1,720,960 research outputs found

    Liposomes as biomimetic microreactors

    No full text
    Liposomes have become an important model in fundamental biomembrane research, including biophysical, biochemical, and cell biological studies of membranes and cell function. They are thoroughly studied in several applications, such as drug delivery systems in medical applications and as controlled release systems, microencapsulating media, signal carriers, support matrices, and solubilizers in other applications. While medical applications have been extensively reviewed in recent literature, there is a need for easily accessible information on applications for liposomes beyond pharmacology and medicine. The Handbook of Nonmedical Applications of Liposomes fills this void. This unique new handbook series presents recent developments in the use of liposomes in many scientific disciplines, from studies on the origin of life, protein function, and vesicle shapes, to applications in cosmetics, diagnostics, ecology, bioreclamation, and the food industry. In these volumes many of the top experts contribute extensive reviews of their work

    Liposomes as bioreactors. Transport/kinetic phenomena

    No full text
    This study concerns the biochemical and physicochemical behaviour of liposomes as enzymatic bioreactors. The aim is to study a quantitative treatment of transport/kinetic phenomena in these bioreactors. The experimental system studied is the enzyme ascorbate oxidase (AAO) entrapped into dipalmitoyl-phosphatidylcholine unilamellar vesicles. The vesicles were prepared by two different methods, namely by controlled detergent dialysis technique or by reverse phase technique. A kinetic model which considers the presence of AAO both on the surface and in the aqueous core of the liposomes has been developed

    Fattori limitanti nella elettrogenerazione catodica di radicali ossidrile

    No full text
    Sono presi in esame i fattori limitanti nel processo di produzione di acqua ossigenata per riduzione catodica dell’ossigeno nel caso dell’elettrodo di grafite e dell’elettrodo composito di grafite a diffusione di gas e viene proposto un modello che rappresenti i due sistemi in esame. Quest’ultimo viene utilizzato per verificare l’effetto delle variabili di processo sulle prestazioni del sistema ovvero la produzione specifica netta di acqua ossigenata con un determinato rendimento di corrente. Il modello stesso potrà consentire di valutare anche le condizioni ottimali per la produzione del radicale ossidrile, verificando anche il processo di rigenerazione per riduzione degli ioni ferrosi ossidati a ioni ferrici nel corso della reazione di Fenton

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Full text link
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

    Full text link
    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

    Full text link
    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
    corecore