1,721,118 research outputs found
Klinefelter’s Syndrome, From a Disabling Condition to a Variant of Normalcy
No full textKlinefelter syndrome (KS), both mosaic and non-mosaic forms, is the most frequent
genetic condition with reproductive consequences that can be diagnosed initially or
in childhood, adolescence, and adulthood. In relation to its great clinical variability,
in many cases it even remains undiagnosed. Only a few decades ago, this condition
was strongly associated with sterility, but more recently, parenthood options for KS
have broadened significantly. Despite in recent decades it has become obvious that
such a goal is highly unlikely with traditional therapy, fertility is often possible
using assisted fertility techniques. Furthermore, a newer understanding of the syndrome instructs us to early recognize the affected patients and when to normalize
the hormone imbalance, preventing health problems and improving quality of life.
The impact of a comprehensive approach to KS brings to consider this condition as
a variant of normal. However, additional conditions that may be associated with the
syndrome such as obesity, reduced bone density, sexual or psychomotor abnormalities, and developmental dyspraxia represent concerns that induced to refuse this
normal variant concept in the past.
The clinical andrologist has a key role in the diagnosis, management, treatment,
and follow-up of KS. However, other specialists such as pediatricians, geneticists,
psychiatrists, endocrinologists, psychologists, and speech therapists have central
roles in particular conditions. In the current international literature, a book considering all the clinical aspects of KS is missing. Therefore, the Klinefelter Italian Group
(KING) of the Italian Society of Andrology and Sexual Medicine (SIAMS), supported by the Springer books, asked to prominent Italian experts of the main specialties committed in KS, to develop a textbook using most recent available evidence.
Editors, Andrea Garolla, coordinator of KING, and Giovanni Corona, president of
SIAMS, included all the topics featured by experts in KS in this book. They considered epidemiology, counseling to family and patients, genetic and epigenetic factors, developmental problems, psychological features, fertility problems and
preservation, sexual function, and possible comorbidities such as osteoporosis, obesity, dyslipidemia, altered glucose metabolism, thyroid dysfunction, cancer risk,
cardiovascular problems, and strategies of management and treatment from birth to
adulthood. Finally, they strongly wanted the presence of KS patients in the book and included at the start a poetry depicting the feelings of an affected subject. Special thanks to all the authors and collaborators for their strong efforts and fruitful collaboration and for harmoniously integrating their competence
LA PREVALENZA DEL DIABETE GESTAZIONALE IN SARDEGNA: RISULTATI CON DIVERSE PROCEDURE DI SCREENING E DIAGNOSI
No full textCARATTERISTICHE TISSUTALI DEI NODULI DI ENDOMETRIOSI PROFONDA IN BASE ALLA DIFFERENTE LOCALIZZAZIONE VALUTATI PER MEZZO DELL'ECOGRAFIA TRIDIMENSIONE CON VIRTUALI ORGAN-COMPUTER-AIDED ANALYSIS (VOCAL)
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
IL TRATTAMENTO CONSERVATIVO NEL MANAGEMENT DEL PROLASSO DEGLI ORGANI PELVICI PROLASSO DEGLI ORGANI PELVICI.
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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