2,035 research outputs found
The concept of a system of comfortable public spaces in the city of Kursk
No full textThe article deals with the problem of the improvement of public spaces in large cities on the example of Kursk. The author suggests using the existing infrastructure of the city to create a comfortable environment and increase its recreational opportunities for local residents and tourists. The study is aimed at creating a system of comfortable public spaces using the ecological, historical and cultural resources of the city, where the parks and squares of Kursk play a key role. The practical use of this concept contributes to the improvement of the city’s image and the development of a comfortable urban environment
Search for the Higgs Boson Decays to a Photon and Two Leptons with Low Dilepton Invariant Mass.
No full textA search for a Higgs boson decay is presented. The analysis is performed using proton-proton collision data recorded by the CMS detector at the CERN LHC at a centre-of-mass energy of 8 TeV, corresponding to an integrated luminosity of 19.7 fb. The selected events have an opposite-sign muon or electron pair and a high transverse momentum photon. No excess above background has been found in the three-body invariant mass range GeV, and limits have been derived for the Higgs boson production cross section times branching fraction for the decay, where the dilepton invariant mass is less than 20 GeV. For a Higgs boson with GeV, a confidence level (CL) exclusion observed (expected) limit is 6.7 () times the standard model prediction. Additionally, a search for process is presented, and an upper limit at CL on the branching fraction of the decay for the 125 GeV Higgs boson is set at .A search for a Higgs boson decay is presented. The analysis is performed using proton-proton collision data recorded by the CMS detector at the CERN LHC at a centre-of-mass energy of 8 TeV, corresponding to an integrated luminosity of 19.7 fb. The selected events have an opposite-sign muon or electron pair and a high transverse momentum photon. No excess above background has been found in the three-body invariant mass range GeV, and limits have been derived for the Higgs boson production cross section times branching fraction for the decay, where the dilepton invariant mass is less than 20 GeV. For a Higgs boson with GeV, a confidence level (CL) exclusion observed (expected) limit is 6.7 () times the standard model prediction. Additionally, a search for process is presented, and an upper limit at CL on the branching fraction of the decay for the 125 GeV Higgs boson is set at
Fermionic Decays of SM Higgs
No full textIn this document I present an overview of the recent results published by ATLAS and CMS collaborations on the searches for SM Higgs boson decay to fermions. The document summarizes the status of the analyses up to September of 2014 and contains the results of pp collision Data at = 7 and 8 TeV. Searches for H , H to bb, H and ttH processes are presented
Constraints on the Higgs-charm coupling by CMS
No full textThe discovery of the Higgs~(H) boson ten years ago and successful
measurements of its couplings to third generation fermions by ATLAS
and CMS experiments mark great milestones for the field of High Energy
Physics. The much weaker coupling of the H boson to second generation
quarks predicted by the standard model (SM) makes the measurement of
the H-charm coupling much more challenging. With the full Run-2 data
collected at the LHC a lot of progress has been made by the CMS
Collaboration to constrain this coupling. In this report I present the
latest results of the direct and indirect measurements of the H-charm
coupling by CMS. Direct measurements are performed by searching for
the decay. It is done in gluon fusion and VH
production modes with stronger limits coming from VH mode,
at 95\% CL. In the ggH channel the
limit is set at . Indirect constraints on
the charm coupling come from the measurement of the H boson
distribution, which leads to a limit of . A~rare H
boson decay, , is also searched for at CMS,
though giving a limited sensitivity of x SM. Prospects for
future measurements at HL-LHC are also discussed. From the projections
it seems feasible to constrain the H-charm coupling better than 2
times the SM value
Neuroprotective effect of L-carnitine. Focus on changing mitochondrial function
No full textIn this study, the neuroprotective effect of L-carnitine administered per os in a dose of 25 mg/kg-800 mg/kg was evaluated. The effects of L-carnitine on changes in mitochondrial function were also studie
Endothelotropic activity of 4-hydroxy-3,5-di-tret-butylcinnamic acid in the conditions of experimental cerebral ischemia
No full textThe aim of the study was to evaluate the endothelioprotective activity of 4-hydroxy-3,5-di-tret-butylcinnamic acid in conditions of experimental cerebral ischemia. The brain ischemia was reproduced by the method of irreversible right-sided thermocoagulation of the middle cerebral artery. As comparative drugs, mexidol (30 mg/kg) and sulodexide (30 U/kg) were use
X-ray polarization in relativistic jets
No full textWe investigate the polarization properties of Comptonized X-rays from relativistic jets in active galactic nuclei (AGN) using Monte Carlo simulations. We consider three scenarios commonly proposed for the observed X-ray emission in AGN: Compton scattering of blackbody photons emitted from an accretion disc; scattering of cosmic microwave background (CMB) photons and self-Comptonization of intrinsically polarized synchrotron photons emitted by jet electrons. Our simulations show that for Comptonization of disc and CMB photons, the degree of polarization of the scattered photons increases with the viewing inclination angle with respect to the jet axis. In both cases, the maximum linear polarization is ≈20 per cent. In the case of synchrotron self-Comptonization (SSC), we find that the resulting X-ray polarization depends strongly on the seed synchrotron photon injection site, with typical fractional polarizations P≈ 10–20 per cent when synchrotron emission is localized near the jet base, while P≈ 20–70 per cent for the case of uniform emission throughout the jet. These results indicate that X-ray polarimetry may be capable of providing unique clues to identify the location of particle acceleration sites in relativistic jets. In particular, if synchrotron photons are emitted quasi-uniformly throughout a jet, then the observed degree of X-ray polarization may be sufficiently different for each of the competing X-ray emission mechanisms (synchrotron, SSC or external Comptonization) to determine which is the dominant process. However, X-ray polarimetry alone is unlikely to be able to distinguish between disc and CMB Comptonization
Laparoscopic cytoreductive surgery for metastatic colon cancer – how to improve treatment strategy
No full textBackground: Colon cancer (CC) one of the most common oncological disease in World. Up to 30% patients in Russia have metastatic CC at first visiting to oncologist. The treatment results still controversial. Nowadays, minimally invasive laparoscopic precision technique allowed extending the indication for cytoreductive surgery even in patients with severe comorbidities. Materials and methods: 89 patients with colon cancer (T1-4a) and curable synchronous distant metastases include in study. All patients underwent cytoreductive surgery with primary tumor resection. In study group (44) we performed laparoscopic surgery, in main group (45) – open surgery procedure. The groups were similar by sex, age, tumor localization and histological structure, comorbidities. Results: R0 resection performed 27% patients. The average number of lymph node removal was similar 13 and 12 respectively. Average operation time was significantly longer in study group 210 vs 120 min. In study group blood loss was lower: 300 mL vs 1200 mL. Postoperative patient recovery shorter after laparoscopic surgery (p < 0.05): time to activation 2.2 vs 3.9 days; time to first peristalsis – 1.8 vs 4.5 days; first bowel movement – 3.4 vs 4.8 days; first food taken – 2.9 vs 3.9 days. Shorter time of analgesics intake – 2.3 vs 4.4 days, p < 0.05. Hospital stay shorter: 9.3 vs 13.4 days, p = 0.05. Time to start chemotherapy reduced since 27.5 to 14.7 days, p < 0.05. Postoperative complications lower in study group: 6.8 vs 17.8%, p = 0.05. Kaplan–Meier 2-year overall survival were similar: 69.5% vs 61.6%, p = 0.96. Conclusion: Laparoscopic cytoreductive surgery for metastatic CC is safe, minimized surgical trauma and speed up patient recovery. Resumo: Fundamento: Câncer de cólon (CC) é uma das doenças oncológicas mais comuns no mundo. Até 30% dos pacientes na Rússia têm CC metastático na primeira visita ao oncologista. Os resultados do tratamento ainda são controversos. Atualmente, a técnica de precisão laparoscópica minimamente invasiva permitiu estender a indicação para a cirurgia citorredutora mesmo em pacientes com comorbidades graves. Materiais e métodos: 89 pacientes com câncer de cólon (T1-4a) e metástases distantes síncronas curáveis foram incluídos no estudo. Todos os pacientes foram submetidos à cirurgia citorredutora com ressecção do tumor primário. No grupo de estudo (44) realizamos cirurgia laparoscópica, no grupo principal (45), a cirurgia aberta. Os grupos eram semelhantes em relação à sexo, idade, localização e estrutura histológica do tumor, e comorbidades. Resultados: A ressecção R0 foi realizada em 27% dos pacientes. O número médio de remoção de linfonodos foi similar, 13 e 12, respectivamente. O tempo médio de cirurgia foi significativamente mais longo no grupo de estudo, 210 versus 120 min. A perda de sangue foi menor no grupo de estudo: 300 mL versus 1200 mL. A recuperação pós-operatória foi mais curta após a cirurgia laparoscópica (p < 0,05): tempo de ativação - 2,2 vs. 3,9 dias; tempo até o primeiro peristaltismo - 1,8 vs. 4,5 dias; primeiro movimento intestinal - 3.4 vs. 4.8 dias; primeiro alimento consumido - 2.9 vs. 3.9 dias. Menor tempo de ingestão de analgésicos - 2,3 versus 4,4 dias, p < 0,05; menor tempo de hospitalização: 9,3 vs. 13,4 dias, p = 0,05. O tempo para iniciar a quimioterapia foi reduzido de 27,5 para 14,7 dias, p < 0,05. Complicações pós-operatórias menores no grupo de estudo: 6,8 vs. 17,8%, p = 0,05. A sobrevivência global de Kaplan–Meier aos 2 anos foi semelhante: 69,5% vs. 61,6%, p = 0,96. Conclusão: A cirurgia citorredutora laparoscópica para CC metastático é segura, minimiza o trauma cirúrgico e acelera a recuperação do paciente. Keywords: Laparoscopic surgery for colorectal cancer, Cytoreductive surgery, Metastatic colorectal cancer, Palavras-chave: Cirurgia laparoscópica para câncer colorretal, Cirurgia citorredutora, Câncer colorretal metastátic
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