5 research outputs found
Planning for operational crowd management
No full textPeople are becoming more mobile and enterprising. They go to events or go shopping, which means they walk and they are not alone. Especially in larger cities or at events it can get very crowded, which is accompanied by risks. To guarantee the safety of pedestrians, crowd management has to be applied. Knowledge about crowd management is documented in literature and handbooks, which can be time-consuming and lengthy to read for crowd managers and might not be read for those reasons. Therefore the numerous forms and types of knowledge have been used to develop a decision support tool for the planning of operational crowd management. The developed decision support tool estimates which risks are present in the situation at hand and gives an advice on the application of crowd management measures and a suitable crowd monitoring system.Transport and PlanningTransport & PlanningCivil Engineering and Geoscience
Dynamic Named Entity Recognition
No full textInternational audienceNamed Entity Recognition (NER) is a challenging and widely studied task that involves detecting and typing entities in text. So far, NER still approaches entity typing as a task of classification into universal classes (e.g. date, person, or location). Recent advances in natural language processing focus on architectures of increasing complexity that may lead to overfitting and memorization, and thus, underuse of context. Our work targets situations where the type of entities depends on the context and cannot be solved solely by memorization. We hence introduce a new task: Dynamic Named Entity Recognition (DNER), providing a framework to better evaluate the ability of algorithms to extract entities by exploiting the context. The DNER benchmark is based on two datasets, DNER-RotoWire and DNER-IMDb. We evaluate baseline models and present experiments reflecting issues and research axes related to this novel task
Vascular endothelial growth factor and diabetic nephropathy
No full textThe field of vascular endothelial growth factor (VEGF) has recently witnessed a surge of research into its role in diabetic kidney disease. Based on its credentials as a potent inducer of vasopermeability and angiogenesis, podocyte-derived VEGF is believed to participate in the glomerular capillary hyperpermeability of macromolecules that potentially underlies the pathogenesis of diabetic albuminuria. The evidence for VEGF's role is relatively straightforward in animal models of diabetes, establishing that VEGF is upregulated in the diabetic kidney, that VEGF alone reproduces some aspects of diabetic glomerulopathy, and that antagonism of VEGF attenuates diabetic albuminuria and other associated features of the podocytopathy. However, the promise shown in the animal studies has not carried over as convincingly into the realm of human studies, as some investigators find a negative or no relationship between VEGF and diabetic nephropathy, whereas others find a positive correlation between the two. If VEGF does play a role in diabetic renal disease, its observed effects and known mechanisms seem to point squarely at the podocyte as a central target of the maladaptive VEGF overactivity. © Current Medicine Group LLC 2008.Al-Kateb H, 2007, DIABETES, V56, P2161, DOI 10.2337-dbo7-0376; Baba T, 2004, DIABETIC MED, V21, P292, DOI 10.1111-j.1464-5491.2004.01094.x; Baelde HJ, 2004, AM J KIDNEY DIS, V43, P636, DOI 10.1053-j.ajkd.2003.12.028; Baelde HJ, 2007, KIDNEY INT, V71, P637, DOI 10.1038-sj.ki.5002101; Bailey E, 1999, J CLIN PATHOL, V52, P735; Belteki G, 2005, NUCLEIC ACIDS RES, V33, DOI 10.1093-nar-gni051; Bortoloso E, 2004, EUR J ENDOCRINOL, V150, P799, DOI 10.1530-eje.0.1500799; Braun L, 2001, LIFE SCI, V69, P2533, DOI 10.1016-S0024-3205(01)01327-3; Buraczynska M, 2007, NEPHROL DIAL TRANSPL, V22, P827, DOI 10.1093-ndt-gfl641; Cha DR, 2004, J ENDOCRINOL, V183, P183, DOI 10.1677-joe.1.05647; Chen S, 2004, DIABETES, V53, P2939, DOI 10.2337-diabetes.53.11.2939; Chiarelli F, 2000, DIABETIC MED, V17, P650, DOI 10.1046-j.1464-5491.2000.00350.x; Cipriani R, 2004, DIABETES NUTR METAB, V17, P90; Cooper ME, 1999, DIABETES, V48, P2229, DOI 10.2337-diabetes.48.11.2229; De Vriese A, 2001, J AM SOC NEPHROL, V12, P993; Eremina V, 2007, NEPHRON PHYSIOL, V106, P32, DOI 10.1159-000101798; Flyvbjerg A, 2002, DIABETES, V51, P3090, DOI 10.2337-diabetes.51.10.3090; Hohenstein B, 2006, KIDNEY INT, V69, P1654, DOI 10.1038-sj.ki.5000294; Honkanen EO, 2000, KIDNEY INT, V57, P2343, DOI 10.1046-j.1523-1755.2000.00094.x; Hoshi S, 2002, LAB INVEST, V82, P25; Hovind P, 2000, Kidney Int Suppl, V75, pS56; Ichinose K, 2006, DIABETES, V55, P1232, DOI 10.2337-db05-1367; Ichinose K, 2005, DIABETES, V54, P2891, DOI 10.2337-diabetes.54.10.2891; Kanesaki Y, 2005, AM J KIDNEY DIS, V45, P288, DOI 10.1053-j.ajkd.2004.09.020; Kim NH, 2004, DIABETIC MED, V21, P545, DOI 10.1111-j.1464-5491.2004.01200.x; Kim NH, 2005, KIDNEY INT, V67, P167, DOI 10.1111-j.1523-1755.2005.00067.x; Klanke B, 1998, NEPHROL DIAL TRANSPL, V13, P875, DOI 10.1093-ndt-13.4.875; Lee EY, 2004, EXP MOL MED, V36, P65; Lenz T, 2003, KIDNEY BLOOD PRESS R, V26, P338, DOI 10.1159-000073940; Lindenmeyer MT, 2007, J AM SOC NEPHROL, V18, P1765, DOI 10.1681-ASN.2006121304; McKnight AJ, 2007, J DIABETES COMPLICAT, V21, P242, DOI 10.1016-j.jdiacomp.2006.05.005; Nakagawa T, 2007, AM J PHYSIOL-RENAL, V292, pF1665, DOI 10.1152-ajprenal.00495.2006; Ray D, 2004, DIABETES, V53, P861, DOI 10.2337-diabetes.53.3.861; Santilli F, 2001, J CLIN ENDOCR METAB, V86, P3871, DOI 10.1210-jc.86.8.3871; SENGER DR, 1983, SCIENCE, V219, P983, DOI 10.1126-science.6823562; Shimada K, 2002, J DIABETES COMPLICAT, V16, P386, DOI 10.1016-S1056-8727(02)00162-9; Shulman K, 1996, J AM SOC NEPHROL, V7, P661; Singh AK, 2004, LAB INVEST, V84, P597, DOI 10.1038-labinvest.3700082; SISON K, 2005, 38 ANN AM SOC NEPHR; Sung SH, 2006, J AM SOC NEPHROL, V17, P3093, DOI 10.1681-ASN.2006010064; Tsuchida K, 1999, DIABETOLOGIA, V42, P579, DOI 10.1007-s001250051198; Wang A, 2007, AM J PHYSIOL-RENAL, V293, pF1657, DOI 10.1152-ajprenal.00274.2007; Wang ZW, 2005, DIABETES, V54, P2328, DOI 10.2337-diabetes.54.8.2328; Weis SM, 2005, NATURE, V437, P497, DOI 10.1038-nature03987; Wilkinson L, 2007, J AM SOC NEPHROL, V18, P1697, DOI 10.1681-ASN.2006091012; Yamamoto Y, 2004, DIABETES, V53, P1831, DOI 10.2337-diabetes.53.7.1831; Yang BM, 2003, J DIABETES COMPLICAT, V17, P1, DOI 10.1016-S1056-8727(02)00181-2; Zdarska DJ, 2007, J INT MED RES, V35, P374; Zeng LX, 2005, FASEB J, V19, P1845, DOI 10.1096-fj.05-4240fje; Ziyadeh Fuad N, 2008, Curr Diabetes Rev, V4, P39, DOI 10.2174-15733990878350237031292
