660 research outputs found
Hackett tree
No full textPhylogeny of the species present in the included studies, following the 'Hackett tree' (see Jetz et al. 2012; birdtree.org
Student Teaching Internship, Monsignor John R. Hackett High School
No full text6 p.The author describes her experience as a high school student teacher.Monsignor John R. Hackett High School. Kalamazoo, Michigan
14th annual John Perkins Lecture
No full textDr. John Perkins returns to campus Tuesday, April 30, 11 a.m., at First Free Methodist Church, for the 14th annual John Perkins Lecture Series. This year’s morning event features Erna Kim Hackett, executive pastor at The Way Berkeley. Later that day, Hackett and Dr. Perkins will continue the morning’s topic, “Words Have Power,” at 7:30 p.m., also in First Free Methodist Church.
John Perkins is one of the leading evangelical voices to come out of the American civil rights movement and an internationally known author, speaker, and teacher. His is the co-founder of SPU’s John Perkins Center for Reconciliation, Leadership Training, and Community Development and the author of the new book One Blood: Parting Words to the Church on Race and Love. Erna Kim Hackett served with InterVarsity for 18 years in Black Ministries and Urban Programs. She is a preacher, pastor, writer, activist, and singer
2007 - biennial review - 2009
No full textReporting period: July 1, 2007-June 30, 2009.Assembled and reviewed by: Reagan Waskom, Nancy Grice, Zach Hittle, Kevin Hackett
Future winds : A review of the likely impacts of anthropogenic climate change on wind engineering in the UK
No full textCorrigendum to “Accumulation and potential for transport of microplastics in stormwater drains into marine environments, Perth region, Western Australia” [Mar. Pollut. Bull. 168 (2021) 112362]
No full textThe authors regret that the original manuscript failed to appropriately acknowledge all sources of intellectual and technical contribution, which warrant co-authorship. Dr Mark J Hackett (School of Molecular and Life Sciences, Curtin University, Bentley 6102 WA, Australia) is now recognised as a co-author of this manuscript with respect to intellectual input into the design of ATR-FTIR experiments and interpretation of the ATR-FTIR spectra. Dr Hackett is also recognised as the sole co-author responsible for training the first author of this paper in the use of ATR-FTIR research equipment. The ATR-FTIR equipment used for this study is housed within the School of Molecular and Life Sciences at Curtin University, and all authors gratefully acknowledge Curtin University for providing access to this equipment. The authors would like to apologise for any inconvenience caused. Natasha Lutz: Conceptualization, Methodology, Software, Data curation, Investigation, Formal analysis, Visualization, Writing – original draft, Writing – review & editing. James Fogarty: Data curation, Formal analysis, Methodology, Writing – review & editing, Supervision. Andrew Rate: Conceptualization, Methodology, Writing – review & editing, Supervision. Mark J. Hackett: Investigation, Data curation, Visualization
Harag György: Anna Frank naplója, 1958
No full textTanulmányomban Harag György Anna Frank naplója című 1958-as előadását rekonstruálom, melyet Harag az induló, fiatal nagybányai társulat vezetőjeként rendezett. A philter módszer alapján, hat főbb szempontot vizsgálva elemzem az előadást.
Az Anna Frank naplójával a fiatal szatmári társulat elnyerte a legjobb előadásért és a legjobb női alakításért járó díjat Bukarestben, az Országos Színházi Fesztiválon 1958-ban, ezzel elérve a kívánt szakmai áttörést. Államszocializmus éveiben az Anna Frank naplóján kívül nem mutatnak be Romániában a shoat bemutató vagy feldolgozó művet. A Goodrich-Hackett szerzőpár által dramatizált és Broadwayn nagy sikerrel játszott darabot, rengeteg országban bemutatják, figyelmen kívül hagyva a napló szövegének átalakítása nyomán megformálódó hamis Anna Frank képet, illetve a holokausztot elbagatellizáló irányt. Harag György a plakáton “igaz történetként” jelöli meg a művet, Kötő József dokumentumdrámaként hivatkozik rá. Hat évtizeddel a bemutató után ezt újra kell értékelnünk.
A fényképes és videó-dokumentáció hiányából fakadóan mind a színészi játékot, mind az előadás látványvilágát az írott sajtó, visszaemlékezések, szövegkönyv és a néhány fennmaradt fénykép alapján végeztem el, arra a következtetésre jutva, hogy a színészi játék egységes, Harag György módszerét követő az építkezés, míg a látvány valószínűleg megegyezik, az akkori általánosan használt Anna Frank naplója színpadképpel
MCL-1 localizes to sites of DNA damage and regulates DNA damage response
No full textMCL-1, a pro-survival member of the BCL-2 family, was previously shown to have functions in ATR-dependent Chk1 phosphorylation following DNA damage. To further delineate these functions, we explored possible differences in DNA damage response caused by lack of MCL-1 in mouse embryo fibroblasts (MEFs). As expected, Mcl-1(-/-) MEFs had delayed Chk1 phosphorylation following etoposide treatment, compared to wild type MEFs. However, their response to hydroxyurea, which causes a G(1)/S checkpoint response, was not significantly different. In addition, appearance of gamma-H2AX was delayed in the Mcl-1(-/-) MEFs treated with etoposide. We next investigated whether MCL-1 is present, together with other DNA damage response proteins, at the sites of DNA damage. Immunoprecipitation of etoposide-treated extracts with anti-MCL-1 antibody showed association of MCL-1 with gamma-H2AX as well as NBS1. Immunofluorescent staining for MCL-1 further showed increased co-staining of MCL-1 and NBS1 following DNA damage. By using a system that creates DNA double strand breaks at specific sites in the genome, we demonstrated that MCL-1 is recruited directly adjacent to the sites of damage. Finally, in a direct demonstration of the importance of MCL-1 in allowing proper repair of DNA damage, we found that treatment for two brief exposures to etoposide , followed by periods of recovery, which mimics the clinical situation of etoposide use, resulted in greater accumulation of chromosomal abnormalities in the MEFs that lacked MCL-1. Together, these data indicate an important role for MCL-1 in coordinating DNA damage mediated checkpoint response, and have broad implications for the importance of MCL-1 in maintenance of genome integrity.Peer reviewedfinal article publishedprotein complexchromosomesG2/McheckpointDNA repai
Facet Theory and the Mapping Sentence: Evolving Philosophy, Use and Application
No full textHow do we think about the worlds we live in? The formation of categories of events and objects seems to be a fundamental orientation procedure. Facet theory and its main tool, the mapping sentence, deal with categories of behavior and experience, their interrelationship, and their unification as our worldviews. In this book Hackett reviews philosophical writing along with neuroscientific research and information form other disciplines to provide a context for facet theory and the qualitative developments in this approach. With a variety of examples, the author proposes mapping sentences as a new way of understanding and defining complex behavior
Is there a Mendelian transmission ratio distortion of the c.429_452dup(24bp) polyalanine tract ARX mutation?
No full textAdvance online publication 11 April 2012Intellectual disability is common. Aristaless-related homeobox (ARX) gene is one of the most frequently mutated and pleiotropic genes, implicated in 10 different phenotypes. More than half of ~100 reported cases with ARX mutations are due to a recurrent duplication of 24 bp, c.429_452dup, which leads to polyalanine tract expansion. The excess of affected males among the offspring of the obligate carrier females raised the possibility of transmission ratio distortion for the c.429_452dup mutation. We found a significant deviation from the expected Mendelian 1:1 ratio of transmission in favour of the c.429_452dup ARX mutation. We hypothesise that the preferential transmission of the c.429_452dup mutation may be due to asymmetry of meiosis in the oocyte. Our findings may have implications for genetic counselling of families segregating the c.429_452dup mutation and allude to putative role of ARX in oocyte biology.Cheryl Shoubridge, Alison Gardner, Charles E. Schwartz, Anna Hackett, Michael Field and Jozef Gec
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