89 research outputs found
CLINICAL PROFILE OF TUBERCULOSIS PATIENTS (PULMONARY AND EXTRA-PULMONARY) PRESENTING TO A TERTIARY CARE HOSPITAL
No full textObjective: The objective of the study is to estimate the burden of tuberculosis (TB) patients, both pulmonary and extra-pulmonary, presenting to a tertiary care hospital in southern Rajasthan and to understand the resistance pattern among them.
Methods: It is a retrospective observational study. The duration of the study was 3 years (January 2021–December 2023). Data were collected from TB registers maintained by the respiratory medicine department. The inclusion criteria were all suspected TB patients (pulmonary and extra-pulmonary). Both microbiologically confirmed and clinically diagnosed TB patients were included in the study.
Results: The total number of sputum samples received of suspected pulmonary TB patients was 1923, out of which 600 (31.2%) were acid–fast bacilli (AFB) smear positive. The total number of samples received for CBNAAT testing was 1292, out of which 266 (20.59%) were CBNAAT positive. Total multidrug-resistant (MDR) TB patients were 58 (49 pulmonary TB and 9 extra-pulmonary TB (EPTB) [5 lymph, 3 pleural, and 1 bone]). The percentage of MDR-pulmonary TB patients among total sputum samples tested was 2.55%. The total number of pulmonary TB patients diagnosed was 1016 (microbiologically confirmed 866 + clinically diagnosed 150). Total EPTB patients diagnosed were 805 (microbiologically confirmed 141 + clinically diagnosed 664).
Conclusion: 31.2% of total sputum samples tested of suspected pulmonary TB patients were AFB smear positive, and 20.59% were CBNAAT positive. Most of the patients diagnosed with EPTB were diagnosed on a clincoradiological basis. The percentage of MDR–PTB among all sputum samples tested was 2.55%
Candida lung abscesses in a renal transplant recipient
No full textWe herein report a renal allograft recipient five years post transplant who had bilateral lung abscesses. The abscess grew Candida tropicalis on bronchoalveolar lavage. The patient was administered amphotericin B, but succumbed to massive hemoptysis. The case highlights a fungal complication in renal transplant and need for early suspicion and prompt therapy
CLINICAL AND MICROBIOLOGICAL PROFILE OF PATIENTS ADMITTED WITH PNEUMONIA PRESENTING TO A TERTIARY CARE HOSPITAL IN SOUTHERN RAJASTHAN
No full textObjective: Pneumonia is a leading cause of morbidity and mortality in India. This study was conducted to understand the clinical and microbiological profile of pneumonia patients presenting to our hospital and also to understand the resistance pattern among them.
Methods: It was a retrospective observational study. Duration of the study was 6 months (June 2023 to December 2023). All patients admitted with a diagnosis of pneumonia (CAP, HAP, VAP) were included in the study and data was collected from previous medical records. Only those patients with pneumonia whose sputum or BAL (bronchoalveolar lavage) culture was positive for an organism were included in the study.
Results: A total of 50 patients with pneumonia were included the study. Majority of the patients were males (72 %) with average age of 62. Community acquired pneumonia was diagnosed in 21 patients, hospital acquired pneumonia in 15 patients and ventilator associated pneumonia in 14 patients. Most common organism isolated was Klebsiella pneumoniae (36 %), followed by Acinetobacter baumannii (24 %), pseudomonas aeruginosa (16 %), E.coli (10 %) and others (14 %). Organisms isolated from hospital and ventilator associated pneumonia showed higher prevalence of carbapenem resistance than those isolated from community acquired pneumonia patients.
Conclusion: Klebsiella pneumoniae was the most common organism isolated in CAP, HAP and VAP patients in our study. The resistance pattern of Klebsiella pneumoniae showed higher prevalence of carbapenem resistance in hospital and ventilator associated pneumonia patients as compared to CAP patients.
Keywords: Pneumonia, Hospital acquired pneumonia, Ventilator Associated pneumonia, Klebsiella pneumonia
Analytical study of contents of LANL physics and cross-listed e-print archives, 1994-2002
No full textThe frontiers of physics and cross-listed e-print archives posted during the years 1994-2002 at http://www.arxiv.org/archives/physics web service of Los Alamos National Laboratory (LANL) are explored from 7770 submissions. E-print archives posted to top most six physics-cross-listed research categories besides physics (5390) are: Condensed matter (754), Quantum physics (279), Astrophysics (222), Chemical physics (129), High energy physics - Phenomenology (118), and High energy physics-Theory (100). Prominent contributors are B.G. Sidharth (India), V.V. Flambaum (Australia), Antonina N. Fedorova (Russia), and Michael G. Zeitlin (Russia). Most preferred journals for rechannelising e-print archives are Physical Review Letters, Physical Review A, Physical Review E, Nuclear Instruments and Methods A, and Journal of Chemical Physics
Bibliographics for the 983 eprints in the live archives of E-LIS : trends and status report up to 7th July 2004, based on author-self-archiving metadata
No full textThe priority for ideas and philosophy related to "Network Theory" have been traced back and documented by Braun(2004),and credit goes to Karinthy(1929).The IT has empowered to realise it, as the most practical phenomena and it is no more a humour. The OAI (Open Archives Initiatives)and ACIS (Academic Contributor Information System)are progressive in the direction ,which may lead to realise the "Collective Genius" at global level. Focus of present study is on Author-Self-Archiving (A-S-A)Metadata of the 983 Eprints in the Live Archives of the E-LIS (EPrints of Library and Information Science),which were approved till 7th July 2004.The A-S-A Metadata was used for librametric analysis. Self-explanatory bibliographics are illustrated.The highlights include: Conference papers (34%); highest approval, June 2004 (28%); published archives (76%);not refereed (52%); not in public domain (60%); highest self-archiving-author (De Robbio, Antonella).The Nos. of EPrints having single JITA domain specifications were: Theoretical and general aspects of libraries and information(27); Information use and sociology of information(80);Users,literacy and reading(13);Libraries as physical collections(30);Publishing and legal issues(57);Management(13);Industry, profession and education(36);Information sources, supports, channels(113) ; Information treatment for information services, Information functions and techniques (101); Technical services libraries, archives and museums(25); Housing technologies(1); Information technology and library technology(92); and Inter-domainery (395) i.e. having specifications of two or more than two JITA classes
Scientometric portrait of Ram Gopal Rastogi
No full textPublication productivity of Indian scientist (R.G. Rastogi) has been documented.
Scientometric analysis of 312 papers by Ram Gopal Rastogi published during 1954 to 1992 in various domains: (a) Luni -solar activity and quiet -time E & F- region (57); (b) Equatorial electric field and low and mid latitude iof:osphere (78); (c) Ionospheric E- region irregularities (19); (dj Ionospheric F- region irregularities (32); and (e) Magnetic disturbance effects on the equatorial low and mid latitude ionosphere (23) were analysed. Interdomainery contents and of the number of papers: a+b were 36; b+c and b+d were 20 each; b+e were 16;. c+e were 5; a+e were 3; d+e were 2; and a+d had only one publication. Highest collaborations were with H. Chandra (61), M.R. Deshpande (42), and G. Sethia (19) out of his total 97 collaborators. His highest productivity was during 1978 with 28 papers followed by 19 papers during 1977. The core journals preferred by him for publishing papers were: Indian Journal of Radio & Space Physics, India, and Journal of Atomic & Terrestrial Physics, UK (59 each), followed by Proceedings of the Indian Academy of Sciences, India (34). Most prolific title keywords with their frequencies were: Ionosphere (92); Equatorial (61); F-region (53); Equatorial electrojet region (40), and Magnetic equator (30)
Diagnostic utility of adenosine deaminase in exudative pleural effusions
No full textObjective: To determine the diagnostic utility of adenosine deaminase (ADA) in exudative pleural effusions of different etiologies. Setting and Design: It was an observational study conducted at a tertiary care teaching institute. Materials and Methods: Of a total of 171 pleural fluid samples, 122 were found to be exudates and were included in the study. Pleural fluid ADA was done for all included patients. Pleural fluid ADA ≥40 U/l was taken as diagnostic cut off for TB effusion. Statistical Analysis: Sensitivity, specificity positive and negative predictive value of pleural fluid ADA for diagnosing TB was calculated by using clinical calculator - 1, Richard Lowry 2001-2013. Results: There were 171 patients with pleural effusion, out of which 122 (71.8%) were found to be exudative and were studied further. There were 49 (40.1%), 36 (29.5%) and 33 (27%) cases of TB, malignancy and para pneumonic effusion respectively, whereas 4 (3.3%) cases remained undiagnosed. Median ADA values for TB, malignancy and para pneumonic effusion were 55.8 U/l (range 9.7-756 U/l), 18 U/l (6.5-81 U/l) and 25 U/l (3.4-172 U/l) respectively. Pleural fluid ADA >40U/l yielded 85.7% sensitivity, 80.8% specificity, 75% positive predictive value and 89.5% negative predictive value. Conclusion: Pleural fluid ADA remains useful in diagnosing tuberculosis pleural effusion. The median ADA for TB effusion in present cohort was 51.8 IU/ml. Pleural fluid ADA of 40 U/L yielded 89.5% negative predictive value and 75% positive predictive value. Pleural fluid ADA is cost effective and good screening test for diagnosis of TB
CLINICAL PROFILE AND SPUTUM POSITIVITY RATE OF SUSPECTED PULMONARY TUBERCULOSIS PATIENTS PRESENTING TO A TERTIARY CARE HOSPITAL IN SOUTHERN RAJASTHAN
No full textObjective: The purpose of the study is to understand the sputum acid-fast bacilli (AFB) positivity rate among suspected pulmonary tuberculosis (TB) patients presenting to tertiary care hospital in Southern Rajasthan with symptoms of chronic cough for more than 2 weeks.
Methods: It is a retrospective observational study. Data from June 2021 to March 2024 were collected from registers maintained by the respiratory medicine department and analyzed.
Results: Out of 1720 sputum samples of suspected pulmonary TB patients that were sent for microscopy 344 were AFB positive (20%) and 292 patients (16.97%) were GeneXpert positive. A total of 21 patients (1.22%) were found to have multidrug-resistant (MDR)-TB based on sputum GeneXpert testing. Most of the patients in our study were males and the sputum positivity rate was higher among diabetic and HIV-positive patients.
Conclusion: In this study out of 1720 sputum samples analyzed for suspected pulmonary TB patients, 344 were sputum AFB positive (20%) and 21 were MDR-TB (1.22%)
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