172,115 research outputs found
Biological Activity of Isoflavonoids from Azorella madreporica
No full textQuesada, L (Quesada, Luisa); Astudillo, L (Astudillo, Luis); Gutierrez, M (Gutierrez, Margarita). Univ Talca, Inst Quim Recursos Nat, Talca, Chile .Four isoflavones, isolated from the whole plant of Azurella madreporica, were identified as angustone C (1), alpinumisoflavone (2), licoisoflavone A (3) and isolupalbigenin (4) by spectroscopic studies. The compounds were evaluated for antibacterial and gastroprotective activities. This is the first time that isoflavonoids have been reported in this genus
Corona poética dedicada a la señorita Dª Juana de Villarreal, en la noche de la representación de la zarzuela titulada "El sacristán de San Lorenzo"
No full text2 ej. de la misma obraBHR/C-038-031 (6) Enc. Rúst
An efficient synthesis of new C-2 aryl substituted quinolines based on three component imino Diels-Alder reaction
No full textAstudillo, L. Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla: 747, Talca, Chile.New effective approach to the synthesis of a wide variety of C-2 nitro or aminophenyl substituted quinolines was reported using diverse intermediate 4-(2-oxopyrrolinidyl-1)-tetrahydroquinolines that were prepared by a three component imino Diels-Alder reaction was reported. The key aromatisation process occurs cleanly with the loss of the 2-oxopyrrolinidyl-1 fragment
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Desenvolupament de sintetizadors musicals amb C++ i JUCE
No full text[ES] En este proyecto se expone el desarrollo de dos sintetizadores musicales utilizando el lenguaje de programación C++ y el framework JUCE. Uno de ellos es un sintetizador substractivo el cual se caracteriza por utilizar filtros para modular la forma de onda de osciladores con alto contenido espectral. El otro es un sintetizador FM, que utiliza técnicas de modulación de frecuencia entre osciladores para dar forma a la onda.
Este proyecto profundiza en los distintos algoritmos de procesado de señal necesarios para el diseño de los elementos básicos de un sintetizador musical. En él se presentan algoritmos para la creación de osciladores de banda limitada, filtros, distorsionadores, controles de envolvente y generación de efectos de audio basados en la teoría del procesado digital de señales. Estos algoritmos son implementados en código C++ mediante, dando forma a una aplicación tipo "plug-in" VST/Audio Unit que puede usarse desde cualquier software tipo Digital Audio Workstation (DAW) para interpretar o componer música electrónica.[EN] This project shows the development of two music synthesizers using C++ programming language and JUCE framework. One of them is a substractive synthesizer that filters the waveform of oscillators with high frequency contents using filters. The second one is a FM synthesizer that use Frequency Modulation techniques to shape the sound waves.
This project goes deep into the signal processing algorithms that are necessary for the design of the basic building blocks of a music synthesizer. Algorithms for the design of alias-free oscillators, filters, distortions, envelope controls and audio effects based on theories of Digital Signal Processing. These algorithms are implemented using C++ code. This C++ program forms a VST/Audio unit plug-in application that can be run on any Digital Audio Workstation (DAW) and can be used as a musical instrument to perform or compose electronic music.Calvo Astudillo, J. (2022). Desarrollo de sintetizadores musicales en C++ y JUCE. Universitat Politècnica de València. https://riunet.upv.es/handle/10251/186955TFG
Data and code for Spaulding-Astudillo and Mitchell (2023c), "Clear-sky convergence and the origin of tropical congestus clouds"
No full text<p>Data and code for Spaulding-Astudillo and Mitchell (2023c), "Clear-sky convergence and the origin of tropical congestus clouds".</p><p>The Python code used to create Figures 1, 3-6 and supplementary Figure 1 are included in separate directories. Within each directory, we include experimental data generated by the Reference Forward Model (RFM; Dudhia 2017) that is needed to reproduce the figures. To create the figures, run the provided code in a Jupyter notebook or from the command line. Helper functions for data processing within the figure scripts have the nomenclature ..._data.py. Note that the provided code only allows you to visualize RFM data, not produce it yourself. To do so, you must download and run RFM yourself (https://eodg.atm.ox.ac.uk/RFM/). In addition, Figure 1 requires spatio-temporally averaged data from MERRA-2, ERA5, and CloudSat/CALIPSO (Betrand et al. 2023), which we provide in pickle files. See the main text for data citations, which will allow you to access the original, non-averaged climate data. </p><p>RFM data directories have the nomenclature /ctrl-..... For example, ctrl-RHmid-75-zmid-7-uniform-1 where:<br>RHmid=75% is the relative humidity at a mid-tropospheric height zmid=7.5 km. Uniform=True indicates that the tropospheric relative humidity is constant with height. When uniform=False, the relative humidity follows a C-shaped distribution between the surface and the tropopause. The helper functions in ..._data.py allow you to read the RFM output from .asc files. The nomenclature of the RFM output files is standardized: https://eodg.atm.ox.ac.uk/RFM/. </p><p> </p><p> </p><p> </p><p> </p><p> </p><p> </p><p> </p>
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Biotransformation of Stypotriol triacetate by Aspergillus niger
No full textAstudillo, L (Astudillo, Luis). Univ Talca, Lab Sintesis Organ, Talca, ChileBiological transformation of the meroditerpenoid, stypotriol triacetate (1) by the fungi Aspergillus niger, Cunninghamella elegans, Gibberella fujikuroi and Mucor plumbeus was studied. The incubation of 1 with A. niger yielded the new compound 6',14-diacetoxy-stypol-4,5-dione (2) whose structure was established by (1)H, (13)C and 2D NMR and supported by DFT/GIAO. (C) 2011 Elsevier B.V. All rights reserved
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