1,721,072 research outputs found
Mein digitaler Zwilling: Mathematische Computermodelle des Herzens (Dr.-Ing. Axel Loewe)
Dr.-Ing. Axel Loewe, Leiter der KIT-Nachwuchsgruppe Computational Cardiac Modeling am
Institut für Biomedizinische Technik, beschreibt in seinem Vortrag welche Möglichkeiten mathematische Computermodelle des Herzens für die Diagnose und Therapie von Herzkrankheiten eröffnen.
Der Vortrag wurde am 7. Februar 2022 im Rahmen der Veranstaltung "KIT im Rathaus - Das KIT-Zentrum MathSEE stellt sich vor" live gestreamt
Pace-and-Drive of the Human Sinoatrial Node – A Preliminary Computational Investigation
The sinoatrial node (SAN) is the natural pacemaker of
our heart. How this small tissue is able to drive a
remarkably larger number of intrinsically quiescent atrial
cells is still debated; a computational investigation of the
underlying mechanisms can help to better understand the
SAN’s ability to pace-and-drive the surrounding atrium.
Aim of this work is to elucidate how the human SAN
action potential can successfully be captured by and
propagate into the surrounding atrial tissue.
The Fabbri et al. and the Courtemanche et al. models
were used to describe the human SAN and atrial cells,
respectively. The behaviour of two coupled regions was
investigated varying the interregional conductivity (σ)
and relative size. Simulations showed that it requires at
least an isopotential SAN region 2.85 times wider than
the atrial one. A 1D strand of homogeneously coupled
SAN and atrial elements was used to identify an interval
for σ showing pace-and-drive behaviour (100 SAN vs 100
atrial elements) and to investigate the source-sink
interplay (10, 50 or 100 SAN elements vs 100 atrial
elements). The 1D strand showed pace-and-drive
behaviour for σ = 0.08 − 36 S/m; a stronger source,
with a higher number of SAN elements, led to a wider σ
range that allowed pace-and-drive behaviour, whereas a
stronger sink did not affect the behaviour of the tissue.
This preliminary work shows the ability of a small
human SAN region to pace-and-drive the surrounding
atrial tissue. Further investigations are needed to explore
different conductivity configurations, including spatial
gradients
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
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