1,720,954 research outputs found
A skin-interfaced stretchable sensor for solid-phase epidermal biomarkers
No full textSolid-phase epidermal analytes, i.e., cholesterol and lactate, can be used as sensitive biomarkers for diagnosis and monitoring of chronic diseases, such as hyperlipoproteinemia, coronary artery disease, and cardiovascular diseases. However, they are underexplored due to the complicated human skin sample collection process and the use of highly sophisticated instruments like Mass Spectrometry (MS) or High-performance Liquid Chromatography (HPLC) for analysis, which is costly, has a long waiting period, non-continuous, and difficult to miniaturize. To address those daunting challenges, we developed a wearable electronics technology platform that in situ and continuously senses solid-phase epidermal biomarkers, thus eliminating the need for venipuncture, sweat induction or physical exercise, which are necessary for sampling biomarkers in blood or sweat. The key innovation of this novel sensing system is the solvation-diffusion layer, which allows the dissolution of biomarkers into the hydrogel matrix, diffusion of analytes through the matrix, and electrochemical quantification of solid-phase biomolecules at the hydrogel-enzyme interface. The stretchable wearable patch can continuously collect and wirelessly transmit actionable biochemical signals, which is of great importance for remote patient monitoring, digital medicine, and telehealth, and have the potential to partially replace the costly and invasive blood test for screening and monitoring of chronic diseases.Bachelor of Engineering (Materials Engineering
Design, synthesis, and photovoltaic performance of regioisomeric D18-Impact of cross-conjugation on electronic structure and solar cell efficiency
No full textThe unrivaled structural tunability of organic semiconductors allows to tailor their chemical and physical properties for distinct optoelectronic applications. This is particularly true for push-pull conjugated polymers, in which the (hetero)aromatic monomers, substituents, and side chains can be readily adapted. On the other hand, the impact of isomerization within the polymer backbone remains poorly explored. Here, a novel structural isomer of the state-of-the-art push-pull copolymer D18 is synthesized. This 'isoD18' regioisomer shows significantly different optical and electrochemical properties. Its deeper highest occupied molecular orbital energy level and reduced non-radiative voltage losses afford a higher open-circuit voltage (from 0.86 to 0.92 V) for the resulting polymer solar cells. Unfortunately, this is accompanied by a decrease in the short-circuit current density and fill factor, which can mainly be attributed to the one-order-lower hole mobility of isoD18, in line with its reduced thin-film organization. Although the performance of the devices based on the isomeric derivative turns out to be lower in this case, this study does enhance our insights into the effects of regioisomerism in polymer semiconductors on the resulting optoelectronic material and device features.The authors thank Huguette Penxten for the CV analysis and Prof. Anitha Ethirajan for access to the AFM equipment. They also thank the Research Foundation – Flanders (FWO Vlaanderen) for continuing financial support (PhD scholarship 1S98320N (Ka.V.), postdoctoral scholarships 1284623N (T.C.) and 1266923N (S.G.), MALDI‒ToF infrastructure project I006320N, and the Scientific Research Network ‘Supramolecular Chemistry and Materials’ W000620N), as well as the European Research Council (grant agreement 864625). Use of the Stanford Synchrotron Radiation Light source, SLAC National Accelerator Laboratory, is supported by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Contract No. DE-AC02- 76SF00515
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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