136,103 research outputs found

    Alp | Año 2 | Número 2

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    Prólogo para la compilación hecha en la Universidad Nacional de La Plata Gualeguay de Juan L. Ortiz | Roxana Páez Una mirada desde la alcantarilla puede ser una visión del mundo. Los textos del grotesco lingüístico de Alejandra Pizarnik | Anahí D. Mallol La infinita presencia de la República. Notas sobre Enumeración de la patria de Silvina Ocampo | Silvia Elena Loustalet y María Eugenia Straccali Aproximaciones al "testimonio sobre la desaparición de personas" durante la dictadura y la democracia argentinas | Teresa Basile Del neobarroco al plato de ajiaco: una lectura sobre De donde son los cantantes de Severo Sarduy | Carolina Sancholuz Prólogo para la compilación hecha en la Université de Angers Jerónimo de Quiroga, militar y cronista. Visión de una sociedad colonial señorial. Chile en el siglo XVII | Fernando Casanueva Variaciones poéticas sobre un emblema en La Bandera de Chile de Elvira Hernández | Catherine Pergoux-Baeza La toponimia porteña en las novelas de Ernesto Sabato | Myriam Lefort Holmberg: de vagos, mujeres y criminales | Néstor Ponce La novela policial y la narrativa chilena de los noventa: una conversación con Roberto Ampuero | Guillermo García-Corales Actividades en el marco del convenioFacultad de Humanidades y Ciencias de la Educació

    Physiological ALP activity increases post-hemodialysis.

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    Maximal (A) and physiological (C) alkaline phosphatase (ALP) activities of pre-hemodialysis (preHD) and post-hemodialysis (postHD) plasma samples were quantified. For relative ALP activity (E), physiological ALP activities were divided by maximal ALP activities for each sample. (A, C, E) The Wilcoxon matched pairs test was used for statistical analysis. (B, D, F) The scattergraph demonstrated a correlation between pre- and post-hemodialysis ALP activities in maximal (B) and physiological (D) conditions, and relative ALP activity (F). Lineal regression demonstrated a significant deviation in all cases. *** P .</p

    ALP activity analysis.

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    <p>ALP staining in untransfected hDPCs (A), AdEGFP-transfected hDPCs (B), AdShh-transfected hDPCs (C) at 14 days after gene transduction. (D) The ALP activity of untransfected, AdEGFP-transfected and AdShh-transfected hDPCs was measured with the pNPP assay at days 7, and 14 after gene transduction. (A, B, C, ×50). (n = 3 for each group, <sup>★</sup>indicates significant differences between AdShh-transfected vs. untransfected and AdEGFP-transfected, <i>p</i><0.05).</p

    Histology of alkaline phosphatase (ALP) staining.

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    <p>A reduced number of ALP-positive cells were observed in the subchondral bone (A) and necrotic regions (B). Red arrows indicate ALP-positive cells in the sclerotic (C) and healthy (D) regions.</p

    The activity of intracellular alkaline phosphatase (ALP) and histochemical detection of ALP in SAMR1 (A, C, E) and SAMP6 (B, D, F) BMSCs.

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    (A, B) ALP activity was normalized by total cellular protein. (C, D) Histochemical detection of ALP in SAMR1 and SAMP6 BMSCs for 14days treatment of fluvastatin. (E, F) SAMR1 and SAMP6 BMSCs were treated for 14days in the presence or absence of fluvastatin (SAMR1 at 0.1μM and SAMP6 at 0.5μM) and noggin (250 ng/ml). *P < 0.05.</p

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    ALP activity and mineralization assays.

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    <p>(A, B) ALP staining of BMSCs derived from type 2 diabetic and normal rats on day 7 and day 14 of culture in osteogenic medium (lower images ×50). (C) ALP activity in BMSCs derived from type 2 diabetic and normal rats measured via a pNPP assay on day 7 and day 14. (D, E) Alizarin red S staining and quantitative mineralization assay of BMSCs derived from type 2 diabetic and normal rats on day 21 of culture in osteogenic medium (lower image of D ×50) (n = 3 for each group, *p<0.05, **p<0.01 versus normal BMSCs).</p

    PENGARUH VITAMIN D TERHADAP JUMLAH OSTEOBLAS DAN EKSPRESI ALKALINE PHOSPHATASE (ALP) PADA PERGERAKAN GIGI ORTODONTI TIKUS HAMIL

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    Pasien perempuan memiliki kemungkinan untuk hamil selama melakukan perawatan ortodonti, di mana proses tersebut mempengaruhi perubahan fisiologis yang dikaitkan dengan tingkat hormon seks seperti estrogen. Saat kehamilan, seorang perempuan mengkonsumsi berbagai macam vitamin sebagai nutrisi tambahan bagi ibu dan janin yang dikandung, salah satunya adalah Vitamin D. Pada penelitian sebelumnya, pemberian Vitamin D pada pergerakan gigi ortodonti dapat mempercepatkan pergerakan gigi ortodonti karena efek stimulatori pada osteoblas yang mampu meregulasi diferensiasi dan proliferasi osteoblas. Peningkatan aktivitas osteoblastik selama pembentukan tulang ini diikuti dengan adanya peningkatan marker, Alkaline Phosphatase (ALP). Tujuan: Untuk mengetahui pengaruh Vitamin D pada jumlah osteoblas dan ekspresi ALP serta hasil penelitian ini diharapkan dapat digunakan sebagai refrensi untuk pergerakan gigi ortodonti pada tikus hamil menggunakan Vitamin D. Metode: Penelitian eksperimental laboratoris dengan rancangan penelitian post-test only group design pada 28 ekor tikus, perlakuan pemberian vitamin D per oral dengan waktu pengamatan pada hari ke-7 dan 14 pada jumlah osteoblas dan ekspresi ALP yang diukur dengan metode Hemotoxylin Eosin dan Immunohistochemistry (IHC). Hasil dianalisis dengan uji statistik ANOVA dan multiple comparison test uji Post Hoc Tukey. Hasil: Hasil menunjukkan tiada perbedaan yang signifikan (p>0.05) antara kelompok perlakuan pada waktu pengamatan hari ke-7 dan ke-14 pada jumlah osteoblas dan ekspresi ALP. Kesimpulan: Penelitian yang telah dilakukan didapatkan hasil bahwa tiada pengaruh dalam jumlah osteoblas dan ekspresi ALP pada pemberian vitamin D pada pergerakan gigi ortodonti tikus hamil dalam waktu pengamatan hari ke-7 dan 14
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