17,495 research outputs found
Marriage record of Lopez, Alejandro and Valdes, Rosario
No full textMarriage license for Alejandro Lopez and Rosario Valdes. Joseph A. Lopez was the Notary Public
Author response
Get PDFDetecting pathogens and mounting immune responses upon infection is crucial for animal health. However, these responses come at a high metabolic price (McKean and Lazzaro, 2011, Kominsky et al., 2010), and avoiding pathogens before infection may be advantageous. The bacterial endotoxins lipopolysaccharides (LPS) are important immune system infection cues (Abbas et al., 2014), but it remains unknown whether animals possess sensory mechanisms to detect them prior to infection. Here we show that Drosophila melanogaster display strong aversive responses to LPS and that gustatory neurons expressing Gr66a bitter receptors mediate avoidance of LPS in feeding and egg laying assays. We found the expression of the chemosensory cation channel dTRPA1 in these cells to be necessary and sufficient for LPS avoidance. Furthermore, LPS stimulates Drosophila neurons in a TRPA1-dependent manner and activates exogenous dTRPA1 channels in human cells. Our findings demonstrate that flies detect bacterial endotoxins via a gustatory pathway through TRPA1 activation as conserved molecular mechanism.sponsorship: Vlaams Instituut voor Biotechnologie Alessia Soldano Luis Franco Guangda Liu Natalia Mora Emre Yaksi Bassem A Hassanr Fonds Wetenschappelijk Onderzoek G.0702.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0077.15 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0680.10 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0681.10 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0503.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0654.15 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0761.10N Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0596.12 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar Fonds Wetenschappelijk Onderzoek G.0565.07 Alessia Soldano Yeranddy A Alpizar Brett Boonen Alejandro Lopez-Requena Natalia Mora Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar KU Leuven GOA/14/011 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar European Commission IUAP P7/13 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekensr KU Leuven OT/12/091 Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talaverar KU Leuven PF-TRPLe Alessia Soldano Yeranddy A Alpizar Brett Boonen Luis Franco Alejandro Lopez-Requena Guangda Liu Natalia Mora Emre Yaksi Thomas Voets Rudi Vennekens Bassem A Hassan Karel Talavera (Vlaams Instituut voor Biotechnologie, Fonds Wetenschappelijk Onderzoek|G.0702.12, Fonds Wetenschappelijk Onderzoek|G.0077.15, Fonds Wetenschappelijk Onderzoek|G.0680.10, Fonds Wetenschappelijk Onderzoek|G.0681.10, Fonds Wetenschappelijk Onderzoek|G.0503.12, Fonds Wetenschappelijk Onderzoek|G.0654.15, Fonds Wetenschappelijk Onderzoek|G.0761.10N, Fonds Wetenschappelijk Onderzoek|G.0596.12, KU Leuven|GOA/14/011, KU Leuven|OT/12/091, European Commission|IUAP P7/13, KU Leuven PF-TRPLe)status: Publishe
Architectural atmosphere and the man-place relationship: the case study of the Dominguez House (1970-1980)
No full textIf architecture reads dwelling as being simultaneously located in space and exposed to a certain environmental character, places have to be analysed by means of the categories space and character. While space denotes the three-dimensional organization of the elements which make up a place, character signifies the general atmosphere which is the most comprehensive property of any place. A phenomenology of architecture comprises not just a survey of manifest atmospheres but also an investigation of their concrete determinants.
Atmosphere is made manifest through the detail: similar spatial configurations can have very different characters according to the concrete solution of their boundaries. How a boundary is depends upon its formal articulation, which is again related to the way it is “built”. The outside-inside relation that the boundary establishes offers thresholds, transitions between the inside and the outside, a feeling of being sheltered and, ultimately, a total man-place relationship, a feeling of being in place.
Spanish architect Alejandro De la Sota developed a contemporary understanding of dwelling through the challenging design and construction of the Dominguez House between 1970 and 1980. This domestic project investigates the boundary as a key element in the relationship between man and place: man positions himself in place according to his own awareness of being through time. Through the case study of the Dominguez House (Spain), the paper examines the unfolding of an architectural exploration of the concept of dwelling. The work concludes presenting atmosphere as a key element for architecture to offer man a feeling of belonging
Interview with Alejandro López
No full textAlejandro López talks about the electronic music scene and Tijuana and the music that young people are making more generally.https://scholarworks.utrgv.edu/alejandromadrid/1000/thumbnail.jp
Del fordismo a la revolución actual del proceso de trabajo y de sus respectivas condiciones generales de la reproducción /
No full text\ua0tesis que para obtener el grado de Doctorado en Economía, presenta Miguel Angel Lara Sánchez ; asesor Alejandro Rogelio Álvarez Béjar332 páginas :\ua0ilustracionesDoctorado en Economía\ua0UNAM, Facultad de Economía,\ua0201
Evaluación y caracterización de los efectos citotoxico y antitumoral de kaempferitrina /
No full text\ua0tesis que para obtener el grado de Doctorado en Ciencias Bioquímicas, presenta Angel Josabad Alonso Castro ; asesor Alejandro Garcia Carranca70 páginas :\ua0ilustracionesDoctorado en Ciencias Bioquímicas\ua0UNAM, Facultad de Química,\ua0201
The physiology of Clostridium thermocellum : the toxicity of its fermentation products in relation to the energy metabolism
No full textThesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Nutrition and Food Science, 1981.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Vita.Bibliography: leaves 332-370.by Alejandro Angel Herrero-Molina.Ph.D
Oral history interview with Aaron Alejandro, 1997
Get PDFThe interview opens with a discussion of Alejandro\u27s family history and turns to his youthful misbehavior, which resulted in his being sent to Cal Farley\u27s Boys Ranch. Alejandro goes into detail about his experiences at Boys Ranch and the effect upon his life of his time there. He talks at length about his involvement in Future Farmers of America and his campaign for and year as its state president, during which he toured Texas keeping speaking engagements and promoting FFA. Nearing graduation from Texas Tech University, Alejandro accepted employment as district coordinator for U.S. Representative Bill Sarpalius. He discusses his work for the congressman and gives his opinions as to why Sarpalius lost his seat in 1994. Alejandro talks about racism in the Texas Panhandle and in Montague, Wise and Wichita counties, his unsuccessful campaign for the 13th District U.S. House seat, and the campaign for Wichita County judge in which he was engaged at the time of the interview
Influencias de las redes de transportes en la historia de los asentamientos humanos en la Argentina
No full textFil: García Rodríguez, Angel. Universidad de Buenos Aires. Facultad de Ciencias Económicas. Buenos Aires, Argentina.Fil: Rofman, Alejandro B.. Universidad de Buenos Aires. Facultad de Ciencias Económicas. Buenos Aires, Argentina
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