41 research outputs found
Re-envisioning Cyprus
No full textExhibition catalogue / edited volumeArtists and academics join forces in a common effort to “re-envision” Cyprus. The result is anedited volume and a photography & multimedia exhibition.
The authors of “Re-envisioning Cyprus” come from different disciplines – such asanthropology, social sciences, art history, literature, cultural theory and visual arts. They usevarious methods – some excavate past images, and some produce or comment on newones. They exploit all kinds of materials – such as press, studio or vernacular photos, statues,landmarks, urban constructions and religious spaces. What united them is first their wish tosee Cyprus with their own eyes and with their own minds, rather than through officialisinglenses, or narratives. Second, they are rather interested in photography, and how it can helpour conceptual understanding of the island.
The images each author has selected or produced will be included in the accompaniedexhibition. The exhibition will feature the work of visual artists from Cyprus and abroad andwill be opened by the Minister of Education and Culture, Mr. Andreas Demetriou onWednesday, December 8th at 8pm.
Participating Authors and Artists: Loucas Antoniou, Melita Couta, Johanna Diehl, AnandanaKapur, Phanos Kyriacou, Orestis Lambrou, Chrystalleni Loizidou, Peter Loizos, MiriamPaeslack, Haris Pellapaisiotis, Nicos Phillipou, Sondra Sainsbury, Stefanos Stefanides,Theopisti Stylianou-Lambert, Constantinos Taliotis, Demetris Taliotis and Ellene Tsangarides.
The exhibition is organized by the University of Nicosia (organizer) and the Cyprus Universityof Technology (partner) and is part of the celebration of the 50th year anniversary of Cyprus.The book is published by the University of Nicosia Press and will be available at theexhibition opening.
Editors/ Curators:Peter Loizos (London School of Economics)Nicos Philippou (University of Nicosia)Theopisti Stylianou-Lambert (Cyprus University of Technology)Government of Cyprus, University of Nicosi
High intesity exercise-induced muscle damage: the role of growth factors
No full textSkeletal muscle damage results in increased expression of insulin-like growth factor-1 (IGF-1), which has been associated both with mitogenic and myogenicmechanisms involved in muscle regeneration. Different IGF-1 isoforms (IGF-1Ea,IGF-1Eb and MGF) have been proposed to have varying functions in muscle repairand growth. To gain insight into the potentially differential actions of IGF-1 isoformsin the regulation of muscle regeneration, the time course of their expressions wasassessed, at both mRNA and protein levels, after exercise-induced muscle damage inhumans. In addition, synthetic MGF E peptide signalling has been characterized inC2C12 myoblasts, in vitro. Changes in muscle’s mechanical properties andinflammatory-related factors in the blood associated with muscle damage were alsoassessed. Ten healthy men volunteers performed 50 maximal eccentric muscleactions using the quadriceps muscles and muscle biopsy samples were taken from theexercised muscles before and 6 h, 2, 5 and 16 days post-exercise. Muscle damagewas documented by its clinical and biochemical markers post exercise, while it wascharacterized by systemic cytokine responses and specific functional adaptations.Analyses of muscle biopsy samples revealed a rapid and transient up-regulation ofMGF mRNA expression, which was followed by a prolonged increase of IGF-1Eaand IGF-1Eb mRNA expression. Patterns similar to those for mRNA expressionwere detected for MGF and IGF-1Ea expression at the protein level. The action ofsynthetic MGF E peptide differed from that of mature IGF-1 since its proliferativeeffect on C2C12 myoblast-like cells was not blocked by an anti-IGF-1 receptorneutralizing antibody and, in contrast to mature IGF-1, it activated only ERK1/2 andnot Akt phosphorylation. It was concluded that the differential expression profile ofIGF-1 isoforms in vivo and the the possible IGF-1R – independent MGF E peptidesignalling in skeletal muscle-like cells support the notion of a specific andautonomous function of MGF on skeletal muscle regeneration.Η βλάβη του σκελετικού μυός οδηγεί σε αυξημένη έκφραση του ινσουλινομιμητικούαυξητικού παράγοντα-1 (IGF-1), ο οποίος έχει συνδεθεί τόσο με τους μιτογόνους όσο καιμε τους μυογόνους μηχανισμούς που εμπλέκονται στη μυϊκή αναγέννηση. Διαφορετικέςισομορφές του IGF-1 (IGF-1Ea, IGF-1Eb και MGF) έχει προταθεί ότι έχουν ποικίλεςλειτουργίες στην επιδιόρθωση και την αύξηση του μυός. Με σκοπό τη διερεύνηση τωνενδεχομένως διαφορετικών δράσεων των ισομορφών του IGF-1 στη ρύθμιση της μυϊκήςαναγέννησης, στην παρούσα μελέτη εξετάστηκε το χρονοδιάγραμμα της έκφρασής τους,τόσο σε επίπεδο mRNA όσο και πρωτεΐνης, μετά από ασκησιογενή μυϊκή βλάβη στονανθρώπινο σκελετικό μυ. Επιπλέον, χαρακτηρίστηκε η σηματοδότηση ενός συνθετικούπεπτιδίου Ε του MGF σε καλλιέργειες μυοβλαστών C2C12. Αλλαγές στις μηχανικέςιδιότητες του μυός και παράγοντες στο αίμα που σχετίζονται με τη φλεγμονήαξιολογήθηκαν, επίσης, μετά τη μυϊκή βλάβη. Δέκα υγιείς άνδρες εθελοντές εκτέλεσαν 50μέγιστες έκκεντρες συστολές, χρησιμοποιώντας τον τετρακέφαλο μηριαίο μυ και δείγματαμυϊκών βιοψιών λήφθηκαν από τους ασκηθέντες μυς πριν και 6 ώρες, 2, 5 και 16 ημέρεςμετά την άσκηση. Η μυϊκή βλάβη τεκμηριώθηκε με τους κλινικούς και βιοχημικούςδείκτες της μετά την άσκηση, ενώ χαρακτηρίστηκε από μεταβολές κυτταροκινών στο αίμακαι συγκεκριμένες λειτουργικές προσαρμογές του μυός. Οι αναλύσεις των δειγμάτων τωνμυϊκών βιοψιών αποκάλυψαν μια άμεση και παροδική αύξηση της έκφρασης του MGF σεεπίπεδο mRNA, η οποία ακολουθήθηκε από μια παρατεταμένη αύξηση του mRNA τωνισομορφών IGF-1Ea και IGF-1Eb. Παρόμοια πρότυπα με εκείνα της έκφρασης σε επίπεδοmRNA ανιχνεύθηκαν για τις ισομορφές MGF και IGF-1Ea σε πρωτεϊνικό επίπεδο. Ηδράση του συνθετικού πεπτιδίου Ε του MGF διέφερε από αυτή του ώριμου IGF-1,δεδομένου ότι η πολλαπλασιαστική επίδρασή του στα μυοβλαστικού τύπου κύτταραC2C12 δεν εμποδίστηκε από ένα αντίσωμα που αδρανοποίησε τον υποδοχέα του IGF-1και, σε αντίθεση με το ώριμο πεπτίδιο του IGF-1, ενεργοποίησε τη φωσφορυλίωση μόνοτων ERK1/2 και όχι και της Akt. Συμπεραίνεται ότι, το διαφορικό πρότυπο έκφρασης τωνισομορφών του IGF-1 στον ανθρώπινο σκελετικό μυ και η πιθανώς ανεξάρτητη από τονυποδοχέα του IGF-1 σηματοδότηση του συνθετικού πεπτιδίου Ε του MGF στα κύτταραC2C12 υποστηρίζουν την αντίληψη μιας ειδικής και αυτόνομης λειτουργίας του MGFστην αναγέννηση του σκελετικού μυός
Challenging the hierarchies of the city: Oscar Niemeyer\u92s mid-twentieth-century residential buildings
No full textWorkshop 4. Session 4.1: Design and modernit
Effect of resistance training through in-person and teleconferencing sessions in rehabilitation of acute stroke patients
No full textObjective: To determine whether application of a strength training regimen yields measurable results on stroke survivors and compare different methods for the proposed intervention.
Design, Patients and Methods: Ninety stroke patients were recruited from the neurological clinic of a local third-level clinic. Sixty patients participated in a strength training regimen with trainings taking place 3 times a week for 12 weeks with the use of resistance bands. Thirty of these patients were given face-to-face sessions and 30 patients were given trainings through an on-line platform. The last 30 patients who comprised the control group only followed usual care after the stroke.
Results: The applied strength regimen had a statistically significant effect on Visual Analog Scale scores of stroke patients who received it (p = 0.009), as well as in the teleconferencing group (p = 0.004). The measured arteriovenous oxygen difference was elevated for stroke patients who received the intervention as a whole (p = 0.007). Patients who were trained in person and the ones who were trained via teleconferencing yielded similar results as evaluated through the VAS index.
Discussion and Conclusion: Administration of strength training 3 times weekly for 12 weeks to stroke patients yielded measurable results in terms of general function and quality of life
Insulin-Like Growth Factor-1 Bioregulation System Abnormalities Another Explanatory Mechanism of Exercise Intolerance in Heart Failure
No full textTHE IMPACT OF MANUAL THERAPY TECHNIQUES ON PAIN, DISABILITY AND IL-1B LEVELS IN PATIENTS WITH CHRONIC CERVICAL PAIN
No full textBackground: Chronic neck pain is a common musculoskeletal dysfunction, and Manual Therapy is one of the effective treatment modalities, but underlying mechanisms of action are unclear. The study's purpose was to investigate the short-term effect of mobilization-manipulations on patient's symptoms and to detect changes in the concentration of inflammatory biomarker interleukin-1b. Methods: Twenty-two patients aged 20-50 years with chronic neck pain, randomly assigned into two groups. The study group received nine sessions of a three-week Manual Therapy intervention. The control group received SHAM Manual Therapy of the same dosage. Pain and functionality measures conducted before and after the intervention via NPRS and NDI scales, respectively. Blood samples collected at baseline, after the first session and post-intervention, detecting IL-1 beta concentration, using the corresponding ELISA kit. Mixed ANOVA statistical analysis implemented for differences in the GROUP-TIME factors. Results: There was a significant statistical interaction between factors and significant main effects on pain, functionality, and IL-1 beta (p <.05). IL-1 beta was statistically significant reduced (p <.05) at second measurement for the study group, but not significantly reduced (p>.05) between second and final measurement. No statistical significance was found for the control group on any of the dependent variables across measures. Conclusion: Patients with chronic mechanical pain showed significant pain and functionality improvement after manual therapy application. The underlying mechanism of action seems to relate with a reduced IL-1b concentration of reinforcing future research at relevant pain biomarkers
Solitary Renal Metastasis Arising from a Pulmonary Adenoid Cystic Carcinoma: A Case Report and Review of the Literature
No full textAdenoid cystic carcinoma (ACC) is a malignancy affecting the salivary glands and rarely involving the lung. Due to its rarity, primary lung ACC remains incompletely understood. We herein report the case of a 57-year-old female patient who was initially diagnosed with primary lung ACC and was treated by lobectomy. Seven years later, an abdominal computed tomography scan performed in the context of surveillance revealed the presence of a solid lesion arising from the lower pole of the left kidney. The patient underwent left partial nephrectomy, and histopathology confirmed a completely excised metastatic ACC
THE IMPACT OF MANUAL THERAPY TECHNIQUES ON PAIN, DISABILITY AND IL-1B LEVELS IN PATIENTS WITH CHRONIC CERVICAL PAIN
No full textRe-envisioning Cyprus
No full textAlso in book with Title :Re-envisioning Cyprus. Nicosia: University of Nicosia Press, Loizos, P., Philippou, N., Stylianou-Lambert, T. (2010).Artists and academics join forces in a common effort to “re-envision” Cyprus. The result is anedited volume and a photography & multimedia exhibition.
The authors of “Re-envisioning Cyprus” come from different disciplines – such asanthropology, social sciences, art history, literature, cultural theory and visual arts. They usevarious methods – some excavate past images, and some produce or comment on newones. They exploit all kinds of materials – such as press, studio or vernacular photos, statues,landmarks, urban constructions and religious spaces. What united them is first their wish tosee Cyprus with their own eyes and with their own minds, rather than through officialisinglenses, or narratives. Second, they are rather interested in photography, and how it can helpour conceptual understanding of the island.
The images each author has selected or produced will be included in the accompaniedexhibition. The exhibition will feature the work of visual artists from Cyprus and abroad andwill be opened by the Minister of Education and Culture, Mr. Andreas Demetriou onWednesday, December 8th at 8pm.
Participating Authors and Artists: Loucas Antoniou, Melita Couta, Johanna Diehl, AnandanaKapur, Phanos Kyriacou, Orestis Lambrou, Chrystalleni Loizidou, Peter Loizos, MiriamPaeslack, Haris Pellapaisiotis, Nicos Phillipou, Sondra Sainsbury, Stefanos Stefanides,Theopisti Stylianou-Lambert, Constantinos Taliotis, Demetris Taliotis and Ellene Tsangarides.
The exhibition is organized by the University of Nicosia (organizer) and the Cyprus Universityof Technology (partner) and is part of the celebration of the 50th year anniversary of Cyprus.The book is published by the University of Nicosia Press and will be available at theexhibition opening.
Editors/ Curators:Peter Loizos (London School of Economics)Nicos Philippou (University of Nicosia)Theopisti Stylianou-Lambert (Cyprus University of Technology
Instructional strategies in explicating the discovery function of proof for lower secondary school students
No full textIn this paper, we report on the analysis of teaching episodes selected from our pedagogical and cognitive research on geometry teaching that illustrate how carefully-chosen instructional strategies can guide Grade 8 students to see and appreciate the discovery function of proof in geometr
