97,715 research outputs found
Joshua Davis: Author of Spare Parts
Get PDFCitation: K-State First (2016). Joshua Davis: Author of Spare Parts [Flier]. Manhattan, Kansas: K-State First.Flyer advertising Joshua Davis's author talk at Kansas State University
Steven Johnson Author Talk Poster
No full textK-State Book NetworkA poster advertising an author talk by Steven Johnson at Kansas State University on September 3, 2014. Steven Johnson's book "The Ghost Map" was the 2014-2015 common book
Simplified Thresholds for Pediatric (Pre)hypertension: One Approach to Improve Recognition and Outcome
No full textsponsorship: The clinical research activities of K. Allegaert are supported by the Agency for Innovation by Science and Technology in Flanders (IWT) through the SAFE-PEDRUG project (IWT/SBO 130033). E. Levtchenko is a senior clinical investigator of the Fund for Scientific Research, Ministry of the Flemish Community, Brussels, Belgium (Fundamental Clinical Investigatorship, 1801110 N) and is also supported by the EURenOmics consortium (grant agreement 305608). (Agency for Innovation by Science and Technology in Flanders (IWT) through the SAFE-PEDRUG project|IWT/SBO 130033, EURenOmics consortium|305608)status: Publishe
Tailored tools to improve pharmacotherapy in infants
No full textINTRODUCTION: Extensive within-population variability is the essence of neonatal pharmacology. Despite this, infants remain one of the last therapeutic orphans. Together with additional legal initiatives, tailoring of already available tools (modeling, covariates, pharmacovigilance) may significantly improve pharmacotherapy in infants. AREAS COVERED: Modeling approaches that hold the promise to improve pharmacotherapy in infants are between-compound extrapolation for compounds that undergo the same route of elimination and integration of time-varying physiology to adapt for the fast maturational changes. Besides these maturational covariates (size, age), newly emerging covariates relate to novel treatment modalities (extracorporeal circulation, hypothermia), environmental issues (microbiome, critical illness) or pharmacogenetics. All these covariates interact with the maturational variation. Finally, pharmacovigilance also needs to be tailored to the characteristics of this population. This relates to preventive strategies, signal detection and assessment of causality. EXPERT OPINION: Knowledge on pharmacotherapy in infants is lagging. Tailoring available tools to the specific characteristics (maturation) and clinical needs (newly emerging covariates) of infants is feasible but needs creativity and a multidisciplinary collaboration between modelers, academia, clinical researchers and, obviously, the public, including parents.sponsorship: K Allegaert is supported by the Fund for Scientific Research, Flanders (fundamental clinical investigatorship 1800214N) and research activities are further facilitated by an IWT-SBO project (130033). The author has no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. (Fund for Scientific Research, Flanders|1800214N, IWT-SBO project|130033)status: Publishe
Biomarkers of propofol metabolism in neonates: The quest beyond ontogeny
Get PDFsponsorship: The research activities of K Allegaert are facilitated by the agency for innovation by Science and Technology in Flanders (IWT) through the SAFEPEDRUG project (IWT/SBO 130033). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. (agency for innovation by Science and Technology in Flanders (IWT) through the SAFEPEDRUG project|IWT/SBO 130033)status: Publishe
Editorial: neonatal clinical pharmacology: a rapidly maturing discipline
No full textsponsorship: K Allegaert has been supported by the Fund for Scientific Research, Flanders (fundamental clinical investigatorship 1800214N) and his research activities are facilitated by the agency for innovation by Science and Technology in Flanders (IWT) through the SAFEPEDRUG project (IWT/SBO 130033). The research activities of John van den Anker are supported with two grants (5T32HD087969, 5U54HD090254) from the Eunice Kennedy Shriver National Institute of Child Health and Development. (Fund for Scientific Research, Flanders|1800214N, agency for innovation by Science and Technology in Flanders (IWT) through the SAFEPEDRUG project|IWT/SBO 130033, Eunice Kennedy Shriver National Institute of Child Health and Development|5T32HD087969, Eunice Kennedy Shriver National Institute of Child Health and Development|5U54HD090254)status: Publishe
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Neonatal drug therapy: The first frontier of therapeutics for children
No full textKnowledge about the safe and effective use of medicines in neonates has increased substantially but has resulted in few label changes. Drugs developed for use in adults are reshaped and tailored to specific neonatal indications. However, the use of drugs in neonates should not only mirror adult pharmacotherapy, but should be driven by their own specific needs. Therefore, building collaborative networks may assist to develop a newborn-driven research agenda addressing their clinical needs and diseases.sponsorship: Dr Karel Allegaert is supported by the Fund for Scientific Research, Flanders (fundamental clinical investigatorship 1800214N) and the research activities are further facilitated by the agency for innovation by Science and Technology in Flanders (IWT) through the SAFEPEDRUG project (IWT/SBO 130033). Dr John van den Anker is supported by the NIH (K24DA027992, R01HD048689, U54HD071601) and the European Commission (TINN (223614), TINN2 (260908), NEUROSIS (223060)). Special thanks goes to Dr Marc Pfister for designing Figure 4. (Fund for Scientific Research, Flanders|1800214N, agency for innovation by Science and Technology in Flanders (IWT)|IWT/SBO 130033, NIH|K24DA027992, NIH|R01HD048689, NIH|U54HD071601, European Commission|223614, European Commission|260908, European Commission|223060)status: Publishe
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Expanding “Communities and Collections” in the K-State Research Exchange (K-REx) to benefit the K-State Community and Beyond
No full textKansas State University has used its institutional repository, the K-State Research Exchange (K-REx), to store and share its first year experience program, K-State First, and notably its common reading program, K-State First Book. We have done so with the aim that the accessibility and preservation of these documents ensures program stability, promotes engagement with first year programming, and provides the ability to foster growth,educational opportunities, and community building outside of K-State. Moving away from research concentrated repositories and taking a more holistic approach to scholarship, especially when realizing the pedagogical significance of collaborative campus programming, institutions can showcase, discover, preserve, and grow programs that shape campus communities and engagement.
This session will provide an overview of K-REx and spotlight the digital archive of the university’s first year experience program and common reading program, K-State First Book. We will discuss the benefits and challenges to expanding the purview of your repositories. We talkthrough the types of materials we decide to host in our repository and why we share what we do. We will also provide recommendations on new ways to evaluate what belongs in institutional repositories and how this diversity can benefit your program, your institution, the community, and others
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