4 research outputs found
A Study of Talent Management Practices and Strategies in the Service Sector
No full textTalent management is a mechanism which involves hiring, assigning, transferring, growth and retaining of employees in the organisation. It is important because it ensures top talent is attracted and effective employee performance, employee’s engagement and retainment of top talent. A thorough review of the work carried out shows that businesses are experiencing a talent shortage in this competitive period, which has placed pressure on them to recruit the best talent and to ensure that workers enter the company and choose to remain in the organization rather than seeking opportunities elsewhere. The importance of the different components of talent management for employees was another unexplored area. Existing research has not been able to resolve the problem of defining the importance of the different talent management elements and the weighting they bear for employees. The problem of employee perception and management perception of the efficacy of talent management activities has also not been discussed, to address this gap the researcher has attempted to study talent management practices in service sector. The author followed a systematic approach to address the research questions, the literature was reviewed, in research methodology, primary data was collected through questionnaire which followed a sampling method accompanied by hypothesis testing which revealed that the effective practices boosts up the efficiency of the employees and performance of the organization too
Integrating the management of critical illness with palliative care: Public health implications
No full textCritical illnesses encompass a wide range of serious and life-threatening conditions that often require intensive care, including advanced life support, complex procedures, and prolonged stays in healthcare facilities. Palliative care has been acknowledged as an integral component of critical illness management by complementing curative modes of treatment. The objectives of the current article are to explore the significance of palliative care as an integral domain of the management of critical illnesses, identify the gaps in the integration of palliative care and critical illness, and propose targeted interventions to facilitate this integration. Despite the multiple benefits attributed to palliative care and its role in critical illness management, their integration has not been as expected due to the presence of multiple challenges. The combined delivery of integrated palliative care and critical illness care becomes crucial in improving patient outcomes by improving the management of symptoms
Exploring the Role of Health-care Professionals and Impact of Precision Medicine on Health Outcomes and Efficiency
No full textThe inclusion of precision medicine in medical education represents a paradigm shift, as it is expected to transform the way in which health care will be delivered to patients in future. This shift is predominantly reported as precision medicine strongly advocates for the delivery of personalized care to patients after giving due consideration to the genetic makeup, biomarker level, etc., of the individual patient. Medical professionals are expected to discharge a wide range of roles since the introduction of precision medicine in the health-care industry. Training of medical students and health professionals in the domain of precision medicine is expected to significantly influence patient outcomes and enhance the efficiency of the health-care sector. In conclusion, precision medicine is expected to have a huge impact on medical professionals and the health sector, it is the need of the hour to strengthen its implementation process across medical colleges and health-care facilities
Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice
No full textObjective: The enteroendocrine hormone glucagon-like peptide 1 (GLP-1) is an attractive anti-diabetic therapy. Here, we generated a recombinant Lactococcus lactis strain genetically modified to produce GLP-1 and investigated its ability to improve glucose tolerance in mice on chow or high-fat diet (HFD). Methods: We transformed L. lactis FI5876 with either empty vector (pUK200) or murine GLP-1 expression vector to generate LL-UK200 and LL-GLP1, respectively, and determined their potential to induce insulin secretion by incubating primary islets from wild-type (WT) and GLP-1 receptor knockout (GLP1R-KO) mice with culture supernatant of these strains. In addition, we administered these strains to mice on chow or HFD. At the end of the study period, we measured plasma GLP-1 levels, performed intraperitoneal glucose tolerance and insulin tolerance tests, and determined hepatic expression of the gluconeogenic genes G6pc and Pepck. Results: Insulin release from primary islets of WT but not GLP1R-KO mice was higher following incubation with culture supernatant from LL-GLP1 compared with LL-UK200. In mice on chow, supplementation with LL-GLP1 versus LL-UK200 promoted increased vena porta levels of GLP-1 in both WT and GLP1R-KO mice; however, LL-GLP1 promoted improved glucose tolerance in WT but not in GLP1R-KO mice, indicating a requirement for the GLP-1 receptor. In mice on HFD and thus with impaired glucose tolerance, supplementation with LL-GLP1 versus LL-UK200 promoted a pronounced improvement in glucose tolerance together with increased insulin levels. Supplementation with LL-GLP1 versus LL-UK200 did not affect insulin tolerance but resulted in reduced expression of G6pc in both chow and HFD-fed mice. Conclusions: The L. lactis strain genetically modified to produce GLP-1 is capable of stimulating insulin secretion from islets and improving glucose tolerance in mice. Keywords: Lactococcus lactis, Glucose tolerance, Recombinant bacteria, GLP-
