930 research outputs found
Meat quality assessment of raw meat from two Mediterranean autochthonous pig breeds reared in sustainable conditions
No full textThe sustainability of livestock farming in relation to global anxiety about climate change and the quality of agro-ecosystem services has become a fundamental issue for the world and the scientific community. Many aspects of meat quality are related to genotype, sex, and age of the animals as well as the production system. In Mediterranean countries, farmers in marginal areas engage in environmentally friendly production systems using native genotypes that are well adapted to the environment and are able to exploit the feed resources available on the territory. The black pig
breeds are autochthonous in many countries and reared in the interior of the Mediterranean region. Although in Italy, the black pig breeds have been studied and analysed for years, and have been divided in different populations, in Greece, there is a lack of information about the productive performance of black pigs. The current study, funded by the GREEN FUND GREECE no.003141, aimed to evaluate the effect of genotype on the quality parameters, the chemical composition and fatty acid profile on the Longissisum lumborum muscle in pig slaughtered at 9 and 12 months of age. For this purpose, 20 piglets were selected from 2 pig farms (1 Greek and 1 Italian) and divided into 4 experimental groups (5 animals per group): E9-Greek breed, slaughtered at the age of 9 months, E12- Greek breed, slaughtered at 12 months of age, I9 Italian breed, slaughtered at 9 months of age, and I12 Italian breed, slaughtered at 12 months of age. Pigs were slaughtered at a licensed abattoir in their country of birth and meat quality analyses were carried out at the University of Bari. The preliminary results show that the E12 meat is less dark with better values of tenderness than I12. The genotype did not influence the chemical composition of 9 months pigs, but on the other hand the I12 have lower protein content and intramuscular fat than E12. As far as the meat fatty acid composition is concerned, the results show a higher percentage of SFA but a lower of MUFA in Italian groups. The concentration of n-3 and n-6 was higher in E9 and E12 than the Italian groups. The meat health indexes were not influenced by genotype but were influenced by age of slaughter. This trial could be a first step to evaluate meat characteristics of Greek black pigs and, therefore, a tool to exploit the diversity of production systems and to raise awareness of the relevance and value of this animal genotype
Factors affecting trust and communication in global virtual teams
No full textAuthor Georgios GousiasMasterarbeit Universität Linz 2022Arbeit auf den öffentlichen PCs in den Bibliotheken der JKU+Medizin abrufba
Factors affecting trust and communication in global virtual teams
No full textAuthor Georgios GousiasMasterarbeit Universität Linz 2022Arbeit auf den öffentlichen PCs in den Bibliotheken der JKU+Medizin abrufba
Meat quality in autochthonous Mediterranean pig breeds reared in organic production systems
No full textBlack pig breeds are autochthonous populations present in many Mediterranean
countries, reared on sustainable production systems as they can exploit the feed
resources available on the territory. While in Italy the black pig breeds have been
thoroughly studied, in Greece there is still lack of information about the
productive performances of this animal. This is a comparative study aiming at
investigating on the carcass traits and meat quality features of the autochthonous
Greek Black Pig and Italian Apulo-Calabrese black pig reared under organic
production systems, typical of the rural areas of the two countries, on the quality
parameters, chemical composition and fatty acid pro fi le of the Longissisum
lumborum muscle. A total of 40 pigs were used, 20 for each genotype, within
each genotype two sub-groups were made and slaughtered at 9 or 12 months of
age, respectively. When slaughtered at 12 months of age, meat from the Greek
pig was brighter and more tender than the Apulo-Calabrese, while the chemical
composition from the Italian breed showed a lower protein and intramuscular fat
content than the Greek one. A higher percentage of Saturated Fatty Acids (SFA),
total n-3 and n-6 fatty acids in turn of a lower amount of Mono Unsaturated Fatty
Acids (MUFA) was found in meat from both the Greek groups. This trial may be
considered as a fi rst step to evaluate meat characteristics of the autochthonous
Greek black pig and, therefore, a tool to increase awareness of this local
genotype and its exploitation
Der griechische Gelehrte Georgios Zachariadis und sein Beitrag zum slawischen Schrifttum im 19. Jahrhundert
No full textAmong the Greek scholars who lived during the 19th century in the north-eastern Balkans, and also in Central Europe, and by their work contributed to the spiritual development of the Balkan Slavs, pride of place must be given to Georgios Zachariadis. Unfortunately, however, no detailed monograph on Zachariadis exists. On this account the problems that arise concerning the life and activities of this Greek scholar are still many and varied. In his study the author tries to fill one part of this lacuna. At the beginning of the work the following are examined, on the basis of new historical evidence: the date and place of Georgios Zachariadis’ birth, his studies and tenure as teacher in the Greek school at Zemun, the Serbian school at Šabac, and the Greek school in Vienna. The author continues his study by analyzing the various works of Zachariadis, which are written on Old Church^Slavonic, and the translations this Greek scholar made from Greek into Old Church Slavonic. Finally, the extent of Georgios Zachariadis’ contribution to Slavonic letters is made clear
The political program of Hellenism in Turkey
No full textTitle: Tό πoλιτικόν πρόγραμμα τοῦ Έλληνισμοῦ έν Tουρκία (The political program of Hellenism in Turkey) Originally published: as a leaflet in Istanbul, 1912 Language: GreekThe excerpts used are from the original which can be found at the ‘Ion Dragoumis archive’ in the Gennadion Library in Athens, pp. 7–9, 11–13, 24–25. About the author Georgios Boussios [1876, Grevena (Ottoman Macedonia) – 1929, Athens]: activist, politician and journalist. He was born into a well-off family of merchants. He c..
Correction: Do chemistry and rheology follow the same laboratory ageing trends in bitumen?
No full text Correction to: Materials and Structures (2022) 55:146 https://doi.org/10.1617/s11527-022-01986-w The article “Do chemistry and rheology follow the same laboratory ageing trends in bitumen?”, written by Georgios Pipintakos, Caitlin Lommaert, Aikaterini Varveri and Wim Van den bergh, was originally published in volume 55, issue 5, ID 146 without open access. With the society's decision to grant Open Choice the copyright of the article changed in February 2023 to © The Author(s) 2022 and the article is forthwith distributed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0. Open access funding enabled and organized by RILEM.Pavement Engineerin
The evaluation of the effect of PAMAM dendrimers in the solubility of lmiquimod
No full textCharles University, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Technology Supervisor: Dr. Georgios Paraskevopoulos, Ph.D. Consultant: Eleni Panoutsopoulou Author: Mgr. Thu Thao Truongová Title of the thesis: The evaluation of the effect of PAMAM dendrimers in the solubility of Imiquimod Dendrimers are highly branched polymeric compounds with defined properties. They are used as a nanoparticle delivery system, however concurrently they have significant potential in enhancing the solubility of poorly water soluble drugs. Dendrimers work as drug carriers either by encapsulating the drug in their branched internal structure or they create interactions with the drug in the outer layer via terminal functional groups. The aim of this work was to evaluate the effect of polyamidoamine (PAMAM) dendrimers on the solubility of the hydrophobic drug imiquimod. Solutions of zero, first, second and third generation dendrimers were prepared at six different concentrations. During the experiment, the pH of the solutions was measured before and after addition of excess amount of imiquimod. Subsequently, analysis was performed by high-performance liquid chromatography. The measured results show that the first generation of PAMAM dendrimers is able to increase the solubility of imiquimod in...C2-Internal Abstrakt Univerzita Karlova, Farmaceutická fakulta v Hradci Králové Katedra Farmaceutické technologie Školitel: Dr. Georgios Paraskevopoulos, Ph.D. Konzultant: Eleni Panoutsopoulou Autor: Mgr. Thu Thao Truongová Název rigorózní práce: Hodnocení účinku PAMAM dendrimerů na rozpustnost imiquimodu Dendrimery jsou velmi rozvětvené polymerické sloučeniny s definovanými vlastnostmi. Používají se jako nanočásticový distribuční systém, zároveň však mají významný potenciál v oblasti zvyšování rozpustnosti ve vodě špatně rozpustných léčiv. Dendrimery fungují jako nosiče léčiva buď na principu enkapsulace molekuly léčiva ve své rozvětvené vnitřní struktuře nebo vytvářejí interakce s léčivem ve vnější vrstvě skrze terminální funkční skupiny. Cílem této práce bylo zhodnotit účinek polyamidoaminových (PAMAM) dendrimerů na rozpustnost hydrofobního léčiva imiquimod. Postupně byly připraveny roztoky dendrimerů nulté, první, druhé a třetí generace v šesti různých koncentracích. Během experimentu se měřilo pH roztoků před a po přidání nadbytečného množství imiquimodu. Následně byla provedena analýza vysokoúčinnou kapalinovou chromatografií. Z naměřených výsledků použitých generací PAMAM dendrimerů vyplývá, že první generace těchto dendrimerů dokázala nejvíce zvýšit rozpustnost imiquimodu ve vodném prostředí. Do...Department of Pharmaceutical TechnologyKatedra farmaceutické technologieFaculty of Pharmacy in Hradec KrálovéFarmaceutická fakulta v Hradci Králov
Effect of PAMAM dendrimers on the solubility and the skin permeation of flufenamic acid
No full textUniverzita Karlova, Farmaceutická fakulta v Hradci Králové Katedra Farmaceutické technologie Školitel: Dr. Georgios Paraskevopoulos, Ph.D. Autor: Lenka Novotná Název diplomové práce: Vliv PAMAM dendrimerů na rozpustnost a kožní permeaci kyseliny flufenamové Kyselinu flufenamovou (FFA) patří do skupiny nesteroidních antiflogistik. Léčiva ze skupiny nesteroidních antiflogistik jsou nejhojněji užívané léky na celém světě. Škála použití je velmi rozsáhlá. Účinek léčiv je protizánětlivý, proti bolesti a teplotě. Problém jejich použití, zejména perorálně, tkví ve velkém množství nežádoucích účinků. Pro snížení výskytu nežádoucích účinků lze FFA podávat v lokální formě. Přestup látek přes kožní bariéru je obtížný. Látky musí splňovat určitá kritéria, aby molekuly byly schopné penetrovat přes hydrofilní a zároveň hydrofóbní část lamelární lipidové multivrstvy obsažené v části epidermis. Pro zlepšení rozpustnosti FFA ve vodě bylo využito výhodných vlastností poly(amidoaminových) (PAMAM) dendrimerů. PAMAM dendrimery jsou sférické makromolekuly s velmi dobře organizovanou strukturou. Fungují i jako akceleranty kožní permeace neboli kožní enhancery. Skupina těchto pomocných látek přechodně snižuje propustnost kožní bariéry a usnadňuje transdermální podání léčiv. Mezi další výhodné vlastnosti patří výborná...Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Technology Supervisor: Dr. Georgios Paraskevopoulos, Ph.D. Author: Lenka Novotná Title of the thesis: Flufenamic acid (FFA) belongs to the group of non-steroidal anti-inflammatory drugs. Medicines from the group of non-steroidal anti-inflammatory drugs are the most widely used drugs worldwide. The range of uses is very extensive. The effect of the drugs is anti- inflammatory, they also serve against pain and fever. The problem with their use, especially orally, lies in the large number of side effects. To reduce the incidence of adverse effects, FFA can be administered topically. The transfer of substances through the skin barrier is demanding. The substances must meet certain criteria so that the molecules are able to penetrate through the hydrophilic and at the same time hydrophobic part of the lamellar lipid multilayer contained in the epidermis. To improve the solubility of FFA in water, we used the advantageous properties of poly(amidoamine) (PAMAM) dendrimers. PAMAM dendrimers are spherical macromolecules with a very well-organized structure. They work well as skin permeation accelerators or skin enhancers. A group of these excipients temporarily reduces the skin barrier and facilitates the transdermal...Department of Pharmaceutical TechnologyKatedra farmaceutické technologieFarmaceutická fakulta v Hradci KrálovéFaculty of Pharmacy in Hradec Králov
Effect of selected imidazolium ionic liquids on the permeability of human skin during their co-application with model compounds
No full textUniverzita Karlova, Farmaceutická fakulta v Hradci Králové Katedra Farmaceutické technologie Školitel: Dr. Georgios Paraskevopoulos, Ph.D. Autor: Denisa Trávníčková Název diplomové práce: Vliv vybraných imidazoliových iontových kapalin na permeabilitu lidské kůže při jejich ko-aplikaci s modelovými sloučeninami Transdermální aplikace je vzhledem ke snadné aplikaci, vyhnutí se first - pass efektu a velkému povrchu kůže vhodná cesta podání léčivé látky. Hlavní bariérou, která omezuje přístup většiny látek do hlubších vrstev kůže a do systémové cirkulace je stratum corneum. Permeaci léčiv kůži navíc ovlivňuje řada faktorů, zejména fyzikálně-chemické vlastnosti látky. Struktura a funkce SC je zásadní pro udržení kožní bariéry a nalézt způsob k překonání bariérových vlastností kůže, který by nepoškodil kůži, je obtížné. Použití iontových kapalin jako enhancerů kožní penetrace představuje nový směr ve vývoji dermatologických a farmaceutických přípravků. Struktura iontových kapalin umožňuje nespočetnou kombinaci kationtů a aniontů, které by teoreticky mohly vést k syntéze iontových kapalin s požadovanou vlastností či aplikací. Tato práce přispívá k pochopení vlivu dvou imidazolových iontových kapalin na permeační profil modelových látek - theofylinu a sodné soli diklofenaku, při aplikaci na lidskou kůži...Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Technology Supervisor: Dr. Georgios Paraskevopoulos, Ph.D. Author: Denisa Trávníčková Title of the thesis: Effect of selected imidazolium ionic liquids on the permeability of human skin during their co-application with model compounds Transdermal application is due to the ease of application, avoiding the first-pass effect and the large surface area of the skin make it a suitable route of administration. The stratum corneum is the main barrier that limits the access of most substances to the deeper layers of the skin and to the systemic circulation. In addition, the permeation of drugs through the skin is influenced by a number of factors, particularly the physicochemical properties of the substance. The structure and function of the SC is critical to the maintenance of the skin barrier, and finding a way to overcome the barrier properties of the skin that does not damage the skin is difficult. The use of ionic liquids as skin penetration enhancers represents a new direction in the development of dermatological and pharmaceutical products. The structure of ionic liquids allows for a myriad of combinations of cations and anions that could theoretically lead to the synthesis of ionic liquids with desired properties...Department of Pharmaceutical TechnologyKatedra farmaceutické technologieFarmaceutická fakulta v Hradci KrálovéFaculty of Pharmacy in Hradec Králov
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