4 research outputs found
Implementasi Metode Cepat Kompresi File Document Otomatis Pada Aplikasi Berbasis Web Menggunakan Algoritma Additive Code
No full textOnline data entry systems have largely replaced manual file submission in modern data transmission. Data is often very large. Therefore, a method is needed to reduce the size of the data. File compression, or compression in general, is the name of this method. Compressing files involves transforming multiple document files into a standard encoding format to reduce storage space requirements or increase upload speed. The results of this research inform the use of the Additive Code technique application for file compression, which makes it easier to upload document files automatically and is useful for users. Therefore, the author conducted research with the aim of developing a web-based application. This system can make it easier to upload document files so that it can reduce processing time. Using this method in online applications is useful for creating large document files that can be compressed into smaller ones by following the compression procedure. Data compression test results were obtained by running 10 samples of each document and PDF data file at a speed of less than 3 seconds, with accuracy ranging from 27% to 67% for each sample. We successfully tested ten Word documents and ten PDFs that were uploaded and compressed
Aplikasi Pengolahan Data Permintaan dan Pengeluaran Material Teknik di Perusahaan Umum Daerah Tirta Hidayah Kota Bengkulu Berbasis Web
No full textTirta Hidayah, Bengkulu City, distributes water to customers using pipes and engineering materials designed to work properly. However, this does not always run smoothly, because technical and non-technical problems often occur. To carry out the process of handling and correcting problems that occur in the field, each department must order goods in the warehouse. However, the problem is that the location between offices is quite far and the administration is quite long, making the demand and expenditure of goods not optimal and has an impact on customer service. Of course, this situation can hamper service to customers, because the currently available applications can only be accessed offline. Therefore, the author is interested in creating a web-based application for the PHP programming language and Mysql database. The system development was carried out using the waterfall SDLC model, with the result that the application for processing data on demand and expenditure of engineering materials with a web-based system at the Tirta Hidayah Regional Public Company, Bengkulu City, which was built has been running well, and this application is useful and helps the Service Unit (Processing, Transmission and Distribution Installation, New Installation) and Warehouse Sub Division and Tirta Hidayah General Section of Bengkulu City in the process of requesting and releasing technical materials to be more effective and efficien
Robustness Analysis of QR – Code Based and Geolocation Based Attendance System
No full textThe use of QR-code and GPS technology in the attendance system also has several advantages, such as making the attendance process easier for students, monitoring employee attendance accurately and efficiently, and improving the quality of student work. Therefore, it is important to compare the efficiency of the QR-code attendance method with Geolocation to find out which technology is more effective and efficient in improving the attendance system. In this research the author used the K-means Clustering method. The K-means method is a non-hierarchical data grouping method that attempts to partition existing data into two or more 13 groups. This method partitions data into groups so that data with the same characteristics is included in other groups. The research results show that Cluster 1 has a centeroid that is close to the QR Code features (3,4,4), namely moderate efficiency in application implementation, relatively high ease of use, and system robustness with high data accuracy. Cluster 2 has a centeroid with Geolocation features (3,3,3), namely moderate efficiency and flexibility, moderate ease of use, and system robustness with moderate data accuracy. Thus, after obtaining comparison results between QR code and Geolocation in the lecture attendance process, researchers can recommend the best system to use in terms of user aspects and needs. If the user needs a presence system that prioritizes ease of use and robustness of the system, the user is suited to using the QR-Code system because the usability and durability aspects are relatively high. Meanwhile, if the user prioritizes efficiency and flexibility in the process, it is best to use a presence system in the form of Geolocation, because the results of this research show that the efficient aspect of Geolocation is highe
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
No full textBackground:
Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke.
Methods:
We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515.
Findings:
Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p<0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (<1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (<1%) deaths in the albiglutide group.
Interpretation:
In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes.
Funding:
GlaxoSmithKline
