110 research outputs found
Author Diane Glancy discusses her first movie project and reads from a journal she is keeping about her experiences as a novice movie maker
No full textNoted author Diane Glancy discusses her first movie project and reads from a journal she is keeping about her experiences as a novice movie maker. After showing a clip from the still unfinished movie (not included here), she takes questions from the audience. Introduced by MSU Anthropology Professor Susan Applegate Krouse. Part of the Michigan State University Libraries' Michigan Writers Series
Breaking the Gender Binary: Feminism and Transgressive Female Desire in Lucía Etxebarria's Beatriz y los cuerpos celestes and La Eva futura/La letra futura
No full textThe popular texts of Spanish author Lucía Etxebarria have created a polemical social phenomenon in contemporary Spain for their blatant depiction of a world of violence, drugs, and experimental sex of the late-millennium youth culture of Generación X. These topics, along with Etxebarria's public persona and feminist ideology, have fomented much public criticism and given rise to discussion of the current status of feminism, gender norms, and women's authorship in Spain today. This article analyzes Etxebarria's novel Beatriz y los cuerpos celestes and her collection of feminist essays La Eva futura/La letra futura, demonstrating that Etxebarria's depiction of female desire and sexuality within their cultural context challenges the notion that feminism has no more to achieve and breaks the gender binary by imagining a gender-anonymous world. Beatriz delves into the life of the title character, a young woman whose experience with a dissolute social culture and her attempts to understand herself cause her to question stereotypical standards of womanhood and eroticism and to declare that she fits into no such preconceived notions. Beatriz is a literary inscription of Etxebarria's feminist ideology as posited in La Eva futura, insofar as both these texts blur the line between feminism and postfeminism and engage with consumerist culture and identity. Moreover, they construe a philosophy that pushes the boundaries of normative discourse by misciting hegemonic notions of femininity and sexuality and creating the potential for change through such mis-repetition of hegemonic discourse. Ultimately, Etxebarria's work strives for a transgressive, unbound, and fluid female desire that is in continuous reconstruction and defies heteronormative definition
Legacy matters: How academic repositories can fulfill emotional requests
No full textAm informal article about the intrinsically archival nature of these items and how they affected two patrons on a deeply emotional level.Embargoed Restriction set for Item 98349 on 2017-02-28T17:37:22Z with date 2017-04-07 by [email protected] by Kelly Applegate ([email protected]) on 2017-02-28T17:43:32Z
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Legacy Matters.pdf: 193119 bytes, checksum: 72a2c485435f8b427d81786c7dafdf96 (MD5)Made available in DSpace on 2017-03-02T22:38:46Z (GMT). No. of bitstreams: 1
Legacy Matters.pdf: 193119 bytes, checksum: 72a2c485435f8b427d81786c7dafdf96 (MD5)
Previous issue date: 2016-10-06Embargo set by: Helen Sheridan for item 98349
Lift date: 2017-04-07T05:00:00Z
Reason: As per agreement with Library Journal author contract, which states a six month embargo.Embargoed Restriction Lifted for Item 98349 on 2017-04-07T09:15:14Z
A Recording Project Featuring Five Newly Commissioned Works for Clarinet by James Patrick Applegate
No full textabstract: ABSTRACT
This project features five new pieces for clarinet commissioned from three different composers including:
1. Rasa by Jeffrey Ouper
2. Faerie Tale Dances by Jeffrey Ouper
3. Amalgamated Widget by Tavia Sullens
4. Faerie Suite by Theresa Martin
5. Time Lapse by Theresa Martin
Faerie Suite and Amalgamated Widget are for unaccompanied clarinet; Time Lapse is a trio for clarinet, bass clarinet, and piano; Faerie Tale Dances is a trio for E-flat clarinet, sopranino recorder, and toy piano; and Rasa is a quartet for E-flat clarinet, two A clarinets, and bass clarinet. These pieces challenge the performer in various ways, including complex rhythm, use of extended techniques such as glissando, flutter tongue, and circular breathing, and synthetic and non-traditional scales. The composers were given guidelines prior to the compositional process to create works with a thematic connection to mythology, folklore, or fairy tales, and inspired by dance and non-western or traditional harmonies and idioms. This document offers background information about the composers and the works, and a performance guide is included for each. This guide provides recommendations and suggestions for each piece. Also included are interviews with each of the composers. Accompanying this document are recordings of each of the five pieces, performed by the author.Dissertation/ThesisRasa AudioAmalgamated Widget AudioFaerie Tale Dances- I. The Stroke of Midnight AudioFaerie Tale Dances- II. Mirror, Mirror AudioFaerie Tale Dances- III. Pixie Dust AudioFaerie Suite- I. Titania AudioFaerie Suite- II. Eurydice AudioFaerie Suite- III. LoreleiFaeie Suite- IV. Lugh's DanceTime LapseDoctoral Dissertation Music 201
Author Index
No full textAuthor Index (8 pages)
A-Z
A
Abeles, S., 18,35 Aburto, S., 22, 34 Acheson, K. A., 311, 326 Adams, N. E., 173,176 Adams, P. T., 47, 75 Aickin, M., 217, 257 Airasian, P. W., 283, 303 Alabama State Board of Education, 81, 129 American Educational Research Association, 8, 14, 28, 34, 83, 85, 86, 88, 97, 98, 102, 105, 106, 107, 109, 119, 125, 126, 127,129,227,246,247,256,267,268, 269, 277, 282, 286, 298, 300, 359, 375 American Psychological Association, 8, 14, 28,34,83, 85, 86, 88, 92, 97, 98 , 102, 105, 106, 107, 109, 119, 125, 126, 127, 129,227,246,247,256,267,268,269, 277,282, 286, 298, 300, 359, 375 Anderson, B. D., 146, 176 Anderson, C. S., 174, 176 Angoff, W. H., 285, 287, 300 Applegate, J. M., 49, 75 Armor, D., 173,176 Aylesworth, M. S., 55, 75 Ayres, Q. W., 105, 129
...
YZ
Yalow, E., 243, 259 Yalow, E. S., 87, 91, 92, 136, 284,306 Young, R., 308, 327 Zellman, G., 173, 176 Zieky, M. J., 118, 132 Zigmond, N., 284,302 Zimmerman, D. W., 289, 290, 306 Zimowski, M., 290, 291, 30
Recollections of my boyhood,
No full textThe author went overland to Oregon in 1843.Illustrated cover.Mode of access: Internet
Impact of dietary tomato intake on prostate cancer throughout the course of disease development and progression in a transgenic mouse model
No full textDespite decreasing trends of overall diagnosis, prostate cancer (PCa) is the most commonly diagnosed male cancer in the United States. However, the decrease in total and early stage PCa masks the disproportionate increased trend in the incidence of advanced stage disease. Interestingly, evidence has shown that overweight and obesity, an affliction affecting nearly 80% of adult males in the United States, increases the risk for advanced PCa. The standard treatment for advanced or metastatic PCa involves pharmacological depletion of growth-stimulating hormones by androgen deprivation therapy (ADT). Despite initial tumor regression, PCa inevitably recurs within 2-3 years and becomes known as castration-resistant PCa (CRPC), a terminal and treatment-resistant disease. Second only to potatoes, tomatoes are widely consumed in a variety of forms throughout the United States. Abundant epidemiological and pre-clinical evidence exists to show that physiologically relevant levels of dietary tomato intake reduce the risk for primary PCa, but a gap in knowledge exists regarding a potential role for tomato in protecting against the emergence of CRPC or the increased risk of advanced PCa with overweight/obesity.
In Chapter 1, I conducted a literature review to provide an in-depth background regarding prostate physiology, PCa development and progression, PCa treatment, and the emergence of CRPC and treatment-resistant disease. I also included a review of the current pool of literature reporting outcomes of tomato and tomato carotenoids on risks and mechanisms associated with PCa.
In Chapter 2, we aimed to investigate whether dietary lyophilized tomato powder (TP) or lycopene impacted the molecular expression of castrate-resistant tumors. In two independent studies using ultrasound imaging to monitor in vivo tumor growth, we previously showed that neither dietary tomato nor supplementation of its primary bioactive, lycopene, inhibited the emergence or reduced the growth of CRPC in a mouse model of PCa (transgenic adenocarcinoma of the mouse prostate; TRAMP), castrated to mimic ADT. In this chapter, we aimed to investigate the molecular underpinnings of individual CRPC tumors with the hypothesis that dietary tomato or lycopene supplementation impacted the expression of biomarkers associated with aggressive tumors. As a secondary analysis, we also sought to identify common variables between seemingly heterogeneous CRPC tumors that could provide insight into the molecular determinants of potentially diet-dependent and diet-independent effects of CRPC variants on tumor growth. Immunohistochemical results showed phenotypic variation of TRAMP tumors similar to that described in human tumors (mixed androgen-sensitive and androgen-resistant phenotypes), and divergent growth patterns between individual TRAMP tumors was evident. Molecular analyses revealed heterogeneity of protein and gene expression between diets and across animals from both studies, with TP dietary interventions reducing the expression of molecular markers associated with androgen signaling (AR) and inflammation (IL-6, pSTAT3-Y705). No effects were observed by lycopene supplementation. Between tumor phenotypes, there was differential expression of genes related to androgen signaling (srd5a1, srd5a2) and angiogenesis (vegfa).
In Chapter 3, we hypothesized that a “Western”-style diet (high in both fat and sugar) would induce weight gain and subsequently promote tumor growth in TRAMP mice. In addition, we hypothesized that dietary tomato would attenuate the carcinogenic effects of diet and obesity on PCa development and progression. Four-week-old TRAMP mice were randomly assigned to consume one of four diets (n=45/diet): control (CON) or obesogenic (OB), both with and without 10% TP. Prostate tumor incidence and growth were monitored via ultrasound imaging. Mice were terminated one (W1) or four (W4) weeks following tumor development to assess early and later molecular changes associated with inflammation and angiogenesis in tumors. Regardless of TP, OB diets led to greater body weight over time, greater tumor incidence, earlier age at tumor onset, higher body weight at tumor detection, and greater post-mortem periprostatic adipose weight. TP did not affect tumor development in lean animals (CON diets), but TP was associated with a 130% reduction in PCa risk when incorporated into the OB diet. After controlling for diets, weight gain from randomization to time of tumor detection was proportionate to an increased PCa risk (each 1 g increase in body weight was associated with a 9% increased risk for tumor development; proportionally, each 5 g/m2 body mass index increase in men is associated with an 8% increased risk for advanced PCa) and larger tumor volumes over time. There were no differences between diets for tumor volume at detection, tumor growth rate, or tumor weight at euthanasia. TP inclusion in CON and OB diets reduced in vivo tumor blood perfusion over time compared with blood perfusion of tumors from non-TP-fed animals, measured by ultrasound microvessel imaging techniques. Immunohistochemical analysis of tumor sections showed that OB diets were associated with increased irregularity of blood vessel lumens, and that the inclusion of TP in the OB diet led to improvements in lumen regularity scores. Intratumoral inflammatory markers (leptin, IL-6, pSTAT3-Y705) were not significantly increased by OB diets, but TP led to reductions in IL-6 and pSTAT3-Y705 over time.
This work has demonstrated that tomato consistently interacts with the prostate tumor microenvironment, but the magnitude of effect may be dependent on stage of tumor progression. Chapter 2 results suggested a minor role for TP in reducing the expression of growth-promoting molecules in CRPC, which has the potential to translate to clinical significance over time. Chapter 3 demonstrated that both Western-modeled diets and weight gain induced by these diets was associated with greater PCa risk at a rate proportionate to the increased risk of developing advanced PCa by weight seen in humans. Moreover, this increased risk by obesogenic diets and weight gain was attenuated by 10% TP. Marginal effects were observed by TP reduction of markers of angiogenesis and inflammation; however, we conclude that further exploration of alternative mechanisms contributing to the pro-tumorigenic effects of obesity on PCa development and progression are necessary. Data from these studies therefore suggest a potential role for tomato intake in the reducing the risk of PCa, especially within current American dietary patterns and sedentary habits that promote obesity. A more modest effect by TP was demonstrated in CRPC tumors, encouraging healthy dietary patterns that include tomatoes throughout cancer treatments to maximize potential adjuvant effects. Ongoing work is exploring the impact of TP on in vivo measurements of prostate tumor metabolism and angiogenesis, and further studies should evaluate additional differences within the tumor microenvironment using high-throughput analysis techniques to identify at which point(s) TP interacts with which pathway(s). In summary, this dissertation has contributed novel findings to previously unexplored effects of tomato on different stages of PCa.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2022-08-01The student, Catherine Applegate, accepted the attached license on 2020-07-10 at 14:24.The student, Catherine Applegate, submitted this Dissertation for approval on 2020-07-10 at 14:32.This Dissertation was approved for publication on 2020-07-13 at 15:11.DSpace SAF Submission Ingestion Package generated from Vireo submission #15571 on 2020-10-02 at 15:32:28Made available in DSpace on 2020-10-07T22:44:31Z (GMT). No. of bitstreams: 2
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Previous issue date: 2020-07-13Embargo set by: Seth Robbins for item 116223
Lift date: 2022-10-07T22:44:53Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemAuthor requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Onl
Introducing the Author-ity Exporter, and a case study of geo-temporal movement of authors
No full textWe introduce a web service, Author-ity Exporter, that permits searching and exporting data from Author-ity -- a database that has PubMed author names disambiguated with a high degree of accuracy [1]. Each author is represented by a cluster of papers annotated by publication count, time-span, affiliations, topics, journals, co-authors, citations as well as imputed data from MapAffil [2], Genni [3], and Ethnea [4] and links to their NIH/NSF grants and USPTO patents; and we have plans for more. This service should enable and simplify new types of author-centered bibliometric analyses with a unique strength in funding, geography, and diversity (gender, ethnicity, and professional age). We also present an illustrative case study of modeling of authors’ career movements to and from a specific city based on data retrieved from Author-ity Exporter. The service (and the R code used in the case study) are available at http://abel.ischool.illinois.edu/cgi-bin/exporter/search.pl.Submitted by Vetle Torvik ([email protected]) on 2016-09-20T18:19:36Z
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Previous issue date: 2016-10-14Updated second author's name from Fegley, Brent D. to Fegley, Brent David to match his dissertation entry in IDEALS. Change made by [email protected] on 2016/11/21 at 11:47AM.NIH P01AG039347Ope
LIS Accreditation: Why and What Next?
No full textThis article locates library and information science (LIS) program accreditation in a professional and sociological context and describes past, current, and future initiatives to ensure that accreditation standards and procedures acknowledge, assess, and support the skills, knowledge, and attitudes that LIS professionals need. The author has worked closely with Dr. Smith on the American Library Association (ALA) Committee on Accreditation
Deconstructing Faculty Status: Research and Assumptions
No full textThis post-peer-review, pre-copyedit version of the article submitted to IUPUI ScholarWorks as part of the OASIS Project.Arguments for faculty status have traditionally been based upon a comparative model: librarians want their roles to be compared to those of faculty, not administrators. The author of this article, however, finds almost no empirical research on the status, roles, and benefits of faculty, librarians, and administrators to support this model. She posits several alternative approaches to the faculty status issue
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