248 research outputs found
Correction for Khan et al., Global selective sweep of a highly inbred genome of the cattle parasiteNeospora caninum
No full textThe authors note three author names appeared incorrectly. The author name Sarah M. Latham should instead appear as Sophia M. Latham, the author name Elizabeth A. Innes should instead appear as Elisabeth A. Innes, and the author name Johnathan M. Wastling should instead appear as Jonathan M. Wastling. The corrected author line appears below. The online version has been corrected. The authors also note that the author contributions footnote appeared incorrectly. Sophia M. Latham should be credited with designing research, performing research, and contributing new reagents/analytic tools. The corrected author contributions footnote appears below. Asis Khan, Ayako Wendy Fujita, Nadine Randle, Javier Regidor-Cerrillo, Jahangheer S. Shaik, Kui Shen, Andrew J. Oler, Mariam Quinones, Sophia M. Latham, Bartholomew D. Akanmori, Sarah Cleaveland, Elisabeth A. Innes, Una Ryan, Jan Slapeta, Gereon Schares, Luis M. Ortega-Mora, Jitender P. Dubey, Jonathan M. Wastling, and Michael E. Grigg Author contributions: A.W.F., S.M.L., J.P.D., J.M.W., and M.E.G. designed research; A.K., A.W.F., N.R., and S.M.L. performed research; A.K., J.R.-C., J.S.S., K.S., A.J.O., M.Q., S.M.L., B.D.A., S.C., E.A.I., U.R., J.S., G.S., L.M.O.-M., J.P.D., J.M.W., and M.E.G. contributed new reagents/analytic tools; A.K., A.W.F., N.R., and M.E.G. analyzed data; and A.K., J.P.D., J.M.W., and M.E.G. wrote the paper
Facilitating independence: The benefits of a post-diagnostic support project for people with dementia.
No full textProviding support in the form of information, advice and access to services or social events is promoted as beneficial for people newly diagnosed with dementia and their families. This paper reports on key findings from an evaluation of a post-diagnostic support pilot project in Scotland addressing local service gaps, namely information provision, emotional and practical support and maintaining community links. Twenty-seven participants (14 people newly diagnosed with dementia and 13 family carers) were interviewed at two time points: T1 shortly after joining the pilot project and T2 approximately six months later, to ascertain their views on existing services and the support offered by the pilot project. A comparative thematic analysis revealed that the project facilitated increased independence (associated with increased motivation and self-confidence) of people with dementia. The project illustrates what can be achieved if resources are targeted at providing individualised post-diagnostic support, particularly where there are service delivery gaps
Which population level environmental factors are associated with asthma, rhinoconjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One.
No full textThe International Study of Asthma and Allergies in Childhood (ISAAC) Phase One showed large worldwide variations in the prevalence of symptoms of asthma, rhinoconjunctivitis and eczema, up to 10 to 20 fold between countries. Ecological analyses were undertaken with ISAAC Phase One data to explore factors that may have contributed to these variations, and are summarised and reviewed here.In ISAAC Phase One the prevalence of symptoms in the past 12 months of asthma, rhinoconjunctivitis and eczema were estimated from studies in 463,801 children aged 13 - 14 years in 155 centres in 56 countries, and in 257,800 children aged 6-7 years in 91 centres in 38 countries. Ecological analyses were undertaken between symptom prevalence and the following: Gross National Product per capita (GNP), food intake, immunisation rates, tuberculosis notifications, climatic factors, tobacco consumption, pollen, antibiotic sales, paracetamol sales, and outdoor air pollution.Symptom prevalence of all three conditions was positively associated with GNP, trans fatty acids, paracetamol, and women smoking, and inversely associated with food of plant origin, pollen, immunisations, tuberculosis notifications, air pollution, and men smoking. The magnitude of these associations was small, but consistent in direction between conditions. There were mixed associations of climate and antibiotic sales with symptom prevalence.The potential causality of these associations warrant further investigation. Factors which prevent the development of these conditions, or where there is an absence of a positive correlation at a population level may be as important from the policy viewpoint as a focus on the positive risk factors. Interventions based on small associations may have the potential for a large public health benefit
MOLECULAR GEOMETRY AND PREDISSOCIATION TIMES IN THE ELECTRONIC STATE OF HCN AND DCN
No full textG. A. Bickel and K. K. Innes, Can. J. Phys. 62, 1763-1774 (1984). Y. C. Hsu, M. A. Smith, and S. C. Wallace, Chem. Phys. Letters 111, 219-225 (1934).Author Institution: Department of Chemistry, State University of New York at BinghamtonMerging of the vibrational structures of the and electronic states of HCN and DCN into a single , and new measurements of rotational fine structure between 1600 and 1950 {\AA}, have made it possible to attempt refinement of the molecular geometry in the state; an attempt based on rotational constants of HCN, DCN, and will be described. The fine structure is mostly predissociated so that the rotational constants were determined by computer simulation of sub-band contours; in the simulation process it was convenient to measure and analyze also the line-widths of unblended lines in each simulated sub-band. It was then straight forward to estimate -state lifetimes of the DCN’s and their variations with vibrational quantum numbers. These lifetimes range from 120 to 0.4 ps; they will be compared with recently , directly measured lifetimes for lower vibrational levels of the -states of HCN and DCN
How do we get there? Effects of cognitive aging on route memory
No full text© 2017 The Author(s) Research into the effects of cognitive aging on route navigation usually focuses on differences in learning performance. In contrast, we investigated age-related differences in route knowledge after successful route learning. One young and two groups of older adults categorized using different cut-off scores on the Montreal Cognitive Assessment (MoCA), were trained until they could correctly recall short routes. During the test phase, they were asked to recall the sequence in which landmarks were encountered (Landmark Sequence Task), the sequence of turns (Direction Sequence Task), the direction of turn at each landmark (Landmark Direction Task), and to identify the learned routes from a map perspective (Perspective Taking Task). Comparing the young participant group with the older group that scored high on the MoCA, we found effects of typical aging in learning performance and in the Direction Sequence Task. Comparing the two older groups, we found effects of early signs of atypical aging in the Landmark Direction and the Perspective Taking Tasks. We found no differences between groups in the Landmark Sequence Task. Given that participants were able to recall routes after training, these results suggest that typical and early signs of atypical aging result in differential memory deficits for aspects of route knowledge
- …
