1,721,281 research outputs found
La pittura e la traccia grafica in età evolutiva
No full textLe malattie serie dell'età pediatrica rappresentano una delle esperienze più costose in termini di limitazione delle capacità che il bambino e l'adolescente potrebbero sviluppare.
Il volume descrive esperienze di psicologia in ambiente pediatrico: le occasioni di cura presentate descrivono un paziente in movimento che gioca, lascia tracce grafiche, immagina, pensa, accanto a una coppia genitoriale che, sopravvissuta all'angoscia e alla paura di morte, convive con esse ed è creativa dei cambiamenti che le sono possibili
E' solo clownerie?
No full textLa visione di una professionalità orientata al benessere fisico, psicologico e sociale dell’individuo riguarda quelle attività il cui fondamento è la relazione di aiuto; nello svolgimento di queste attività è richiesta, ai medici, agli infermieri, agli psicologi, agli operatori volontari, una competenza professionale specifica sulle funzioni del prendersi cura e dell’accompagnare e sulla comprensione dei contenuti emozionali connessi con la patologia e l’esperienza di essa. L’espressione dei contenuti emozionali e dell’esperienza di malattia possono essere facilitati dalla clown terapia. Con il loro intervento i clown possono migliorare la qualità della vita dei pazienti e aiutarli - attraverso il gioco, la creatività, il sorriso e il riso - a comprendere ed elaborare le emozioni negative che derivano dal loro stato
Gaucher Disease: a Hyper-Hippo Syndrome?
No full textThe Gaucher Disease (GD) is a lysosomal disorder associated with mutations in the GBA1 gene, encoding the acidic β-glucocerebrosidase. GD is characterized by a wide spectrum of phenotypic manifestations, the most severe of which involve the nervous system, with massive neuronal loss and microglial proliferation. Different symptoms are also observed in individuals bearing identical GBA1 mutations, suggesting that additional players are involved in the disease.
Our hypothesis is that hyper-activation of the Hippo pathway, recently found involved in some neurodegenerative syndromes, may contribute to the dramatic outcome of the neuronopathic GD. We thus started an expression analysis of upstream and downstream Hippo pathway components in Drosophila GBA1-deficient larval and adult organs.
While some Hippo downstream targets resulted down-regulated in GBA1-deficient tissues, both in terms of transcript and protein content, Fat, an atypical cadherin upstream of the kinase complex involved in the regulation of glial and synapse development, was found up-regulated. In the light of this latter result, we are currently performing behavioural assays in flies where GBA1 expression has been silenced in glial or neuronal cells, to find out possible cross-effects. Preliminary data will be presented about the implication of the Hippo pathway in the pathogenesis of the neuronopathic GD
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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