175 research outputs found
Postmodern elements in Mirza Athar Beg's novel Sifir Se Eyk Tak
Postmodernizm 1960'lardan günümüze kadar olan dönemi belirtir. Postmodernizmin önemli anları arasında soğuk savaş ve sonrasındaki etkiler, çok kültürlülüğün veya etnik çeşitliliğin artan kabulü ve teknolojinin, özellikle televizyon ve bilgisayarların yükselişi yer alır. Toplumu derinden etkileyen bu olaylar edebiyat alanına da yansımıştır. Urdu edebiyatında Mirza Athar Beg; üstkurmaca, metinlerarasılık, parodi, pastiş ve ironi gibi postmodern unsurları romanlarında kullanan postmodern yazarlardan biridir. Yazar kullandığı dil oyunlarıyla Sıfır Se Eyk Tak adlı romanını postmodern roman estetiğine dahil etmiştir. Athar Beg, romanda kronolojik olmayan parçalı bir anlatım tarzıyla okurun ilgisini çekmektedir. Bu çalışmanın amacı, postmodernizmin belirli unsurlarının Mirza Athar Beg'in Sıfır Se Eyk Tak adlı eseri üzerindeki etkilerini incelemektir. Çalışmada, ilk olarak Urdu edebiyatının gelişim süreci ve postmodernizm kavramı ile ilgili teorik bilgiler ortaya konmaya çalışılmıştır. Daha sonra postmodern edebiyatın özellikleri detaylı bir şekilde incelenmiştir. Bu bilgiler ışığında Mirza Athar Beg'in Sıfır Se Ey Tak eserinde postmodern anlatının özellikleri açıklanmaya çalışılmıştır.The 1960s to the present are referred to as postmodernism. The cold war and its aftermath, the growing embrace of multiculturalism or ethnic diversity and the development of technology, particularly television and computers, are notable examples of postmodernism. These incidents, which had a significant impact on society, were also mirrored in literature. One of the postmodern writers in Urdu literature, Mirza Athar Beg, employs metafiction, intertextuality, parody, pastiche and irony in his works. By the use of language games, the author has incorporated his book Sıfır Se Eyk Tak into postmodern novel aesthetics. In the book, Athar Beg uses a non-chronological, fragmented narrative style to play with the reader's perception. The purpose of this study is to ascertain how postmodernism has affected the chosen work by Mirza Athar Beg. Theoretical knowledge regarding the idea of postmodernism has been made available in the study. The Characteristics of postmodern literature were then thoroughly investigated. The characteristics of postmodern expression in Mirza Athar Beg's Sıfır Se Eyk Tak have been attempted to be explained in light of this information
Mirza Athar Baig’s novel “Ghulam Bhag” and Post Colonialism Discourse : Mirza Athar Baig’s novel “Ghulam Bhag” and Post Colonialism Discourse
Ghulam Bagh is an important novel created in the Post-Colonial period in which Mirza Athar Baig has presented the intellectual and mental attitudes of this era.We can say that Post-Colonial literature refers to the literary texts that are created in the former colonies of Europe. In these writings, the background of Post-Colonialism and the background of Colonialism are presented in a literary Perspective. Post-Colonial literature shows an attempt to understand, examine and describe the feelings and experiences of those belonging to the former colonies. Mirza Athar Baig\u27s novel Ghulam Bagh was published in 2006 and six editions have been published so far. Ghulam Bagh is a masterpiece novel of fictional literature created in the former British colonial Pakistan, There are also characters living in the Post-Colonial era. Each character shows change, evolution and conflict. Ghulam Bagh is an imaginary place in terms of archeology. If we examine the title of the novel in a broader context, Ghulam Bagh is a metaphor for the desire of western nations to dominate the inferior, weak and noble races of the world. Is based on desire. In this paper, the novel will be studied in the Post-Colonial context to find out how far the author has succeeded in recovering the Colonial discourse.
 
Pursuing an Elusive Seeker of Universal Truth – the Identity and Environment of the Author of the Dabistān–i Mazāhib
Professor Athar Ali (born 18 January 1925) studied at Aligarh Muslim University 1948–53. His PhD studies were supervised by Professor Satish Chandra. In 1953 he was appointed research assistant at the university and became a Professor in 1978. He was Wilson Fellow at the Smithsonian Institute in 1986, Smuts Fellow, Cambridge, 1974–5 a nd President of the Indian History Congress in 1989. His major publications are The Mughal Nobility under Aurangzeb (Aligarh, 1966) and The Apparatus of Empire (Delhi, 1985). Sadly he died not long after this article was accepted for publication and was therefore unable to see it in print.</jats:p
Is Robotic Process Automation Important?
Abstract: With the introduction of integrated circuits (IC), technology has vastly advanced over the last few decades, and today digitalization, artificial intelligence, and machine learning are the new buzzwords that are revolutionizing the IT industry. This opens up a new realm of hyper-automation., The concept of automation has been around for a very long time. But in recent years, it’s become increasingly common to speak about Robotic Process automation, but what exactly we mean by Robotic Process automations in the world of IT What exactly do we mean by that?
Keywords: Hyper automation, Robotic Process Automation, Digitalization.
Title: Is Robotic Process Automation Important?
Author: Muhammad Fahad Athar
International Journal of Electrical and Electronics Research
ISSN 2348-6988 (online)
Vol. 10, Issue 3, July 2022 - September 2022
Page No: 1-3
Research Publish Journals
Website: www.researchpublish.com
Published Date: 18-August-2022
DOI: https://doi.org/10.5281/zenodo.7007406
Paper Download Link (Source)
https://www.researchpublish.com/papers/is-robotic-process-automation-importantInternational Journal of Electrical and Electronics Research, ISSN 2348-6988 (online), Research Publish Journals, Website: www.researchpublish.co
Identification of glutathione S-transferase inhibiting natural products from Matricaria chamomilla and biotransformation studies on oxymatrine and harmine
This thesis describes the results obtained from the phytochemical analysis of Matricaria chamomilla, and the microbial transformation of oxymatrine (85) and harmine (87), as summarized below.
1. Chemical investigation of the crude methanolic extract of Matricaria chamomilla resulted in the isolation of a new natural product, matriisobenzofuran (72), along with four known compounds: apigenin (73), apigenin-7-O-β-glucopyranoside (74), scopoletin (75), and fraxidin (76). The structures of compounds 72-76 were elucidated with the aid of extensive NMR and mass spectroscopic studies. All of the aforementioned compounds showed moderate to good inhibitory activities against glutathione S-transferase, an enzyme which has been implicated in the resistance of cancer cells to chemotherapeutic agents. These compounds were also evaluated for antioxidant activity and displayed moderate to good free radical scavenging activity. Additionally, compounds 72-76 were screened for anti-leishmanial activity. Compounds 75 and 76 were significantly active in this assay, while the remaining compounds were weakly active. In the antibacterial and antifungal assays, compounds 72-76 were not active.
2. The second part of this thesis deals with the biotransformation studies on oxymatrine (85) and harmine (87). Oxymatrine (85) was metabolized to the deoxy analogue, matrine (84) by Penicillum chrysogeneum (ATCC 9480), Cunninghamella bainieri (ATCC 9244), Cunninghamella blakesleena (ATCC 9245 and 8688A), Curvularia lunata (ATCC 12017), and Fusarium sp. In the time-based analysis of this transformation, the metabolism of oxymatrine (85) could be detected after 48 hours of incubation. Additionally, incubation of harmine (87) with Mucor plumbeus (ATCC 4740) resulted in the isolation of harmine-N-oxide (94). The biotransformed products (84 and 94) were identified using IR, UV, NMR, and mass spectroscopic techniques. Compound 94 was evaluated for its ability to inhibit the enzyme acetylcholinestrase, whose overexpression has been linked to Alzheimer’s disease, and was found to possess weaker activity than harmine (87).October 201
Synthesis and biological evaluation of benzothiazole derivatives of pyrimidines, acrylonitriles, and coumarins.
A number of benzothiazole derivatives of 2-aminopyrimidines (3a-b, 5, 6a-b, and 7), benzothiazole-3-arylacrylonitriles (10a-c), and benzothiazol-2-yl-coumarins (18a c, and 20) were synthesized by reacting benzothiazole derivatives with dicarbonyl compounds, and aromatic aldehydes. The unexpected 2-(4-methoxyphenyl)benzo[d]thiazole (14) was obtained as a unique product via the reaction of 2-aminothiophenol with ethyl 3-(4-methoxyphenyl)-2-scyanoacrylate. 2-(Benzo[d]thiazol-2-yl)-3-(4-hydroxyphenyl)acrylonitrile (10a) exhibited activity against Staphylococcus aureus. 2-(Benzo[d]thiazol-2-ylamino)pyrimidine-4,6-(1H,5H)-dione (3b) showed antibacterial activity selectivity against Corynebacterium xerosis. 2-(Benzo[d]thiazol-2-ylamino)-6-methylpyrimidin-4(3H)-one (5) showed weak anti-fungal activity against Candida albicans.Source type: Electronic(1
Identification of α- glucosidase inhibiting natural products from Macaranga capensis and Sapium integerrimum
This thesis describes the results obtained from the phytochemical studies of Macaranga capensis and Sapium integerrimum as summarized below.
Chemical investigation on the α-glucosidase inhibiting crude methanolic extract of Macaranga capensis resulted in the isolation of two natural products: 3α-hydroxyaleuritolic acid 2-p-hydroxybenzoate (86) and 3-acetoxyoleanolic acid (87) which are related to the class of triterpenoids. Both natural products were isolated for the first time from this plant. The structures of these compounds were elucidated with the aid of NMR spectroscopic data. Both compounds were assayed against α-glucosidase inhibition. Compound (86) exhibited moderate activity in this bioassay with the IC50 value of 2.17mM. Whereas, compound (87) could not be tested as it was only soluble in chloroform and precipitated out in buffer solution. Phytochemical investigation on the ethyl acetate extract of Sapium integerrimum resulted in the isolation of three known compounds; phorbol ester 12-(2’-N-methylaminobenzoyl)-4β,5,20- trideoxyphorbol-13-acetate (113), Quercetin-3-O-α-rhamnopyranoside (114) and scopoletin (115). Compounds 113, 114 and 115 showed good to moderate α-glucosidase inhibitory activity with the IC50 values of 0.57, 0.74 and 1.12 mM, respectively.May 202
Phytochemical studies on Buxus macowanii and microbial transformation of glycyrrhetinic acid
This thesis describes phytochemical studies on Buxus macowanii, a medicinal plant collected from South Africa and the fungal transformation of glycyrrhetinic acid (71), a triterpenoid found in Glycyrrhiza plants.
The crude methanolic extract of B. macowanii was active in the acetylcholinesterase inhibition assay (IC50 = 30 μg/mL). Chemical investigation of its alkaline dichloromethane extract afforded five novel triterpenoidal alkaloids, 31-hydroxybuxatrienone (56), macowanioxazine (57), 16α-hydroxyma-
cowanitriene (58), macowanitriene (59), and macowamine (60), along with two known Buxus bases, Nb-demethylpapillotrienine (61) and moenjodaramine (62). Compounds 56, 57, and 61 exhibited different level of AChE inhibitory activities with compound 56 being significantly active (IC50 = 8.0 μM).
Glycyrrhetinic acid (71) was incubated with Curvularia lunata (ATCC 12017) for ten days to afford one metabolite which was characterized by NMR spectral data as known biotransformed product, 3-oxo-glycyrrhetinic acid (85). This metabolite was previously obtained through biotransformation of 71 by using other fungi.October 201
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