102,326 research outputs found

    Motivation in Extreme Environments: A Case Study of Polar Explorer Pen

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    This study documents the motives of a polar explorer, Pen Hadow, during the period of a 64-day solo expedition in which he skied, without resupply by aircraft, from Canada to the North Geographic Pole. The framework of reversal theory (Apter, 1982) was used to provide a systematic and comprehensive structure for studying such motivation in an extreme environment. Quantitative data were obtained by using the Apter Record of Motivational States. Qualitative data came from interviews structured in terms of reversal theory. The main result was that the explorer needed at different times to call upon all the eight motivational states identified by reversal theory rather than being subject to only the one or two most obvious ones. The telic and autic states were the two that occurred most frequently. Implications for would-be explorers, and for extreme athletes and their coaches, are indicated

    Bi-directional longitudinal associations between different types of bullying victimization, suicide ideation/attempts, and depression among a large sample of European adolescents

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    The SEYLE project is supported by the European Union through the Seventh Framework Program (FP7), Grant agreement number HEALTH-F2-2009-223091.Brunstein Klomek, A., Barzilay, S., Apter, A., Carli, V., Hoven, C.W., Sarchiapone, M., Hadlaczky, G., Balazs, J., Kereszteny, A., Brunner, R., Kaess, M., Bobes, J., Saiz, P.A., Cosman, D., Haring, C., Banzer, R., McMahon, E., Keeley, H., Kahn, J.-P., Postuvan, V., Podlogar, T., Sisask, M., Varnik, A., Wasserman, D

    Long-Range Fluorescence Propagation in Amyloidogenic β-Sheet Films and Fibers

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    Newly developed PEGylated phenylalanine peptide derivatives (PEG-F6) can self-assemble to form hybrid multifunctional nanostructures of homogeneous thin polymer films and amyloid-like fibers. Both adopt a β-sheet architecture and acquire the unique properties of visible fluorescence (FL) found in β-sheet amyloid fibrils also associated with neurodegenerative diseases. A new paradigm observed in PEG-F6 amyloid-like fibers is reported, which demonstrates unique FL and optical absorption (OA) covering the entire visible region. Despite the full overlap of the FL and OA spectra, the FL propagates for an unexpectedly large distance of hundreds of micrometers in these fibers. A new non-waveguiding mechanism of FL light energy transfer in amyloidogenic fibers is proposed based on photon reabsorption theory. The discovered quasi-white FL of PEG-F6 β-sheet amyloidogenic fibers and films consists of the newly observed green FL band along the known blue FL band. The proof-of-concept of long sub-millimeter range FL propagation in specially grown amyloidogenic PEG-F6 fiber-photonic probes is reported. The results indicate that FL can propagate in nanoscale fibers and suggest biomedical applications for FL monitoring of disease-related ultrathin amyloid fibrils and in integrated photonics for optogenetics

    Fold-Sensitive Visible Fluorescence in β-Sheet Peptide Structures

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    Fluorescence (FL) is a basic optical phenomenon that is widely used in molecular spectroscopy, high-resolution microscopy, and bioimaging. It has exciting and emission spectra defined by an electronic structure of particular fluorochrome molecules. In this work, another type of FL is investigated. This FL phenomenon is observed both in biological amyloid and bioinspired amyloidogenic assemblies, folded into specific biomolecular β-sheet secondary structure. A fine mechanism of this fold-sensitive FL effect, arising at the earliest stages of seeding and nucleation of β-sheet nanofibers, and its growth under thermally activated conformational refolding of helical to β-sheet state in bioinspired ultrashort peptide structures are studied. This FL effect demonstrates different properties compared to the classical FL from non-folded biomolecules or molecular dyes. Its excitation and emission spectra are similar in any β-sheet peptide/protein assemblies irrespective of their biochemical composition, primary structure, and origin. It is shown that this fold-sensitive FL effect exhibits a wideband spectrum, covering the entire visible region (400–650 nm), high quantum yield, and tunable FL wavelength. This research paves the way for advanced FL optical nanomaterials, for new methods of bioimaging and diagnostics as well as for the development of biocompatible nanoscale FL sources

    Compulsory admissions of patients with mental disorders: state of the art on ethical and legislative aspects in 40 European countries

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    Wasserman D, Apter G, Baeken C, Bailey S, Balazs J, Bec C, Bienkowski P, Bobes J, Ortiz MFB, Brunn H, Bôke Ö, Camilleri N, Carpiniello B, Chihai J, Chkonia E, Courtet P, Cozman D, David M, Dom G, Esanu A, Falkai P, Flannery W, Gasparyan K, Gerlinger G, Gorwood P, Gudmundsson O, Hanon C, Heinz A, Dos Santos MJH, Hedlund A, Ismayilov F, Ismayilov N, Isometsä ET, Izakova L, Kleinberg A, Kurimay T, Reitan SK, Lecic-Tosevski D, Lehmets A, Lindberg N, Lundblad KA, Lynch G, Maddock C, Malt UF, Martin L, Martynikhin I, Maruta NO, Matthys F, Mazaliauskiene R, Mihajlovic G, Peles AM, Miklavic V, Mohr P, Ferrandis MM, Musalek M, Neznanov N, Ostorharics-Horvath G, Pajević I, Popova A, Pregelj P, Prinsen E, Rados C, Roig A, Kuzman MR, Samochowiec J, Sartorius N, Savenko Y, Skugarevsky O, Slodecki E, Soghoyan A, Stone DS, Taylor-East R, Terauds E, Tsopelas C, Tudose C, Tyano S, Vallon P, Van der Gaag RJ, Varandas P, Vavrusova L, Voloshyn P, Wancata J, Wise J, Zemishlany Z, Öncü F, Vahip

    Bibliographie Hilarion G. Petzold 1958 – 2009 mit Anhang als Einführung

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    Dieses Archiv enthält die Gesamtbibliographie der Werke des Autors nebst einiger Texte „Über H. G. Petzold“ im Schlussteil der Bibliographie sowie einen Anhang mit einer Einführung in die Architektur des Werkes in seinem wissenslogischen Aufbau als Ausarbeitung seines „Tree of Science Modells“ (2007).This archive contains the complete bibliography of the author and some texts about H. G. Petzold, moreover an epilogue with an introduction to the architecture of the works in its epistemological structure and composition and as an elaborations of Petzold’s „Tree of Science Modell (2007).https://www.fpi-publikation.de/polyloge/01-2009-petzold-h-g-gesamtbibliographie-h-g-petzold-1958-2009-updating-november2009/peerReviewedpublishedVersio

    Bullying Victimization and Suicide Ideation and Behavior Among Adolescents in Europe: A 10-Country Study

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    The SEYLE project is supported by the European Union through the Seventh Framework Program (FP7), Grant agreement number HEALTH-F2-2009-223091. Judit Balazs was supported by the Janos Bolyai Research Scholarship of the Hungarian Academy of SciencesBarzilay, S., Brunstein Klomek, A., Apter, A., Carli, V., Wasserman, C., Hadlaczky, G., Hoven, C.W., Sarchiapone, M., Balazs, J., Kereszteny, A., Brunner, R., Kaess, M., Bobes, J., Saiz, P., Cosman, D., Haring, C., Banzer, R., Corcoran, P., Kahn, J.-P., Postuvan, V., Podlogar, T., Sisask, M., Varnik, A., Wasserman, D

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author-springer.pdf

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