186,165 research outputs found
Thromboembolic tendency (TE) in IBD (Inflammatory bowel disease) patients.
No full textThe acronym IBD identifies the ulcerative colitis (URC), Crohn's disease (CD) and
the undeterminate colitis (UC) 7. Inflammatory bowel diseases are characterized
by variegated etiopathogenesis, probably autoimmune. They have in common a
histological damage of a granulomatous/ulcerative kind and also the same
manifestations which includes the alternation of remissions and exacerbations 1.
They have a remarkable familiarity (13.5%) although it is more evident in CD than
in URC. The incidence of IBD varies according to different geographical areas but
with a steady increasing trend above all in CD and the diffusion seems to be
linked to genetic factors (association with HLA-A2 and B 18) and to geographical
factors. Today the etiopathogenesis is still debated. The latest theories seem to
confirm an autoimmune genesis. IBD show a remarkable tendency in developing
secondary remote manifestations in a different location from the intestinal one:
extraintestinal manifestations (EM). They can appear simultaneously with the
primitive intestinal manifestation or they can precede or follow after years.
According to the most reliable etiopathogenetic hypothesis, EM give rise to
"metastasizations" of autoantibodies activated in the bowel from the "ideational
intestinal brain"; once the autoantibodies are activated, they are able to attack
any organ, tissue or system causing damage directly or mediated. In support of
this theory there is the evidence that almost all EM regress with a
cortison-based/immunosuppressant treatment. In literature we have descriptions of
the extraintestinal remissions of symptoms after total proctolectomia and
ileo-anal pouch. Among EM we find following manifestations: hepatobiliary,
osteoarticular, muscular, dermatological, stomatological, ophthamological,
gynaecological, urological, metabolic, perianal etc. Recently another
manifestation has appeared which consists in a remarkable thromboembolic tendency
(TE) in IBD patients. TE and IBD are an important field of research as TE occurs
in young patients aggressively causing significant morbidity (stroke, retinal
vascular occlusive thrombus deposition in cerebral, retinal and mesenteric
vessels, massive pulmonary embolism). Several studies describe thrombosis in
venous and arterial district in IBD patients as 4% but according to autopsy
studies the percentage is more than 30% 2. Among the causes of the TE disease we
have: thrombocytosis, increase of the coagulation factors, mutation of V factor
of Laiden 8, hyperhomocysteinemia (due to the combined deficit of
methylene-hydrofolate-tetra reductase (MTHFR), B12 vitamin and folate) observed
mutation of MTHFR gene in some IBD patients. Finally, surgery determines an
additional TE risk in these patients compared to non-IBD patients who have the
same operation. Some studies describe mortality of 1-1,2% after restorative
proctolectomia due to TE complications (pulmonary-cerebral and mesenteric
district
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Dr. Edward P. Wimberly, ITC, July 2011
No full textThis video is a conversation with Dr. Edward P. Wimberly. Dr. Wimberly talks about his book, "No Shame in Wesley's Gospel: A Twenty-First Century Pastoral Gospel". Brad Ost, AUC Woodruff Library, is the interviewer
Author Rights and Scholarly Publishing
No full textOriginally posted at
http://blog.library.gsu.edu/2014/10/24/author-rights-and-scholarly-publishing/</p
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