1,720,979 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Development of Student Worksheets with Learning Cycle 5E Models on Solubility Product Constant Materials and Their Influence on Student Chemistry Literacy

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    This study aims to develop a student worksheet (LKPD) based on the learning cycle 5E models. The research utilizes the 4D development model by Thiagarajan, which consists of four stages: Define, Design, Develop, and Dissemination. The sample in this study was chemistry teachers and students of SMA Negeri 1 Ngawi. The results of the validation by media and material experts indicate that the LKPD learning cycle 5E is suitable for use in learning. Readability tests conducted by students and teachers show that the LKPD learning cycle 5E falls into the "very good" category. The results of the effectiveness test, using a Mann-Whitney U test, indicate that the LKPD learning cycle 5E has a very small effect on student chemistry literacy in solubility product constant materials.Penelitian ini bertujuan untuk mengembangkan lembar kerja peserta didik (LKPD) berdasarkan model learning cycle 5E. Penelitian ini menggunakan model pengembangan 4D oleh Thiagarajan, yang terdiri dari empat tahap: Define, Design, Develop, dan Dessemination. Sampel dalam penelitian ini adalah guru kimia dan siswa SMA Negeri 1 Ngawi. Hasil validasi oleh ahli media dan materi menunjukkan bahwa LKPD learning cycle 5E cocok untuk digunakan dalam pembelajaran. Uji keterbacaan yang dilakukan oleh siswa dan guru menunjukkan bahwa LKPD learning cycle 5E masuk dalam kategori "sangat baik". Hasil uji efektivitas, menggunakan uji Mann-Whitney U, menunjukkan bahwa LKPD learning cycle 5E memiliki pengaruh yang sangat kecil terhadap literasi kimia siswa dalam materi kelarutan dan hasil kali kelarutan

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    PENGARUH p-HIDROKSI m-METOKSI KALKON (pHmMK) TERHADAP EKSPRESI PROTEIN Bcl-2 dan Bax PADA SEL KANKER PAYUDARA MCF-7

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    Senyawa derivat kalkon yaitu 3-(4’-hidroksi-3’-metoksifenil)-1-fenil-2-propen-1-on) atau para hidroksi meta metoksi kalkon (pHmMK) telah diteliti mampu memacu apoptosis (kematian sel) pada sel kanker payudara MCF-7. Penelitian ini bertujuan untuk mempelajari jalur mekanisme apoptosis senyawa pHmMK pada sel kanker MCF-7 dengan mengamati pengaruhnya terhadap ekspresi protein Bcl-2 dan Bax. Pengamatan ekspresi protein dilakukan dengan metode imunositokimia (ICC) dan dianalisis menggunakan software ImageJ. Hasil penelitian menunjukkan bahwa pemacuan apoptosis oleh pHmMK terjadi melalui mekanisme penurunan ekspresi Bcl-2 dan peningkatan ekspresi Bax</jats:p

    ANTIPLASMODIAL ACTIVITY OF METHANOL EXTRACT HERBAL DRUG PLANTS IN VIVO

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    Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antiplasmodial dari ekstrak metanol tiga jenis spesies tumbuhan, yaitu pegagan, meniran, dan pulai. Metode penelitian yang akan dilakukan adalah dengan melakukan eksperimen di laboratorium, yang di awali dengan pemilihan dan pengumpulan tiga jenis sampel tumbuhan serta dilakukan determinasi di laboratorium Biologi UGM. Selanjutnya dari berbagai jaringan tumbuhan yang biasa digunakan untuk pengobatan, seperti pegagan (semua bagian tumbuhan), meniran (semua bagian tumbuhan), dan pulai (kulit batang), dilakukan ekstraksi secara maserasi dengan pelarut metanol. Ekstrak metanol dari masing-masing spesies tumbuhan dikeringkan dan digunakan untuk uji aktivitas biologi sebagai antiplasmodial secara in vivo. Uji aktivitas antiplasmodial secara in vivo dilakukan dengan cara 4 days suppressive test pada mencit Swiss yang diinfeksi P. berghei. Mencit dibagi menjadi kelompok kontrol (tanpa bahan uji) dan kelompok perlakuan masing-masing menggunakan 5 ekor mencit. Jumlah kelompok perlakuan 5 (lima) sesuai dengan peringkat dosis ekstrak yang digunakan, yaitu 37,25; 62,5;125; 250; dan 500 mg/BB. Hasil penelitian uji aktivitas antiplasmodial secara in vivo ekstrak metanol kulit batang pulai menunjukkan nilai efektivitas dosis (ED50) sebesar 29,78 mg/BB yang termasuk dalam kategori sangat baik, sedangkan aktivitas antiplasmodial dari ekstrak pegagan dan meniran masing-masing dengan ED50 sebesar 970,29 dan 1018,59 mg/BB, sehingga termasuk dalam kelompok tidak aktif. Kata kunci:                  pegagan (Centella asiatica), meniran (Phyllanthus niruri); pulai (Alstonia scholaris), antiplasmodial (antimalaria

    CHARACTERIZATION OF NANOPARTICLES PRODUCED BY CHLOROFORM FRACTION OF KAEMPFERIA ROTUNDA RHIZOME LOADED WITH ALGINIC ACID AND CHITOSAN AND ITS BIOLOGICAL ACTIVITY TEST

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    Objective: The main objectives of this research are to characterize of nanoparticles produced by chloroform fraction of K. rotunda loaded with alginic acid and combination alginic acid-chitosan, and its biological activity test. Methods: Chloroform fraction of K. rotunda was loaded on alginic acid and combination of alginic acid-chitosan nanoparticles by ionic gelation method in various compositions. Characterizations of the products were investigated in particle size, zeta potential, and morphology by Scanning Electron Microscopy (SEM). The biological activity of the products as an antioxidant was tested by the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The cytotoxic effect was analysed using MTT [3-(4,5 dimethyltiazol-2-yl)-2,5-diphenyltetrazoilium bromide] assay.Result:The nanoparticles alginic acid can be synthesized at the optimal mass ratio range of alginic acid : CaCl2 of 10 :1 (% w/v),the percentage nanoparticle products was100%,  the size range of the nanoparticles were 87 to 584 nm, with a zeta potential of -39.0 mV,  and the morphology shows a spherical shape and smooth surface. Furthermore, nanoparticles result from the combination of alginic acid-chitosan at the optimal mass ratio range of alginic acid : chitosan of 10 :1 (% w/v) and added calsium ion at 0.015% w/v, the percentage nanoparticle products was100%, the size range of the nanoparticle were 87 to 877 nm, with a zeta potential of -27.1 mV, and  the morphology shows a form of rectangular beam.Conclusion: The nanoparticle products of chloroform fraction of K. rotunda loaded alginic acid and combination alginic acid-chitosan were successfully obtained  by ionic gelation method. The nanoparticle products show lower activity in antioxidant and cytotoxic effect against human breast cancer T47D cell lines than the starting material chloroform fraction of K. rotunda.Â

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    TECHNOLOGY DEVELOPMENT OF LEATHER PRESERVATION FOR CRAFT HANDICRAFT PRODUCTS

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    The purpose of  this  research   is  developing  preservation   technology  of  the  Pondoh zalacca  and  Zalacca  Gading peel for craft products   material.  The study  begins  with analyzing  content,  water,  carbohydrates, and proteins  in the peel  of zalacca  that is the cause of the growth  of fungus  and microorganisms. The next step is preservation  using borax, formalin, and  chlorine  at concentrations: 2, 4, 6, 8, and  10%. The activity  of fungal   growth  on  the peel  were  observed  in  microscopic,   and  the  characteristics of materials for  craft products  made by observing  the characteristics  of the peel  including the texture, softness,  andfracture. The results showed  that the bark peel has high content of  water which is 74.67% in Pondoh zalacca and 30.06% in zalacca gading. The carbohydrate   content  of  Pondoh  zalacca  peel   at 3.8%,  and  zalacca  gading  peel   at 5.5%. Protein  content at 0.565% in Pondoh zalacca  and 1.815% in zalacca  gading.  The observation for 3 (three) months showed preservation  with borax, formalin,  and chlorine at  all  concentrations  effectively  prevent  fungal   growth.  The  good  peel   elasticity   of Pondoh  zalacca  and  Gading produced by  using borax, formalin, and chlorine  in  the concentration  of below 6%, while giving preservative  chlorine above 4% make the peel a -little whiter, and preservation  of over 4% borax makes chapped peel so it is difficult to be attached to the craft media. Keywords:  Technology, Preservation,  Zalacca peel, and Art Craft

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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