7,361 research outputs found

    In conversation Dr Denis Burkitt and Sir Anthony Epstein: Addendum

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    Following four interviews with Max Blythe, Dr Denis Burkitt (1911-1993) is joined by former colleague Sir Anthony Epstein to discuss a first meeting in London in 1961 and discussion of a tumour of African children of fascinating geographical distribution. Sir Anthony then takes up the story of the collaborative relationship that ensued in which tumours from Burkitt working in Kampala were despatched to London's Bland Sutton Institute where numerous early attempts to isolate a virus from the tumour tissue failed. Various cell culture techniques were tried but a herpes-like virus was eventually isolated more by luck than judgement. There follows discussion of subsequent research on the implicated virus which proved more widespread and influential than anticipated - the EB virus. Discussion finally turns to progress in the development of a vaccine. It is a fascinating discussion in which the contributors exchange recollections of various lines of collaboration as well as one or two curious administrative barriers to their progress

    Contrasting activity profile of two distributed cortical networks as a function of attentional demands

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    The original publication is available at http://www.jneurosci.orgThis work was supported by R01 grant MH-073610 from the National Institutes of Health to Denis Paré

    Data file for the paper: Jun Wu, Peng Li, Andres Parra-Puerto, Shuang Wu, Xiaoqian Lin, Denis Kramer, Shengli Chen, Anthony Kucernak, "Controllable heteroatom doping effects of CrxCo2-xP Nanoparticles: A Robust Electrocatalyst for Overall Water Splitting in Alkaline Solutions"

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    The data in this spreadsheet was used to produce the figures in the paper Authors:Jun Wu,Peng Li,Andres Parra-Puerto,Shuang Wu,Xiaoqian Lin,Denis Kramer,Shengli Chen,Anthony Kucernak Title:Controllable heteroatom doping effects of CrxCo2-xP Nanoparticles: A Robust Electrocatalyst for Overall Water Splitting in Alkaline Solutions Journal:Acs Applied Materials & Interfaces DOI: 10.1021/acsami.0c10441 Please cite the above reference if you wish to use this data DOI of this data:10.5281/zenodo.406785

    A CONCERT OF WORKS BY Anthony Brandt Denis Gougeon Pierre Jalbert Richard Lavenda Tuesday, November 3, 1998 8:00 p.m. Lillian H. Duncan Recital Hall

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    Presented by SyzygyAudio quality of the recording gradually increases.Program: Dual Velocity / Pierre Jalbert -- Piece de Resistance / Anthony Brandt -- Memory's Motion / Richard Lavenda -- Jeux de Cordes / Denis Gougeo

    Is Tolerance Political? An Interview with Denis Lacorne

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    contribution à un site webDenis Lacorne is the author of "The Limits of Tolerance. Enlightenment Values and Religious Fanaticism" (Columbia University Press, 2019), the English translation of "Les limites de la tolérance" (Gallimard, awarded the Prix Montyon by the Académie Française). In his book, which is intellectually very inspiring because of the many questions it addresses and raises, Denis Lacorne traces the emergence of the notion of tolerance from its early thinkers to the Age of Enlightenment and finally questions the notion and its various understandings through more recent events in France and the United States. What is tolerance? Is tolerance political? Interview by Miriam Périer, CER

    P. Denis, C. Becker (sous la dir. de), The HIV/AIDS epidemic in sub-Saharan Africa in an historical perspective A. Rödlach, Witches, westerners and HIV: AIDS and culture of blame in Africa

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    Billaud Anthony. P. Denis, C. Becker (sous la dir. de), The HIV/AIDS epidemic in sub-Saharan Africa in an historical perspective A. Rödlach, Witches, westerners and HIV: AIDS and culture of blame in Africa . In: Sciences sociales et santé. Volume 25, n°1, 2007. pp. 103-107

    P. Denis, C. Becker (sous la dir. de), The HIV/AIDS epidemic in sub-Saharan Africa in an historical perspective A. Rödlach, Witches, westerners and HIV: AIDS and culture of blame in Africa

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    Billaud Anthony. P. Denis, C. Becker (sous la dir. de), The HIV/AIDS epidemic in sub-Saharan Africa in an historical perspective A. Rödlach, Witches, westerners and HIV: AIDS and culture of blame in Africa . In: Sciences sociales et santé. Volume 25, n°1, 2007. pp. 103-107

    Timing of impulses from the central amygdala and bed nucleus of the stria terminalis to the brainstem

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    The amygdala and bed nucleus of the stria terminalis (BNST) are thought to subserve distinct functions with the former mediating rapid fear responses to discrete sensory cues and the latter longer “anxiety-like” states in response to diffuse environmental contingencies. Yet, these structures are reciprocally connected and their projection sites overlap extensively. To shed light on the significance of BNST-amygdala connections, we compared the antidromic response latencies of BNST and central amygdala (CE) neurons to brainstem stimulation. Whereas the frequency distribution of latencies was unimodal in BNST neurons (~10 ms mode), that of CE neurons was bimodal (~10 and ~30 ms modes). However, after stria terminalis (ST) lesions, only short-latency antidromic responses were observed, suggesting that CE axons with long conduction times course through the ST. Compared to the direct route, the ST greatly lengthens the path of CE axons to the brainstem, an apparently disadvantageous arrangement. Since BNST and CE share major excitatory basolateral amygdala (BL) inputs, lengthening the path of CE axons might allow synchronization of BNST and CE impulses to brainstem when activated by BL. To test this, we applied electrical BL stimuli and compared orthodromic response latencies in CE and BNST neurons. The latency difference between CE and BNST neurons to BL stimuli approximated that seen between the antidromic responses of BNST cells and CE neurons with long-conduction times. These results point to a hitherto unsuspected level of temporal coordination between the inputs and outputs of CE and BNST neurons, supporting the idea of shared functions.The original publication is available at: http://jn.physiology.org/cgi/content/full/100/6/342

    Usability evaluation of the South London and Maudsley NHS Trust Library web site

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    A usability evaluation was carried out of the recently-launched South London and Maudsley NHS Trust library web site using a variety of standard methodologies: content and design evaluation of selected comparable sites, focus groups, a questionnaire survey of library and web development staff, heuristic evaluation, observation testing, card sorting/cluster analysis, and label intuitiveness/category membership testing. All test participants were staff of or providers of services to the trust. Demographic information was recorded for each participant. Unsuccessful attempts were made to evaluate user feedback, and to compare usability test results with usage statistics. Test participants’ overall responses to the site were enthusiastic and favourable, indicating the scope and content of the site to be broadly appropriate to the user group. Numerous suggestions for new content areas were made by testers. Usability problems were discovered in two main areas: in the organisation of the site, and in the terminology used to refer to information services and sources. On the basis of test results, proposals for a revised menu structure, improved accessibility, and changes to the terminology used within the site are presented
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