592 research outputs found
Some Experiences with Hybrid Genetic Algorithms in Solving the Examination Timetabling Problem
No full textData set contains the instances and software for the algorithms used in the experiments. All experiments can be replicated by use of this software
Replication data and software for: An adaptive large neighbourhood search metaheuristic for hourly learning activity planning in personalised learning
No full textExperimental data and software to replicate the results in Wouda, Aslan and Vis (2022). README files explain the various parts of the data repository
Replication data and software for: An adaptive large neighbourhood search metaheuristic for hourly learning activity planning in personalised learning
No full textExperimental data and software to replicate the results in Wouda, Aslan and Vis (2022). README files explain the various parts of the data repository
Replication data and software for: An adaptive large neighbourhood search metaheuristic for hourly learning activity planning in personalised learning
No full textExperimental data and software to replicate the results in Wouda, Aslan and Vis (2022). README files explain the various parts of the data repository
Which way will Tatar cultur go ? A controversial essay by Galimdzhan Ibragimov
No full textAzade-Ayse Rorlich, Which way will Tatar culture go ? A controversial essay by Galimdzhan Ibragimov.
The present article discusses G. Ibragimov's essay Which way will Tatar culture go ? which demonstrates his awareness of the historical traditions, peculiarities of the Volga Tatars as well as the need to preserve and develop the national identity in the future. Since in his essay Ibragimov posed two alternatives for the future of Tatar culture: russification or survival, the author of this article concentrated around the same issue, comparing Ibragimov's theses with those of other Tatar intellectuals concerned with the future of the Tatar nation. Ibragimov considered the national language as the main ingredient of a national culture and the present article discusses his struggle around this issue as well as his belief that the future of the Tatar culture depended upon the future of the Tatar language.Azade-Ayse Rorlich, Où ira la culture tatare ? Un essai critique de Galimdzhan Ibragimov.
Le présent article discute un essai de G. Ibragimov intitulé Оù ira la culture tatare ? qui démontre la haute conscience qu'avait Ibragimov des traditions historiques et des caractères propres aux Tatars de la Volga, ainsi que la nécessité de préserver et de développer à l'avenir leur identité nationale. Étant donné que, dans son essai, Ibragimov a posé, pour l'avenir de la culture tatare, l'alternative suivante : russification ou survie, la présente étude est centrée sur le même problème et compare les thèses ď Ibragimov à celles des autres intellectuels tatars préoccupés de l'avenir de la nation tatare. Ibragimov considérait la langue nationale comme le principal élément d'une culture nationale ; le présent article remet en cause la bataille qu'il livra à ce sujet et sa conviction que l'avenir de la culture tatare dépendait de celui de la langue tatare.Rorlich Azade-Ayse. Which way will Tatar cultur go ? A controversial essay by Galimdzhan Ibragimov. In: Cahiers du monde russe et soviétique, vol. 15, n°3-4, Juillet-décembre 1974. pp. 363-371
Terrorisme, immigration et patriotisme. Les identités sous surveillance
Get PDFLes attentats du 11 septembre ont eu pour conséquence d’établir une association entre terrorisme et immigration et de mettre en avant la sécurité de la patrie, conduisant à soulever la question de l’allégeance des citoyens d’origine étrangère envers les Etats-Unis. Dans cet article, Ayse Ceyhan analyse les effets des attentats sur l’image et l’identité multiculturaliste des Etats-Unis. Dans cet article, l’auteur souligne que la peur du terrorisme infiltré est devenue la préoccupation sécuritaire majeure. Mais la recherche d’une surveillance accrue des individus et groupes suspects et les mesures adoptées ne sont pas neuve.The attacks of September 11th have consequently established an association between terrorism and immigration and have favoured the idea of national security, which led to questioning the allegiance of citizens from a foreign origin towards the United-States. Ayse Ceyhan analyses the effects of the attacks on the image of the American multicultural identity. The author shows in this article that the fear of an infiltrated terrorism has become the main security preoccupation. Nevertheless, the quest for an increased surveillance of suspect individuals and groups and the measures that have been adopted are not new
Pathway modeling: from gene expression to pathway dynamics
No full textBiological pathways represent a critical level of biological organization and understanding of biochemical pathways is identified as key to future advances in biological sciences (Schaefer, 2004). The overall goal of this thesis is to develop a pathway based approach that integrates different aspects of biological pathways, specifically the structure and the dynamics of a pathway in order to characterize cells’ behavior. Our objectives are to asses structural and functional cross-species comparison of pathways (Chapter 2), to formulate a reliable pathway activity metric based on gene expression data (Chapter 3), to demonstrate that our pathway activity formulation can predict the underlying dynamics (Chapter 4) and finally to demonstrate that the pathway activity formulation can identify cell’s response to a stimulant (Chapter 5). Chapter 3-5 present how a significant pathway can be identified. Then, cross-species comparison of pathways (Chapter 2) can be used. Note that we could have Chapter 2 and Shapter 5 swapped for a more fluent flow. Neverthless, we present the chapters in this order for a better read. In Chapter 2, we propose an improvement of the reaction alignment method, emerged as the most successful pathway comparison method, by accounting for sequence similarity in addition to reaction alignment method. Using nine species, including human and some model organisms and test species, we evaluate the standard and improved comparison methods by analyzing glycolysis and citrate cycle pathways conservation. In addition, we demonstrate how organism comparison can be conducted by accounting for the cumulative information retrieved from nine pathways in central metabolism as well as a more complete study involving 36 pathways common in all nine species. In Chapter 3, we explore an extension of the pathway activity methodology which entails singular value decomposition (SVD) of the expression data of the genes constituting a given pathway. We show that pathway analysis enhances our ability to detect relevant changes in pathway activity using synthetic data. In addition, we illustrate that pathway activity formulation should be coupled with a significance analysis to distinguish significant information from random deviations.In Chapter 4, we perform an unsupervised pathway level analysis, based on the formulation presented in Chapter 3, on a rich time series of transcriptional profiling in rat liver. The over-represented five specific patterns of pathway activity levels, which cannot be explained by random events, exhibit circadian rhythms. The identification of the circadian signatures at the pathway level identify pathways related to energy metabolism, amino acid metabolism, lipid metabolism and DNA replication and protein synthesis, which are biologically relevant in rat liver. In Chapter 5, we demonstrate that our pathway activity formulation enables us to detect relevant changes in pathways due to in utero di-butyl-phthalate (DBP) exposure. Our findings suggest that the pathways that produce precursors to cholesterol synthesis exhibit more significant change compared to the rest of the affected pathways. In addition, pathway activity levels of certain biological functions accompany testosterone decrease, which is the critical event for male reproductive developmental effects of DBP, such as steroid hormone metabolism and biosynthesis of steroids.Ph.D.Includes bibliographical referencesIncludes vitaby Ayse Meric Ovaci
Replication data and software for: An adaptive large neighbourhood search metaheuristic for hourly learning activity planning in personalised learning
No full textExperimental data and software to replicate the results in Wouda, Aslan and Vis (2022). README files explain the various parts of the data repository
Editorial: Compartmental models for social interactions
Get PDF[No Abstract Available]National Recovery and Resilience Plan (NRRP); Mission 4 Component 2 Investment [3277]; European Union [ECS00000033, 1052]The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This research is partially funded under the National Recovery and Resilience Plan (NRRP), and Mission 4 Component 2 Investment 1.5-Call for tender No. 3277 of 30/12/2021 of Italian Ministry of University and Research funded by the European Union-NextGenerationEU Award Number: Project code ECS00000033, Concession Decree No. 1052 of 23/06/2022 adopted by the Italian Ministry.Science Citation Index Expande
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