1,720,961 research outputs found
Hypoglycemic Effect of Combination of Azadirachta indica A. Juss. and Gynura procumbens (Lour.) Merr. Ethanolic Extracts Standardized by Rutin and Quercetin in Alloxan-induced Hyperglycemic Rats
Get PDFPurpose: Exploration of plant combinations could be an alternative approach for diabetes treatment. The aim of this study is to evaluate the hypoglycemic effect of combination of A. indica and G. procumbens ethanolic extract s in alloxan - induce d diabetic rats. Metho ds : Powder of A. indica and G. procumbens leaves were macerated with ethanol 70%. Determination of rutin in A. indica and quercetin in G. procumbens w ere performed by TLC - densitometry. Hyperglycemia in rats was induced by an intraperitoneal injection of alloxan monohydrate at a single dose of 150 mg/kgBW. The rats were treated with 3 dosage variation of combinations for 15 days. Hypoglycemic effect was evaluated by estimating the blood glucose levels and the rats pancreas histological study . Results: A. i ndica contained 2. 90 ±0.15% of rutin and G. procumbens contained 18.86±0.86% of quercetin. Combination at the ratio of 50mg/kgBW A. indica : 112.5mg/kgBW G. procumbens showed the highest hypoglycemic effect: 68 . 74±4 . 83% (preprandial) and 73 . 9 1 ±3 . 18% (postprandial). Histolog ical studies indicated that this combination improved the mor ph ology of the islets of Langerhans and β cells. It also increased insulin expression and decreased the elevated - glucose concentrations . Conclusion: This study showed that combination of both extracts has better hypoglycemic effect than the single treatment of A. indica or G. procumbens . Combination of both extracts was potential to develo p as a blood glucose - lowering agent for diabetic patients
Aktivitas Antibakteri Ekstrak Sargassum polycystum dari Pantai Batu Layar, Nusa Tenggara Barat
No full textSargassum polycystum termasuk dalam kelas Phaeophyceae atau rumput laut coklat yang memiliki metabolit sekunder yang bermanfaat bagi kesehatan, termasuk antibakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak etanol 96% S. polycystum dan fraksinya terhadap Staphylococcus aureus ATCC 25923. Sejumlah sampel S. polycystum dikumpulkan dari Pantai Batu Layar, Lombok Barat, Provinsi Nusa Tenggara Barat. Sampel diekstraksi dengan metode maserasi (3x24 jam) dan difraksinasi menggunakan corong pisah, sehingga diperoleh ekstrak etanol pekat S. polycystum dan fraksi n-heksana, fraksi etil asetat dan fraksi air. Selanjutnya dilakukan uji skrining fitokimia untuk mengetahui kandungan alkaloid, flavonoid, saponin, tanin dan steroid/terpenoid. Hasil pemeriksaan metabolit sekunder pada ekstrak etanol mengandung semua metabolit sekunder kecuali triterpenoid, fraksi n-heksana hanya mengandung alkaloid dan steroid, fraksi etil asetat mengandung saponin dan steroid dan fraksi air mengandung flavonoid dan tanin. Uji aktivitas antibakteri ekstrak dan ketiga fraksi dilakukan dengan metode difusi cakram. Perlakuan terdiri dari ekstrak etanol 96%, fraksi n-heksana, fraksi etil asetat dan fraksi air S. polycystum dengan konsentrasi masing-masing 25% b/v, 50% b/v 80% b/v dan 100% b/v. Kontrol positif yang digunakan adalah kloramfenikol 0,1%. Analisis data menggunakan uji One Way ANOVA dengan program SPSS. Hasil penelitian menunjukkan bahwa ekstrak etanol bersama fraksi rumput laut coklat S. polycystum memiliki aktivitas antibakteri terhadap S. aureus ATCC 25923 (p<0,05)
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Growth and yield of rice plants frown in media containing several formulations of brown algae organic fertilizer
No full textDispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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