146,330 research outputs found
Ensayo y memoria, trabajos académicos: Actividades y sugerencias de Eugenio Núñez ang
No full textReseña del libro Eugenio Núñez Ang, Ensayo y memoria. Trabajos académicos: actividades y sugerencias, Toluca, UAEM, 2009
Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy
No full textMaternal endothelial dysfunction in preeclampsia is associated with increased soluble fms-like tyrosine kinase-1 (sFlt-1), a circulating antagonist of vascular endothelial growth factor and placental growth factor. Angiotensin II (Ang II) is a potent vasoconstrictor that increases concomitant with sFlt-1 during pregnancy. Therefore, we speculated that Ang II may promote the expression of sFlt-1 in pregnancy. Here we report that infusion of Ang II significantly increases circulating levels of sFlt-1 in pregnant mice, thereby demonstrating that Ang II is a regulator of sFlt-1 secretion in vivo. Furthermore, Ang II stimulated sFlt-1 production in a dose- and time-dependent manner from human villous explants and cultured trophoblasts but not from endothelial cells, suggesting that trophoblasts are the primary source of sFlt-1 during pregnancy. As expected, Ang II-induced sFlt-1 secretion resulted in the inhibition of endothelial cell migration and in vitro tube formation. In vitro and in vivo studies with losartan, small interfering RNA specific for calcineurin and FK506 demonstrated that Ang II-mediated sFlt-1 release was via Ang II type 1 receptor activation and calcineurin signaling, respectively. These findings reveal a previously unrecognized regulatory role for Ang II on sFlt-1 expression in murine and human pregnancy and suggest that elevated sFlt-1 levels in preeclampsia may be caused by a dysregulation of the local renin/angiotensin system
Ang Ikatlong Dekada: Ang Sitwasyon at Mungkahing Pagpapaunlad ng Panitikang Pambata sa Pilipinas (2000-2009)
No full text Nakatutok itong pag-aaral sa kalagayan ng panitikang pambata sa Pilipinas mula 2000 hanggang 2009. Tinatalakay ng preliminaryong pagsisiyasat ang mga sumusunod na usapin at tunguhin sa mga sumusunod na aspekto ng produksiyon ng nasabing anyo: mga kapangahasan sa panitikang pambata; paglalathala sa mga radikal na tekstong pambata; panitikang pambatang nilikha ng mga bata; aklat pambata mula sa rehiyon; mga aklatang pambata, kasama na ang mga online library; kritisismo at pananaliksik; mga gawad at timpalak pampanitikan; mga organisasyon; at ang tungkulin ng muling pagsasalaysay (retelling) ng mga klasiko at panitikang-bayan. Rekomendasyon ang huling bahagi ng pananaliksik tungo sa pagpapaunlad ng panitikang pambata sa bansa. Naglaan din ng detalyadong timeline ang mananaliksik na magsisilbing tulong at gabay sa mga iskolar at mananaliksik. The paper focuses on the situation of children’s literature in the Philippines from 2000 to 2009. This preliminary study discusses the following issues and trends in the aspects of production: sensitive topics in children’s books; publishing radical texts; children’s literature written by children; children’s literature from the regions; children’s libraries and online libraries; criticism and research; awards and literary contests; organizations; and the role of retelling of classic literature and folklore. The last part of the study is a recommendation towards the development of the literary form. A detailed timeline is also provided as an aid and guide to future scholars and researchers. Keywords: children’s literature, trends, issues, children’s books 
Ang persepsyon ng mga babaeng biktima ng incest sa kanilang salarin at ang kasalukuyang pakikisalamuha nila sa kalalakihan
No full textAng deskriptibong pag-aaral na ito ay isinagawa upang malaman ang persepsyon ng mga babaeng biktima ng incest sa kanilang salarin bago at matapos ang akto ng incest, ang ang kasalukuyang pakikisalamuha ng mga ito sa kalalakihan. Nakuha ang limang (5) kalahok sa pamamagitan ng referral at ang paraan ay non-probability purposive sampling. Ang mga kalahok ay pawang mga kababaihan na may edad 10-20 taong gulang at ang kanilang karanasan ng incest ay nangyari sa pagitan ng childhood at adolescent na yugto ng kanilang buhay. Ang mga kalahok ay dumaan sa malalimang pakikipanayam bilang metodo ng pagkalap ng datos na ginamitan ng semi-structured na gabay para sa instrumento. Bunga ng masusing pagsusuri ng mga datos na nakuha, napag-alaman na mayroong naging pagkakaiba sa persepsyon ng mga biktima sa kanilang salarin bago at matapos mangyari ang incest sa kanilang buhay. Ang pagkakaibang ito ay makikita sa pamamagitan ng pagkakaroon ng positibong persepsyon ang biktima sa kanyang salarin bago mangyari ang incest na naging negatibong persepsyon matapos mangyari ang incest. Maging ang kanilang pakikisalamuha sa kamag-anak na lalake at ibang kalalakihan ay nagkaroon ng pagkakaiba habang ang kanilang pakikisalamuha sa mga kaibigang lalake ay nanatiling halos magkatulad, bago at matapos mangyari ang incest
Ensayo y memoria, trabajos académicos: Actividades y sugerencias de Eugenio Núñez ang
No full textReseña del libro Eugenio Núñez Ang, Ensayo y memoria. Trabajos académicos: actividades y sugerencias, Toluca, UAEM, 2009
Ensayo y memoria. Trabajos académicos: actividades y sugerencias de Eugenio Núñez Ang
No full textReseña del libro Eugenio Núñez Ang, Ensayo y memoria. Trabajos académicos: actividades y sugerencias, Toluca, UAEM, 2009
Long-run pass-through from the exchange rate to import prices in African countries
No full textThis paper investigates the extent of pass-through from the nominal exchange rate to import prices for a sample of nineteen African countries. The methodology is based on panel data cointegration testing. Using annual data extending back to 1971, long-run pass-through can be best described as a fairly balanced combination of local-currency and producer-currency pricing. However, this paper offers additional insight from a moving window approach that indicates declining long-run pass-through, accompanied by decreasing inflation, occurring since the mid-1990s
PID control system analysis, design, and technology
No full textDesigning and tuning a proportional-integral-derivative
(PID) controller appears to be conceptually intuitive, but can
be hard in practice, if multiple (and often conflicting) objectives
such as short transient and high stability are to be achieved.
Usually, initial designs obtained by all means need to be adjusted
repeatedly through computer simulations until the closed-loop
system performs or compromises as desired. This stimulates
the development of "intelligent" tools that can assist engineers
to achieve the best overall PID control for the entire operating
envelope. This development has further led to the incorporation
of some advanced tuning algorithms into PID hardware modules.
Corresponding to these developments, this paper presents a
modern overview of functionalities and tuning methods in patents,
software packages and commercial hardware modules. It is seen
that many PID variants have been developed in order to improve
transient performance, but standardising and modularising PID
control are desired, although challenging. The inclusion of system
identification and "intelligent" techniques in software based PID
systems helps automate the entire design and tuning process to
a useful degree. This should also assist future development of
"plug-and-play" PID controllers that are widely applicable and
can be set up easily and operate optimally for enhanced productivity,
improved quality and reduced maintenance requirements
Comparison of team effectiveness between globally distributed and locally distributed engineering project teams
No full text- …
