1,724,862 research outputs found
Improved recognition module for the interpretation of handwritten digits
No full textThesis (S.B. and M.Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1999.Includes bibliographical references (leaves 75-76).by Anshu Sinha.S.B.and M.Eng
Expression of Leukemia/Lymphoma Related Factor (LRF) in Human Breast Carcinoma
No full textThe pox-virus zinc finger protein (POZ-ZF), also termed leukemia/lymphoma related factor (LRF) belongs to the POK family of transcriptional repressors, which is also known as POK erythroid myeloid ontogenic factor (Pokemon), factor binding to short transcripts of HIV-1 (FBI-1), and TTF-1 interacting peptide (TIP21). Its oncogenic role is known only in lymphoma, non-small cell lung carcinoma, and malignant gliomas. The functional expression of LRF in human breast carcinoma has not been confirmed. The aim of this study was to investigate the expression of LRF and propose a mechanism for its function in human breast carcinoma. |The expression of LRF mRNA transcripts and protein in human breast biopsy tissues was quantified by RT-PCR and western blotting. All malignant breast tissues expressed significantly more LRF mRNA transcripts and total protein than the benign breast tissues. LRF expression was also observed in human colon, renal, lung, hepatocellular, mesothelioma, and thymoma carcinomas. In general, a significantly higher expression of LRF was seen in malignant tissue than in the corresponding benign or normal tissue. |LRF expression was high in four of five breast cell lines. Its expression was significantly increased in response to IGF-1, TGF-β1, and TGF-β2 but not EGF. Overexpressed LRF significantly increased TGF-βRII and Smad4 expression. It also activated and interacted with the active p65 subunit of NF-κB. Overexpressed LRF also upregulated the expression of the cyclin A, down- regulated p21CIP/WAF expression and induced cell cycle arrest in the G2 phase. Further studies are warranted to determine the malignant or proliferative role of LRF in human breast carcinoma.xiv, 120 page
Book Review: Anshu Malhotra and Siobhan Lambert-Hurley, eds, Speaking of the Self— Gender, Performance and Autobiography in South Asia
No full text Anshu Malhotra and Siobhan Lambert-Hurley, eds, Speaking of the Self— Gender, Performance and Autobiography in South Asia, Durham and London: Duke University Press, 2015, 312 pp. </jats:p
Synthesis and characterisation of mono- and binuclear palladium and platinum complexes with organochalcogenides
No full textSinghal, Anshu ; Jain, Vimal K. ; Varghese, Babu ; Tiekink, Edward R.T
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Circuit Lower Bounds for Low-Energy States of Quantum Code Hamiltonians
Get PDFThe No Low-energy Trivial States (NLTS) conjecture of Freedman and Hastings [Freedman and Hastings, 2014] - which posits the existence of a local Hamiltonian with a super-constant quantum circuit lower bound on the complexity of all low-energy states - identifies a fundamental obstacle to the resolution of the quantum PCP conjecture. In this work, we provide new techniques, based on entropic and local indistinguishability arguments, that prove circuit lower bounds for all the low-energy states of local Hamiltonians arising from quantum error-correcting codes.
For local Hamiltonians arising from nearly linear-rate or nearly linear-distance LDPC stabilizer codes, we prove super-constant circuit lower bounds for the complexity of all states of energy o(n). Such codes are known to exist and are not necessarily locally-testable, a property previously suspected to be essential for the NLTS conjecture. Curiously, such codes can also be constructed on a two-dimensional lattice, showing that low-depth states cannot accurately approximate the ground-energy even in physically relevant systems
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Separating Quantum Communication and Approximate Rank
Get PDFOne of the best lower bound methods for the quantum communication complexity of a function H (with or without shared entanglement) is the logarithm of the approximate rank of the communication matrix of H. This measure is essentially equivalent to the approximate gamma-2 norm and generalized discrepancy, and subsumes several other lower bounds. All known lower bounds on quantum communication complexity in the general unbounded-round model can be shown via the logarithm of approximate rank, and it was an open problem to give any separation at all between quantum communication complexity and the logarithm of the approximate rank.
In this work we provide the first such separation: We exhibit a total function H with quantum communication complexity almost quadratically larger than the logarithm of its approximate rank. We construct H using the communication lookup function framework of Anshu et al. (FOCS 2016) based on the cheat sheet framework of Aaronson et al. (STOC 2016). From a starting function F, this framework defines a new function H=F_G. Our main technical result is a lower bound on the quantum communication complexity of F_G in terms of the discrepancy of F, which we do via quantum information theoretic arguments. We show the upper bound on the approximate rank of F_G by relating it to the Boolean circuit size of the starting function F
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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