240 research outputs found
Green building management and smart automation/ Arun Solanki and Anand Nayyar, editors.
No full textIncludes bibliographical references and index."This book examines smart automation technologies which assist in energy conservation along with various performance metrics which are necessary to facilitate a building to be known as a 'green smart building'"--Green smart building: requisites, architecture, challenges, and use cases / Pijush Dutta Pramanik, National Institute of Technology Durgapur, India, Bulbul Mukherjee, Bengal Institute of Technology, Kolkata, India, Saurabh Pal, Bengal Institute of Technology, Kolkata, India -- Tanmoy Pal, Bengal Institute of Technology, Kolkata, India -- Simar Preet Singh, Thapar Institute of Engineering and Technology, Patiala, India -- A comprehensive overview of IoT based green buildings: issues, challenges and opportunities -- Rajalakshmi Krishnamurthi, Jaypee Institute of Information Technology, India / Dhanalekshmi G, Jaypee Institute of Information Technology, India -- IoT-based green building- towards an energy-efficient future / Rachna Jain, Bharati Vidyapeeth's College of Engineering, India, Vaibhav Goel, Bharati Vidyapeeth's College of Engineering, India, Jusleen Rekhi, Bharati Vidyapeeth's College of Engineering, India -- Jafar Alzubi, Al-Balqa Applied University, Jordan.1 online resource
Environmental Analysis of Construction Materials: Material Specifications for Green Built Environment
No full textThere is a growing universal awareness of protecting the living and non-living environment and making enlightened decisions to achieve a sustainable development without destruction of the natural resources. In this point of view, selecting building materials according to their energy and health performances gains importance in sustainable design. 3Rs (reducing, reusing, recycling), and supplying a healthy, non-hazardous indoor air for building occupants are two important parameters of environmental life-cycle assessment for materials. Information on exposure to gases and vapors from synthetic materials made from petrochemicals, to heavy metals and pesticides, and to some combustion pollutants that cause acid rain should be determined by analyzing environmental product declarations or material specifications. After studying on building materials individually, they are analyzed in the form of tables for four different stages; manufacturing, application, usage, demolition phase. Consequently, this chapter can guide the designer and engineer to think on the elements of design and construction activity
Incorporation of curcumin in lipid based delivery systems and assessment of its bioaccessibility
No full textCurcumin, the major curcuminoid compound from turmeric (Curcuma longa) is a well-studied nutraceutical with many health promoting biological properties. The benefits of curcumin greatly dependon its solubilization (bioaccessibility) and subsequent absorption through cell lining so that it can reach systemic/general circulation. Unfortunately, curcumin has low water solubility and undergoes rapid metabolism on oral delivery. Lipids have shown to affect the absorption of poorly soluble nutraceuticals such as curcumin by enhancing solubilization in the intestinal milieu through alterations to the composition and character of the colloidal environment –e.g. vesicles, mixed micelles and micelles when delivered orally. Thus, the purpose ofthis study was to formulate threelipid-based delivery systems with curcuminoids –gel like emulsions, nanoemulsions andorganogels, and investigate their impact on in vitro solubilization or bioaccessibility. Curcumin was dissolved in MC T oil with the help of Span 20 to be used as the lipid phase. Gel-like emulsions, nanoemulsions andorganogelswere then formulated using the curcumin-MCT oil lipid phase using different types of sugar esters as organogelators and emulsifiers. The organogels and gel-like emulsions are viscoelastic in naturewith a solid dominant behaviorwhich was supported by the rheological data. Optical and fluorescence microscopic imaging helped understand the morphology ofcurcumin inthe lipidbased delivery systemsas well as the systems themselves. Digital scanning calorimetry was used to study the phase transitionsthat occurin the systems. The bioaccessibilityof the different lipid based delivery systemswas evaluated using in vitrolipolysis experiments (dynamic pH stat lipid digestion model). Results suggest that lipid based delivery systems have more bioaccessibility when compared to that of unformulated curcuminoids. The bioaccessibility of curcumin increased at least 6.4 folds when it was incorporated in a lipid based delivery system as compared to unformulated curcuminoids.O ut of the three systems tested, gel-like emulsions had the highest stability and thus can be good candidate for incorporation and delivery of curcumin.M.S.Includes bibliographical referencesby Kavitakumari H. Solank
Nanotechnology-based approaches for regenerative medicine and biosensing
No full textThe recent emergence of nanotechnology has set high expectations in many fields of science, especially in biology and medicine. Nanotechnology-based approaches are expected to solve key questions in the emerging field of regenerative medicine. Regenerative medicine essentially deals with regeneration of cells, ultimately leading to the formation of tissues and organs. For this purpose, stem cells, embryonic stem cells or adult stem cells, are thought to be ideal resources. However, many challenges need to be addressed before the full therapeutic potential of stem cells can be harnessed. Controlling the differentiation of stem cells into cells of a specific lineage is extremely vital and challenging. Addressing this challenge, in this work, novel nanotechnology-based approaches for controlling the differentiation of neural stem cells (NSCs) into neurons has been presented. Regeneration of damaged neurons, due to traumatic injuries or degenerative diseases, is extremely challenging. For this purpose, NSCs can be used as resources that can differentiate into neurons, thus having great potential in solving needs of many patients suffering from such conditions. For controlling the differentiation of stem cells, soluble cues (comprising of small molecules and biomolecules) and insoluble cues (cell-cell interactions and cell-microenvironment interactions) play a very important role. The delivery of soluble cues, such as genetic material, into stem cells is extremely challenging. The initial part of this work presents the use of nanomaterials for efficiently delivering soluble cues such as small molecules and small interfering RNA (siRNA) into NSCs for controlling their differentiation into neurons. However, for regenerative purposes, it is preferred that least amounts of the delivery vehicle be used. Thus, the following part of the thesis presents the development and applications of nanotechnology-based approaches for enhancing the differentiation of NSCs into neurons using insoluble cues. The cellular microenviroment, consisting for the extracellular matrix (ECM) was modified by the use of nanostructures, to deliver siRNA into NSCs to enhance neuronal differentiation. Nanotopography-mediated reverse uptake of only the siRNA molecules from the ECM was achieved by the NSCs. NSC differentiation was also controlled by the use of protein micropatterns, wherein the pattern geometry and size defined the fate of the NSCs. Lastly, graphene, in combination with nanoparticles was used as component of the ECM to not only enhance the differentiation of NSCs into neurons, but also align the axons of the differentiated NSCs, having significant implications for its use in regenerating injured spinal cords. The final portion of the thesis presents the applications of nanotechnology for developing highly sensitive and selective biosensors, for detecting biomarkers implicated in various diseases such as cancer and acute pancreatitis.Ph. D.Includes bibliographical referencesby Aniruddh P. Solank
Transfer Learning to Improve Breast Cancer Detection on Unannotated Screening Mammography
No full textAtomic scale investigation of grain boundary structure role on intergranular deformation in aluminium
No full textabstract: The role that grain boundary (GB) structure plays on the directional asymmetry of an intergranular crack (i.e. cleavage behaviour is favoured along one direction, while ductile behaviour along the other direction of the interface) was investigated using atomistic simulations for aluminium 〈1 1 0〉 symmetric tilt GBs. Middle-tension (M(T)) and Mode-I crack propagation specimens were used to evaluate the predictive capability of the Rice criterion. The stress–strain response of the GBs for the M(T) specimens highlighted the importance of the GB structure. The observed crack tip behaviour for certain GBs (Σ9 (2 2 1), Σ11 (3 3 2) and Σ33 (4 4 1)) with the M(T) specimen displayed an absence of directional asymmetry which is in disagreement with the Rice criterion. Moreover, in these GBs with the M(T) specimen, the dislocation emission from a GB source at a finite distance ahead of the crack tip was observed rather than from the crack tip, as suggested by the Rice criterion. In an attempt to understand discrepancy between the theoretical predictions and atomistic observations, the effect of boundary conditions (M(T), Mode-I and the edge crack) on the crack tip events was examined and it was concluded that the incipient plastic events observed were strongly influenced by the boundary conditions (i.e. activation of dislocation sources along the GB, in contrast to dislocation nucleation directly from the crack tip). In summary, these findings provide new insights into crack growth behaviour along GB interfaces and provide a physical basis for examining the role of the GB character on incipient event ahead of a crack tip and interface properties, as an input to higher scale models.This is an Author's Accepted Manuscript of an article published as Adlakha, I., Bhatia, M. A., Tschopp, M. A., & Solanki, K. N. (2014). Atomic scale investigation of grain boundary structure role on intergranular deformation in aluminium. PHILOSOPHICAL MAGAZINE, 94(30), 3445-3466. http://dx.doi.org/10.1080/14786435.2014.961585. Copyright Taylor & Francis, available online at: http://www.tandfonline.com/doi/abs/10.1080/14786435.2014.96158
Author′s reply for comment on "positive end-expiratory pressure valve malfunctioning detected by capnographic and airway pressure waveform"
No full text
A0025 An Unusual Case Presentation as Nonconvulsive Status Epilepticus: Autoimmune Encephalitis
No full textETIOLOGICAL SPECTRUM OF CIRRHOSIS IN ANAND DISTRICT, GUJARAT, INDIA
No full textIntroduction: Alcohol is considered to be a major etiological factor in western world, whereas viral etiology is considered to be predominant cause of cirrhosis in Indian subcontinent. Alcohol consumption and subsequent cirrhosis is increasingly seen in countries such as Japan and India. Early diagnosis and specific treatment for etiology can reverse the cirrhosis. Thus, we planned this study to define etiology for the development of cirrhosis.
Methodology: All the consecutive patients with cirrhosis in last 4 years (February, 2012 to November, 2016) were analyzed for etiology. They underwent for the following investigations: liver function tests, complete blood count, alcohol and drug history, HBsAg, total anti HBc, anti HCV, Alpha Feto Protein, Ferritin, Ceruloplasmin, eye check up for KF ring, α1-antitrypsin, autoimmune hepatitis profile, sonography and doppler of abdomen, 2-D echocardiography, endoscopy and liver biopsy.
Results: A total of 304 cirrhotic patients (217 males, 87 female) were included and etiologies of cirrhosis were as follows [n (%)]:Alcohol in 105 (34.53%), Non Alcoholic Fatty Liver Disease (NAFLD) in 66 (21.71%), Cryptogenic-probable NAFLD in 50 (16.44%), Hepatitis B cirrhosis (HBV) in 35 (11.53%), Hepatitis C cirrhosis (HCV) in 16 (5.26%), Cryptogenic Cirrhosis in 16 (5.26%), Autoimmune liver disease in 7 (2.30%), Metabolic causes in 6 (2%) and Budd-chiari syndrome in 3 (0.98%).
Conclusions: Alcohol remained the most common etiology of cirrhosis most commonly in males. NAFLD is also a major factor for cirrhosis, followed by HBV and HCV. Metabolic, autoimmune and vascular etiologies were seen in few patients. Most etiologies have peculiar age distribution
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