303 research outputs found
Welcome
No full textAllison Boye - Welcome
Director - Center for Teaching and Learning Collin College
Marc Azard - Introduction of Keynote Speaker
Professor of English -Collin College
Dr. Lizbett Tinoco - Keynote Address
Professor - Texas A&M - San Antoni
Lunch/Networking
No full textLunch is included with registration. Let’s continue the spirited conversations of composition and collegiality with the Trends presenters and our esteemed keynote speaker, Dr. Tinoco
A Conversation with Marc Gallicchio
No full textThe 2018-2019 Davis Fellow Michael Fischer sat down with Professor of History Marc Gallicchio of Villanova University. Dr. Gallicchio, who earned his PhD at Temple University, is co-author of the 2017 book Implacable Foes: War in the Pacific, 1944-1945, along with his mentor, Waldo Heinrichs
ERRATUM: Repetitive recombinant human bone morphogenetic protein 2 injections improve the callus microarchitecture and mechanical stiffness in a sheep model of distraction osteogenesis
No full textDue to a technical error, Dr. Marc-Frederic Pastor was omitted from the author list of this article. The correct author details appear above.<br /
The Fierce Urgency of Now, Keynote Address by Marc Lamont Hill
No full textTHE FIERCE URGENCY OF NOW
A CELEBRATION OF THE LIFE AND LEGACY OF
DR. MARTIN LUTHER KING JR.
THURSDAY, JAN. 15, 2015, 7 PM.
LOEB PLAYHOUSE, STEWART CENTER
Dr. Martin Luther King Jr. Keynote Address by
MARC LAMONT HILL
Marc Lamont Hill is an award-winning journalist, author, activist and television personality who has appeared on CNN, BET, and HuffPost Live. He is also Distinguished Professor of African American Studies at Morehouse College.
His talk will be preceded by a 6 p.m. candlelight vigil march from the Black Cultural Center to Loeb Playhouse, hosted by Alpha Phi Alpha Fraternity.
For a complete listing of events and more on Dr. King, go to purdue.edu/mlk
Like Purdue MLK events on Facebook at PurdueBCC
PURDUE UNIVERSITY division of diversity and inclusion
Sponsored by the Division of Diversity and Inclusion
EA/EOU • Produced by Purdue Marketing and Media ODI.14.5123
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Recommended from our members
Review Essay: 'Elementary My Dear Hameed': Postcolonial Crime Fiction; Nels Pearson and Marc Singer, ed <i>Detective Fiction in a Postcolonial and Transnational World</i>; Ibne Safi <i>The Laughing Corpse</i>; Ibne Safi <i>Dr Dread</i>; M C Dutton <i>The Singhing Detective</i>
No full textThis review essay covers criticism and fiction, all relating to postcolonial crime genres. It evaluates 'Detective Fiction in the Postcolonial and Transnational World' by Nels Pearson and Marc Singer, and reviews the republished work of the Urdu crime author Ibne Safi ('The Laughing Corpse' and 'Dr Dread'). It also covers a more recent crime fiction by M.C. Dutton - 'The Singhing Detective'
About Quaternary prevention in Public health ; comment on Dr Jong-Myon Bae paper
No full textpeer reviewedThe recent paper of Dr Jong-Myon Bae about Quaternary Prevention and Public Health in your journal has attracted my interest. The spread of this concept is beyond all expectation and I am quite happy it contributes to the analytic thinking of complexity of health care.
The particular application of the quaternary prevention (P4) concept is absolutely brilliant. Nevertheless I would propose some slight modifications to the table 1 edited by the author which I have taken the liberty to reproduce here with the due authorization of Dr Bae and after several mail exchanges with him
Intuitive analog circuit design
No full textIntuitive Analog Circuit Design outlines ways of thinking about analog circuits and systems that let you develop a feel for what a good, working analog circuit design should be. This book reflects author Marc Thompson's 30 years of experience designing analog and power electronics circuits and teaching graduate-level analog circuit design, and is the ideal reference for anyone who needs a straightforward introduction to the subject. In this book, Dr. Thompson describes intuitive and ""back-of-the-envelope"" techniques for designing and analyzing analog circuits, including transistor amplif
The discovery of SycO reveals a new function for type three secretion effector chaperones
No full textThe Type Three Secretion (T3S) system is a device used by many Gram-negative pathogens that allows bacteria to deliver effector proteins straight into the eukaryotic cell cytosol. These effectors interfere with various signaling pathways to subvert the host cell functions. The secretion machinery of the T3S system consist of a basal body spanning the bacterial inner and outer membrane followed by a stiff hollow needle outside the bacterium. The fully assembled secretion apparatus constitute a continuous hollow conduit that connects the bacteria to the eukaryotic target cell. After cell contact, virulence proteins -called effectors- are injected directly into the cytosol of the host cell via the T3S apparatus. Several effectors of the T3S system require the assistance of specific cytosolic chaperones to be efficiently exported. There are three classes of T3S chaperones. Effector proteins are assisted by Class I chaperones. Although Class I chaperones are well characterized, their main function is still a matter of controversy. In this thesis, we demonstrate that orf155 encodes a specific chaperone for the effector YopO that we called SycO. We showed that SycO enhances YopO secretion in vitro and is required for translocation of YopO into infected cells. By pulldown assay we demonstrated that residues 20 to 77 of YopO are required and sufficient for SycO binding. Using crosslinking experiments and size exclusion chromatography analysis, we determined the stoichiometry of purified SycO and YopO-SycO complexes. SycO alone forms dimers in solution and the YopO-SycO complex has a 1:2 stoichiometry. These results suggested that SycO is a typical chaperone of the Class I. YopO is a serine/theronine kinase that interacts with Rho and Rac and disrupts the cytoskeleton of the target cells. YopO has been shown to localize at the cell plasma-membrane. By transfection of YopO-EGFP hybrid proteins into HEK293T cells, we demonstrated that the chaperone-binding domain (CBD) coincides with the membrane localization domain of YopO. Nevertheless, the CBD was not needed for the kinase activity of YopO. By ultracentrifugation, we also showed that the CBD causes YopO aggregation in the bacteria, when SycO does not cover it. Further, we show that the CBD of YopE and YopT also caused aggregation in the bacteria in the absence of SycE and SycT respectively. YopE, YopT and T3S effectors in other systems also act at the membrane of the eukaryotic host cell. We propose a new hypothesis concerning the role of T3S chaperones. The sub-cellular localization domain of effectors is aggregation-prone and creates the need for a chaperone inside bacteria. We propose that masking such aggregation-prone localization domains may be a general function for type III effector chaperones
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