182 research outputs found
Expression analysis of protein inhibitor of activated STAT (PIAS) genes in IFNβ-treated multiple sclerosis patients [Corrigendum]
No full textTaheri M, Azimi G, Sayad A, et al. J Inflamm Res. 2018;11:457–463.On page 457, Author list and Correspondence, the last author’s name was misspelt. The correct name is Soudeh Ghafouri-Fard.Read the original articl
Regional Spatial Organization with Respect to Goods Flow Network in South Alborz Region
No full textOne the most important issue in urban and regional planning and geographic debate is space and it’s changes in time. Space defined as process of different dimensions like economic, social, cultural, environmental ones, and that has a different vision so space which is a combined product of a lot of actors. In regional scale space, that is the product of relational process, creates different spatial structure like concentration, disperse and semi-disperse. Thereby dominant flow like goods, population, information, and so on are basic leverage of spatial structure change in regional scale. The aim of this paper was the analysis of South Alborz Region land scape with emphasis of goods flow in the three periods of 1997, 2007 and 2017. The research method was based on the fundamental and applicable type, and in terms of aim it is analytical-descriptive. Data collection method is documentary like statistic center data (industrial corporation, transportation, …) and paper and books. Arc GIS software and UCINET and NETDRAW were used to analyze the spatial structure and flow network. Based on the result obtained in Tehran centrality and power in spatial structure and in flow and outflow, evidence indicates that some new center emerge and absorb the saturated element of Tehran
Isolation of resonance in acoustic backscatter from elastic targets using adaptive estimation schemes
No full textThe problem of underwater target detection and classification from acoustic backscatter is the central focus of this paper. It has been shown that at certain frequencies the acoustic backscatter from elastic targets exhibits certain resonance behavior which closely relates to the physical properties of the target such as dimension, thickness, and composition. Several techniques in both the time domain and frequency domain have been developed to characterize the resonance phenomena in acoustic backscatter from spherical or cylindrical thin shells. The purpose of this paper is to develop an automated approach for identifying the presence of resonance in the acoustic backscatter from an unknown target by isolating the resonance part from the specular contribution. An adaptive transversal filter structure is used to estimate the specular part of the backscatter and consequently the error signal would provide an estimate of the resonance part. An important aspect of this scheme lies in the fact that it does not require an underlying model for the elastic return. The adaptation rule is based upon fast Recursive Least Squares (RLS) learning. The approach taken in this paper is general in the sense that it can be applied to targets of unknown geometry and thickness and, further, does not require any a priori information about the target and/or the environment. Test results on acoustic data are presented which indicate the effectiveness of the proposed approach.The work of M. R. Azimi-Sadjadi was supported by the ASEE-ONR program under the High Area Rate Recon. Project. The work of J. Wilbur and G. J. Dobeck was supported by the ONR
1938 revisited? Should doors open wider to Syrian refugees?
No full textDoes it seem that every time the world watches refugees flee violence and persecution while politicians claim their country can\u27t possibly take in asylum seekers, we lamentingly claim that the world will never again turn its back on these people.
And yet the next time we seem people streaming out of a war zone with nothing but their families and the shirts on their back we forget the promise we made the last time this happened?
For a world that promised \u27Never Again\u27 after World War II, how much have we actually learned from the handling of refugee crises of the past? Are we making the same mistakes over and over again?
Do you see echoes of the treatment of Jews fleeing the Holocaust in government rhetoric about refugees from Syria and Iraq? And if so, what explains this short-sightedness?
Guests
Dai Le, Founder of DAWN (Diverse Australasian Women’s Network)
Professor Klaus Neumann, Historian at Swinburne University and author of Across the Seas: Australia\u27s Response to Refugees: A History
Akram Azimi, Sociologist at the University of Western Australia and 2013 Young Australian of the Yea
Wave-Induced Currents Within Mangrove Forest
No full textMangroves are tidal trees commonly observed along the sheltered shorelines of most tropical (from equator to 23.5° North and South latitude) and few subtropical (23.5° to 40° North and South latitude) countries. These plants are adapted to loose wet soils, saline habitats and periodic tidal submergence. With more attention paid into the approach of building with nature, natural coastal defence strategies are gaining more importance as an asset in addressing the coastal squeeze that is prevalent not only in urban areas, but also in agriculture and industrial areas that are located along the coastline. Mangroves are receiving more attention due to their coastal protective role against wave and hydrodynamic forcings as well as their ability to adapt to sea level rise. Mangrove vegetation attenuates and damps the hydrodynamics forcings by providing obstacles to the flows and creating drag. To date and to the knowledge of the author, no study has been conducted on interaction of the wave-induced currents with mangrove vegetation. This lack of relevant studies may be due to the fact that mangrove forests and the foreshore in front of the mangroves are usually of very gently sloping bed (varying in order of 1:300 to 1:1500). This means that in order to conduct physical model experiments to study wave-induced current within a mangrove forest, a very large wave basin is required in order to conduct modelling without using a very large scale factor difference between prototype and model. This is to ensure that the relevant processes are representing prototype as closely as possible, as well as to be measureable. Numerical modelling of the interaction of wave-induced current with mangrove vegetation is yet to be conducted due to the lack of measured data for validation, both field as well as experimental measurements. An experiment by Hulsbergen (1973) was selected as validation data for current study. The main objective of the study is to understand the difference of nearshore processes for (stationary) tidal gradient-driven and oblique wave-driven current for both with and without mimic mangrove vegetation. The scope of the study involves desktop analysis of the main validation data and other relevant and similar experiments, assessment of reliability of Delft3D for the study, validation against measured data, and simulation of various hydraulic conditions for condition with mangrove forest. Among questions answered in this study are the extent of wave-induced longshore current damping within mangrove forest, the significance of wave-induced longshore current within mangrove forest, the effects of bed slope and mangrove density on wave-induced current and the extent of model’s reliability for current study. It was shown that the damping of wave-induced longshore current is more than 80% and the contribution of waveinduced current to the total velocity can be more than 70%. Of course, both of the above was specific to the bathymetry, mangrove properties and hydraulic conditions specified within current study. Furthermore, it was shown that bed slope and mangrove density affect wave-induced longshore current within the mangrove forest. It was also found that current model setup has its limitations.Civil Engineering | Hydraulic Engineering | Coastal Engineerin
Change in Attitude in Renal Function in Major Beta Thalassemia
No full textThalassemia is a multisystemic disease in the field of hemolysis and chronic anemia caused by the erythropoietic disorder. The severe effects of iron overload from continuous blood transfusion iron chelators side effects, and involvement of multiple organs in thalassemias such as heart failure, liver, and endocrine dysfunction can all affect kidney function. Although there has been much debate about changes in renal function in thalassemia for many years, the presence of hyperfiltration and ultimately, decreased renal function in almost all studies. It seems for the researchers to look beyond kidney function in a thalassemia perspective, because of secretory biomarkers of proximal tubular renal cells that are sensitive to pathologic agents, which may be a good indicator of the courses of treatment and prognosis of patients. Future studies will be sooner or later.
*Corresponding Author: Malihe Najafpour; Email: [email protected]
Please cite this article as: Malaki M, Najafpour M, Talebi M, Azimi A. Change in Attitude in Renal Function in Major Beta Thalassemia. Arch Med Lab Sci. 2020;6:1-5 (e24). https://doi.org/10.22037/amls.v6.3305
On the classes of hereditarily Banach spaces
No full textsummary:Let denote a specific space of the class of Banach sequence spaces which were constructed by Hagler and the first named author as classes of hereditarily Banach spaces. We show that for the Banach space contains asymptotically isometric copies of . It is known that any member of the class is a dual space. We show that the predual of contains isometric copies of where . For it is known that the predual of the Banach space contains asymptotically isometric copies of . Here we give a direct proof of the known result that contains asymptotically isometric copies of
Continuous Immiscible Nitrogen and WAG Injection into Bentheimer Sandstone
No full textA series of core-flood tests were performed to evaluate the EOR potential of some immiscible N2 injection schemes. Injections were conducted either in a (1) continuous mode or (2) water-alternating-gas (WAG) mode into Bentheimer sandstone cores previously saturated with model synthetic oil. Furthermore, CT imaging has been utilized in some tests to visualize the flow and to obtain the saturation profile. The CT-obtained saturation profile was consistent with the volumetric measurements. Injection strategies resulted in considerable oil recovery factors relative to oil initially in place (OIIP), but the values were different in each scheme. Three of the continuous N2 injections in a secondary mode, starting after the primary drainage stage, led to the recoveries of 48.7 %, 49.6 % and 50.8 % for 16.5 injected PV. The aforementioned tests differed in back pressures with higher back pressures resulting in higher recoveries. Test 4, water flooding followed by N2 flooding resulted in an ultimate recovery of 52.6 %, 17.1 % of which was due to gas injection. Test 5, N2 WAG with a WAG ratio of nearly 1:6 yielded the highest recovery among all concluding with an ultimate recovery of 59.0 %. Mechanism for to oil recovery by gas injection is elaborated in view of the obtained experimental results and based on the concepts of two- and three-phase flow. Implications of the different injection schemes are discussed.Civil Engineering and GeosciencesGeoscience & EngineeringPetroleum EngineeringC24B7
Evaluation of the effect of soybean diet on interferon-α-induced depression in male mice
No full textObjective: Interferon-α (IFN) therapy can cause depressive symptom which may lead to drug discontinuation. By interfering with tryptophan pathway, the available level of tryptophan required for serotonin synthesis decreases which could be related to depression. The aim of this study was to evaluate whether soybean diet could improve IFN-induced depression. Materials and Methods: Male mice weighing 28±3 g were used in the forced swimming test (FST) as an animal model of depression; also, locomotor activity was recorded. IFN 16×105 IU/kg was injected subcutaneously for 6 days. Animals were fed with regular diet or soybean diet at 3 concentrations throughout the experiment. Fluoxetine was the reference drug. To check whether the tryptophan content in the soy bean diet was effective, a group of animals was injected with a single dose of tryptophan on the test day. Results: IFN-α increased the immobility time in the FST (192 sec ± 5.4), that denotes depression in mice. Soybean diets caused less immobility that was more profound with 50% soybean (26.4 sec ± 6). This diet overcame the depression caused by IFN in the FST (54 sec±18). This result was parallel with that of tryptophan injected to animals (38 sec±17). All the animals showed normal locomotor activity. Conclusion: For the first time, we showed that soybean diet could counteract with depression caused by IFN-α. Since tryptophan therapy had similar effects, possibly the tryptophan content of soybean had induced the serotonin synthesis. Thus, not only less harmful kynurenine was produced but also more serotonin was available in the brain to overcome depression. However, this interpretation needs further evaluations
Evaluation of the effect of soybean diet on interferon-alpha-induced depression in male mice
No full textObjective: Interferon-alpha (IFN) therapy can cause depressive symptom which may lead to drug discontinuation. By interfering with tryptophan pathway, the available level of tryptophan required for serotonin synthesis decreases which could be related to depression. The aim of this study was to evaluate whether soybean diet could improve IFN-induced depression.& para;& para;Materials and Methods: Male mice weighing 28 +/- 3 g were used in the forced swimming test (FST) as an animal model of depression; also, locomotor activity was recorded. IFN 16x10(5) (IU/kg was injected subcutaneously for 6 days. Animals were fed with regular diet or soybean diet at 3 concentrations throughout the experiment. Fluoxetine was the reference drug. To check whether the tryptophan content in the soy bean diet was effective, a group of animals was injected with a single dose of tryptophan on the test day.& para;& para;Results: IFN-alpha increased the immobility time in the FST (192 sec +/- 5.4), that denotes depression in mice. Soybean diets caused less immobility that was more profound with 50 soybean (26.4 sec +/- 6). This diet overcame the depression caused by IFN in the FST (54 sec +/- 18). This result was parallel with that of tryptophan injected to animals (38 sec +/- 17). All the animals showed normal locomotor activity.& para;& para;Conclusion: For the first time, we showed that soybean diet could counteract with depression caused by IFN-alpha. Since tryptophan therapy had similar effects, possibly the tryptophan content of soybean had induced the serotonin synthesis. Thus, not only less harmful kynurenine was produced but also more serotonin was available in the brain to overcome depression. However, this interpretation needs further evaluations
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