10 research outputs found
The tricuspid annular plane systolic excursion/PASP ratio’s accuracy and validity in assessing the right ventricular function: A narrative review
No full textThe tricuspid annular plane systolic excursion (TAPSE) (transthoracic apical two-chamber stretch) and pulmonary artery systolic pressure (PASP) ratio is a measure of cardiac function that is used to assess left ventricular systolic function. PASP is typically measured using a catheterization procedure, in which a small tube is inserted into a blood vessel and advanced to the pulmonary artery. A TAPSE/PASP ratio higher than 0.36 mm/mmHg has been shown in several studies to be a good sign of normal or generally well-maintained right ventricular function. It is important to note that the TAPSE/PASP ratio should be interpreted in the context of other clinical findings and should not be used as the sole indicator of cardiac function. A decrease in the TAPSEpulmonary arterial systolic pressure (PASP) ratio (i.e., (RV)-arterial uncoupling), which quantitatively depicts the function of the RV, was detected in patients with heart failure. In pulmonary arterial hypertension patients, TAPSE/PASP is linked to hemodynamics and functional class. In diseases impacting right cardiac function, the TAPSE/PASP may also be beneficial. The purpose of this review is to demonstrate how the TAPSE/PASP impacts how the (RV) functions. We believe that this is the first review on the topic written
Increased monocyte to high-density lipoprotein cholesterol ratio is associated with TIMI risk score in patients with ST-segment elevation myocardial infarction
No full textIncreased monocyte to high-density lipoprotein cholesterol ratio is associated with TIMI risk score in patients with ST-segment elevation myocardial infarction
No full textThe Contribution of Whole Blood Viscosity to the Process of Aortic Valve Sclerosis
No full text<b><i>Objective:</i></b> We aimed to investigate whether increased whole blood viscosity (WBV) could be an important factor for the occurrence of aortic valve sclerosis (AVS). <b><i>Subjects and Methods:</i></b> A total of 209 patients were enrolled in the study. WBV was calculated using the hematocrit and total plasma protein at a low shear rate (LSR) and a high shear rate (HSR). AVS was defined as irregular valve thickening and calcification (without evidence of outflow obstruction) documented by a peak transvalvular velocity &#x3c; 2.5 m/s on echocardiographic examination. The patient group consisted of 109 patients with AVS (77 females, 32 males), and 100 subjects without AVS (65 females, 35 males) were assigned to the control group. <b><i>Results:</i></b> In the AVS group, WBV values were significantly higher for HSR (17.4 ± 0.5 vs. 17.1 ± 0.7 208 s<sup>–1</sup>, <i>p</i> &#x3c; 0.001) and LSR (65.9 ± 12.5 vs. 59.7 ± 16.7 0.5 s<sup>–1</sup>, <i>p</i> = 0.002). In multivariate logistic regression analysis, WBV at HSR and LSR were independent predictors of AVS (odds ratio, OR: 2.24, 95% confidence interval, CI: 1.38–3.64, <i>p</i> = 0.001; OR: 1.026, 95% CI: 1.006–1.046, <i>p</i> = 0.01, respectively). Receiver-operating characteristic (ROC) curve analysis indicated that a WBV cutoff value of 65.4 at LSR had a sensitivity of 46.8% and a specificity of 60.0% (area under the ROC curve, AUC: 0.615, 95% CI: 0.535–0.696, <i>p</i> = 0.004), and a WBV cutoff value of 17.1 at HSR had a sensitivity of 61.5% and specificity of 53% (AUC: 0.648, 95% CI: 0.571–0.725, <i>p</i> &#x3c; 0.001) for the prediction of AVS. <b><i>Conclusion:</i></b> This study demonstrated that WBV was independently associated<b><i></i></b> with<b><i></i></b> AVS. WBV could be an indicator of inflammation and vessel remodeling without evidence of outflow obstruction.</jats:p
Association of parathyroid hormone and vitamin D with untreated hypertension: Is it different in white-coat or sustained hypertension?
No full textPrevious reports about the relationship between a high parathyroid hormone (PTH) and low vitamin D levels with blood pressure in different hypertension groups are conflicting.We studied serum PTH and vitamin D levels in white-coat (WCHT) and sustained hypertension (SHT) patients who had not been on antihypertensive treatment. We also investigated the association between serum PTH and vitamin D levels with respect to blood pressure in SHT and WCHT patients.We included 52 SHT patients (54.06 ± 9.2 years, 32 newly diagnosed and 20 previously diagnosed with SHT who had not been treated with antihypertensive medication for 3 months or more), 48 WCHT patients (53.64 ± 9.5 years), and 50 normotensive (NT) healthy controls (53.44 ± 8.4 years) in our study. In addition to routine tests, PTH and vitamin D levels were measured.Serum PTH levels were significantly higher in SHT patients not taking antihypertensive medications than in WCHT patients and NT controls (p = 0.004). Although PTH levels were higher in WCHT than in NT groups, the difference was not statistically significant. In SHT patients, PTH levels showed a positive correlation with office systolic (r = 0.363, p = 0.008), office diastolic (r = 0.282, p = 0.038), home systolic (r = 0.390, p = 0.004), and home diastolic blood pressures (r = 0.397, p = 0.003). Serum vitamin D levels were similar in SHT, WCHT and NT groups. Vitamin D levels were not associated with blood pressures in the entire study group. Furthermore, no significant relation was found between vitamin D and PTH levels in SHT and WCHT groups.PTH levels are significantly higher in untreated SHT patients than WCHT patients and NT subjects. However, vitamin D levels are similar in SHT, WCHT and NT groups. There is a significant association between PTH levels and blood pressures suggesting PTH has a role in increase of blood pressure in SHT
Pulmonery Edema Associated with Ascaris Lumbricoides in Patients with Mild Mitral Stenosis
No full textPulmonary edema associated with Ascaris lumbricoides in a patient with mild mitral stenosis: a case report
No full textAscaris lumbricoides remains the most common intestinal nematode in the world. Clinical manifestations of ascaris lumbricoides are different in each stage of the infection. We presented an unusual presentation of ascaris lumbricoides
Frequency in the anomalous origin of the left main coronary artery with angiography in a Turkish population.
No full textWe estimated the frequency of anatomic variations in origin of the left coronary artery in a Turkish population by analyzing the angiographic data of 10,042 consecutive adult patients undergoing coronary angiography. Among 10,042 adult patients, 5 (0.04%) patients (4 men and 1 woman, age range 40-74, median 58 years old) had anomalous origin of the left main coronary artery. The left main coronary artery arose from the right coronary sinus of Valsalva in 2 (0.019%) patients (both of them had a retro-aortic course), from above the left coronary sinus of Valsalva in 2 (0.019%) patients, and from above the non-coronary (posterior)-left coronary commisure in 1 (0.009%) patient. Anomalous origin of the left main coronary artery is potentially a serious condition, as it can lead to myocardial infarction and sudden cardiac death under physical exertion. Therefore, greater effort for early detection and surgical repair of this anomaly are warranted. The angiographic recognition of anomalous origin of this vessel may prove useful for physicians dealing with diagnosis and treatment of anomalies of the left main coronary artery.</p
Frequency in the anomalous origin of the left main coronary artery with angiography in a Turkish population.
No full textWe estimated the frequency of anatomic variations in origin of the left coronary artery in a Turkish population by analyzing the angiographic data of 10,042 consecutive adult patients undergoing coronary angiography. Among 10,042 adult patients, 5 (0.04%) patients (4 men and 1 woman, age range 40-74, median 58 years old) had anomalous origin of the left main coronary artery. The left main coronary artery arose from the right coronary sinus of Valsalva in 2 (0.019%) patients (both of them had a retro-aortic course), from above the left coronary sinus of Valsalva in 2 (0.019%) patients, and from above the non-coronary (posterior)-left coronary commisure in 1 (0.009%) patient. Anomalous origin of the left main coronary artery is potentially a serious condition, as it can lead to myocardial infarction and sudden cardiac death under physical exertion. Therefore, greater effort for early detection and surgical repair of this anomaly are warranted. The angiographic recognition of anomalous origin of this vessel may prove useful for physicians dealing with diagnosis and treatment of anomalies of the left main coronary artery.</p
