33 research outputs found
Cardiac Magnetic Resonance Evaluation of the Impact of Interventricular and Intraventricular Dyssynchrony on Cardiac Ventricular Systolic and Diastolic Function in Patients With Isolated Left Bundle Branch Block
No full textVentricular dyssynchrony significantly impairs cardiac performance. However, the independent role of interventricular dyssynchrony (interVD) and intraventricular dyssynchrony (intraVD) in the development of abnormalities of systolic and diastolic performance is unclear. Cardiac magnetic resonance imaging was performed in 39 patients with left bundle branch block and 13 healthy patients. Structural and functional parameters of the left ventricle and degrees of interVD and intraVD were measured. We found that interVD was inversely correlated with left ventricular (LV) ejection fraction (r = -0.8, p <0.0001) and positively correlated with LV end-diastolic volume (r = 0.4, p <0.01), LV end-systolic volume (r = 0.6, p <0.0001), and LV mass (r = 0.4, p <0.01), thus indicating that interVD significantly affects systolic function and favors ventricular remodeling. Multivariate analysis further confirmed that interVD was an independent predictor of systolic dysfunction. Interestingly, we found that interVD was not associated with abnormalities of diastolic performance. Conversely, we found that intraVD significantly impaired diastolic function, whereas it had no effect on systolic function. IntraVD was inversely correlated with peak filling rate (r = -0.7, p <0.0001) and 1/2 filling fraction (r = 0.4, p = 0.04) and positively correlated with time to peak filling rate (r = 0.6, p <0.0001), validated parameters of diastolic function. Multivariate analysis confirmed that intraVD was an independent predictor of diastolic dysfunction. In conclusion, our study suggests that the 2 components of ventricular dyssynchrony differently affect cardiac performance. If confirmed in prospective studies, our results may help to predict the prognosis of patients with left bundle branch block and different degrees of interVD and intraVD, particularly those subjects undergoing cardiac resynchronization therapy. (c) 2012 Elsevier Inc. All rights reserved. (Am J Cardiol 2012;110:1651-1656
Neuroleptic malignant syndrome with metoclopramide overdose coexisting with Clostridium difficile diarrhea
No full textA Severe Case Of Lenalidomide Induced Interstitial Pneumonitis Requiring Intensive Critical Care And Mechanical Ventilation
No full textCOMPARISON OF RADIATION EXPOSURE BETWEEN INTERVENTIONAL AND NONINVASIVE CARDIOLOGIST DURING STRUCTURAL CARDIAC INTERVENTIONS
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A new semi-automated algorithm for determining LV volumes is especially valuable for inexperienced users
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Achenbach Syndrome: A Case Report
Get PDFIntroduction: Achenbach syndrome is a rare, benign condition characterized by painful discoloration ofa finger. Recognition of this syndrome prevents unnecessary costly workup and risky interventions.
Case Report: A healthy, 54-year-old female was transferred to our emergency department (ED) from acommunity ED for vascular evaluation of discoloration and numbness to her finger. After extensiveworkup, medical intervention, and consultation with multiple specialists, she was diagnosed withAchenbach syndrome.
Conclusion: Emergency physicians may practice good healthcare stewardship and limit invasive,potentially harmful, and expensive workup by reassuring patients of the benign nature of this condition
LONG-TERM OUTCOMES OF MODERATE TO SEVERE MITRAL REGURGITATION SEEN IN PATIENTS REFERRED FOR STRESS ECHOCARDIOGRAPHY
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A new semi-automated algorithm for determining LV volumes is especially valuable for inexperienced users
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