
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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