1,140 research outputs found
Oral History Interview with Nancy Lieberman, November 8, 2012
No full textInterview with Nancy Lieberman, a sports broadcast journalist. The interview includes biographical information about her life growing up in New York, her time on the first women's Olympic basketball team, and her career as a coach, author, and journalist on ESPN
Replication Data for Do online newspapers promote or undermine nation‐building in divided societies? Evidence from Africa
No full textReplication data and code to produce tables and figures: Data include scraped newspaper articles and associated comments from Nigeria's the Vanguard online newspaper and South Africa's Sowetan online. See article for further descriptions and consult readme.txt file first
New Age Violin: From Tradition to Innovation
No full text Julie Lyonn Lieberman, author of Blues Fiddle and New Age Violin, is equally at home playing jazz violin, Irish music, C & W, bluegrass, blues, New Age, and classical. A singer and composer as well, her music has been heard in several off-Broadway shows, and numerous music festivals, concert halls, clubs, colleges, and radio stations throughout the East Coast. </jats:p
Andrew Carnegie, World Making and the Logic of Contemporary Entrepreneurial Philanthropy
No full textThis paper focuses on the relationship between the business and philanthropic endeavours of world-making entrepreneurs; asking why, how and to what ends these individuals seek to extend their reach in society beyond business. We present an original model of entrepreneurial philanthropy which demonstrates how investment in philanthropic projects can yield positive returns in cultural, social and symbolic capital, which in turn may lead to growth in economic capital. The interpretive power of the model is demonstrated through analysis of the career of Andrew Carnegie, whose story, far from reducing to one of earning a fortune then giving it away, is revealed as more complex and more unified. His philanthropy raised his stock within the field of power, extending his influence and helping convert surplus funds into social networks, high social standing and intellectual currency, enabling him to engage in world making on a grand scale
The influence of data order on the Lieberman-Ross method
No full textA statistically exact procedure for producing lower bounds on the reliability of a parallel system of independent, exponentially failing components has been produced by Lieberman and Ross. This method uses individual component failure data to estimate system characteristics. The method has the drawback that permuting the order in which components fail (but not the inter-failure times), can alter the estimated bound, i.e., the estimates are Data Order Dependent. In this paper we investigate this dependence of the estimates, and consider the effects of a prior ordering. (Author)N6685676WR00012NAPrepared for: Chief of Naval Research, Arlington, VAhttp://archive.org/details/influenceofdatao00sch
Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing
No full textSummarySpinal and bulbar muscular atrophy (SBMA), a progressive degenerative disorder, is caused by a CAG/glutamine expansion in the androgen receptor (polyQ AR). Recent studies demonstrate that skeletal muscle is an important site of toxicity that contributes to the SBMA phenotype. Here, we sought to identify critical pathways altered in muscle that underlie disease manifestations in AR113Q mice. This led to the unanticipated identification of gene expression changes affecting regulators of carbohydrate metabolism, similar to those triggered by denervation. AR113Q muscle exhibits diminished glycolysis, altered mitochondria, and an impaired response to exercise. Strikingly, the expression of genes regulating muscle energy metabolism is rescued following peripheral polyQ AR gene silencing by antisense oligonucleotides (ASO), a therapeutic strategy that alleviates disease. Our data establish the occurrence of a metabolic imbalance in SBMA muscle triggered by peripheral expression of the polyQ AR and indicate that alterations in energy utilization contribute to non-neuronal disease manifestations
Essentials of medical biochemistry
No full textIncludes indexes.dental bookfair2016Preceded by: Marks' essential medical biochemistry / Michael Lieberman, Allan Marks, Colleen Smith. c2007.Based on: Marks' basic medical biochemistry / Michael Lieberman, Allan Marks, Alisa Peet. 4th ed. c2013.ix, 622 pages :Marks’ Essentials of Medical Biochemistry takes a patient-oriented approach that links biochemistry to physiology and pathophysiology, allowing students to apply fundamental concepts to the practice of medicine. Based on the established text, Marks’ Basic Medical Biochemistry, Marks’ Essentials is streamlined to focus only on the most essential biochemical concepts, while maintaining intuitively organized chapters centered on hypothetical patient vignettes and helpful icons for smooth navigation.
• Full-color illustrations of chemical structures and biochemical pathways elucidate core concepts and enhance understanding of the text
• Hypothetical patient vignettes ensure clinical relevance and help connect biochemistry to human health and disease
• Helpful icons guide you through each chapter and identify key concepts such as signs and symptoms, clinical pearls, treatment options and outcomes, and more
• Chapter Outlines and Key Points allow readers to preview and review chapter content
• End-of-Chapter Review Questions and Summary Disease Tables highlight the take-home messages and reinforce knowledg
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Number 11 in the Katherine Anne Porter Prize in Short Fiction Series
No full textThe short stories in this rich debut collection embody in their complexity Alice Munro’s description of the short story as “a world seen in a quick, glancing light.” In chiseled and elegant prose, Lieberman conjures wildly disparate worlds. A middle aged window washer, mourning his wife and an estranged daughter, begins to grow attached to a young woman he sees through the glass; a writer, against his better judgment, pursues a new relationship with a femme fatale who years ago broke his heart; and the daughter of a Holocaust survivor struggles with the delicate decision of whether to finally ask her aging mother how it was that she survived. It is all here—the exigencies of love, of lust, the raw, unlit terrain of grief. Whether plumbing the darker depths or casting a humorous eye on a doomed relationship, these stories never force a choice between tragedy and redemption, but rather invite us into the private moments and crucibles of lives as hungry and flawed as our own. “Quiet, moving, masterfully crafted. Such are the nine stories in Venus in the Afternoon. Tehila Lieberman writes with precision, restraint, with a compassionate heart. She inhabits her characters, young or old, men or women, honestly, but without judgment, until they rise off the page and stand before us breathing and alive. New York, the Atacama desert, Amsterdam or Cuzco in Peru, the settings in Venus in the Afternoon are just as varied as the lives which they contain. A wonderful collection, one that will stay in your mind long after you have bid it goodbye.” —Miroslav Penkov, author of East of the West and judg
The"IPO-Plus": a new approach to privatization
No full textEvery approach to privatization entails tradeoffs. The chief advantage of case-by-case privatization -including sales for cash or initial public offerings (IPOs)- is efficiency. Case-by-case privatization generates revenues, gives shareholders control over managers, and provides access to capital and skills. But it is slow and does not promote widespread public participation. Voucher-based mass privatization programs, by contrast, are designed to promote equity in the distribution of wealth, through widespread participation. But they do not ensure efficiency because they may not generate revenues, bring in new capital or skills, or give shareholders control over managers. To promote equity and efficiency, the authors propose a new form of privatization -IPO-Plus- that incorporates key features of both case-by-case privatization and mass privatization. IPO-Plus promotes equity through widespread (but not mass) participation in privatization. It promotes efficiency by making privatization transparent, by fostering capital market development, and by creating independent financial institutions that would press companies to improve their financial performance. It relies not on vouchers but on the sale of low-priced public shares. It allows deferred payment for company shares as an incentive to purchase them as well as downwardly flexible share prices. Because the quality of the enterprises chosen for privatization is essential to the success of the IPO-Plus program, it is important that few enterprises targeted for IPO-Plus be published before the program is launched. This will motivate potential investors to join the program by setting up management companies, establishing public investment funds, and buying shares in them. IPO-Plus is more likely than mass privatization to create real owners. Investors in IPO-Plus are given a subsidy, but only in proportion to what they themselves choose to pay. The individual determines (up to a ceiling) how much to invest in the program. IPO-Plus is particularly appropriate where the objective is to encourage outside ownership rather than significant employee ownership. It encourages the emergence of market intermediaries and ensures the concentration of enterprise shares in investment funds. Outside ownership and concentration of share voting rights provide the basis for enterprise restructuring and economic growth.Payment Systems&Infrastructure,International Terrorism&Counterterrorism,Economic Theory&Research,Banks&Banking Reform,Municipal Financial Management,Banks&Banking Reform,Municipal Financial Management,Payment Systems&Infrastructure,Economic Theory&Research,International Terrorism&Counterterrorism
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Evolution of Hominin Forelimbs in the Context of Bipedalism
No full textThe evolution of bipedalism in the hominin lineage coincided with a major shift in the locomotion function of the forelimbs, from producing external forces in contact with the substrate in the arboreal and quadrupedal last common ancestor with chimpanzees, to producing no external forces but swinging as angular momentum counterweights to the legs in striding bipedalism. The shift in forelimb function has been an important topic of study in human evolution, with fossil forelimbs used to interpret the behavior of extinct species and the degree to which they relied on terrestrial bipedalism as a locomotion strategy. This thesis uses biomechanical models and experiments of human walking and running in three studies to investigate how forelimb variation observed in hominin fossils affect the mechanics and costs of bipedal locomotion in order to refine interpretations of the evolution of bipedalism in the hominin lineage.
The first study addressed the question, Why do humans walk with straight arms but run with bent arms? In order to answer the question an experiment was conducted with a modern human sample walking and running with both straight and bent forelimbs. The results of the study indicated that a mechanical tradeoff exists when bending the forelimb at the elbow; bent forelimbs reduce shoulder muscle torque at the cost of increased elbow muscle torque. Net metabolic rate results showed that the mechanical tradeoff favors straight forelimbs during walking, as bent forelimbs increased metabolic rate by 11%. However, the cost of running was equivalent with straight and bent forelimbs, leaving the question of why humans run with flexed elbows unanswered.
The second study addressed the effect of distal forelimb length on the muscle torques at the elbow during walking and running. An experiment was conducted with modern humans walking and running holding hand weights that moved the center of mass of the distal forelimb away from the elbow, experimentally lengthening the segment. Longer distal forelimbs increased the required elbow muscle torque for both gaits, but the effect size was approximately three times greater for running compared to walking. In the hominin fossil record a shift towards relatively shorter distal forelimbs occurred in Homo erectus, coincident with the evolution of endurance running. The results of the second study shed light on the evolution of hominin forelimbs, linking forelimb biomechanics during running to selection for shorter distal forelimbs.
The third study addressed functional scaling of forelimb swing dynamics across a range of body sizes and compared functional scaling to geometric scaling of interlimb proportions. Data from an experiment of modern human walking, combined with a theoretical scaling model of shoulder muscle function, indicated that under the constraint of similar shoulder muscle function bigger hominins require relatively shorter forelimbs compared to small variants. Extinct hominin limb proportions are well predicted by the functional scaling model, which outperforms a geometric scaling model that does not incorporate mechanical function. The results of the third study suggest that the shift to relatively short forelimbs in the genus Homo, previously interpreted as a signal of a transition from an ancestral mix of arboreal and terrestrial bipedal locomotion to obligate terrestrial bipedalism, is more simply explained as a shift to bigger body size in Homo.
The results of this thesis shed new light on the evolution of human-like walking and running and the origins of the genus Homo. Previous interpretations of hominin locomotion behavior that posit a compromised and costly bipedal gait in hominins before Homo lack biomechanical underpinnings and rely solely on morphological evidence. The results presented here provide the first mechanistic approach to understanding the evolution of hominin forelimbs and lead to the conclusion that human-like walking function evolved in Australopithecus, followed by the coincident evolution of larger body size and endurance running in the genus Homo.Human Evolutionary Biolog
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