36 research outputs found
Possible Applications Of Judicial Precedent And Legal Consuetude In The Regulation Of Labor Disputes
No full textThe role of uzbek novators in political and economical change and the critical view of Fitrat`s in her “Debate” book
No full textThis article indicates the main features of literature in human beings life and enlights the history of Turkistan in XXcentury. The main issues of collapsing of three empires in Turkistan and the sorrowful days of Bukhara are explained by author in this material. Additionally, today`s some global problems are debated and reasoned in pieces of Fitrat`s book
APOE GENE ALLELE DISTRIBUTION AND ALZHEIMER’S DISEASE RISK IN THE KAZAKHSTANI POPULATION: A CASE-CONTROL STUDY
No full textPathology of Amyloid-β (Aβ) Peptide Peripheral Clearance in Alzheimer’s Disease
No full textAlthough Alzheimer’s disease (AD) is traditionally viewed as a central nervous system disorder driven by the cerebral accumulation of toxic beta-amyloid (Aβ) peptide, new interpretations of the amyloid cascade hypothesis have led to the recognition of the dynamic equilibrium in which Aβ resides and the importance of peripheral Aβ production and degradation in maintaining healthy Aβ levels. Our review sheds light on the critical role of peripheral organs, particularly the liver, in the metabolism and clearance of circulating Aβ. We explore the mechanisms of Aβ transport across the blood–brain barrier (BBB) via transport proteins such as LRP1 and P-glycoprotein. We also examine how peripheral clearance mechanisms, including enzymatic degradation and phagocytic activity, impact Aβ homeostasis. Our review also discusses potential therapeutic strategies targeting peripheral Aβ clearance pathways. By enhancing these pathways, we propose a novel approach to reducing cerebral Aβ burden, potentially slowing AD progression
Modern library and reading in multimedia environment
No full textThe article identifies the library's ability to stimulate reader activity in the context of the multimedia culture development. It also considers main changes in the library activities as an organizer of reading in multimedia culture including the increase of emphasis on readers, their subjectivity, interaction dialogue forms development, multimedia projects implementation, online services and digital resources introduction, education of readers on literate media behavior and text activity in the Internet. The author states that in the context of multimedia, library can become an active participant in overcoming information chaos, streamlining information flows, enhancing reading and also contribute to the development of inter-reader communication. The article concludes that it is necessary to prepare library specialists, tutors, ready to organize communication about books and reading in a real and virtual environment, network navigation, analysis of Internet resources, recognition of misinformation, and teaching readers various techniques of textual activity
A Review of the Energy Potential of Residual Biomass for Coincineration in Kazakhstan
No full textAlthough it has access to hydrocarbon reserves, Kazakhstan has developed a strategy for
the transition to a low-carbon economy, which should include the use of renewable energy sources.
In this framework, the use of biomass from waste could have the potential to reduce emissions from
traditionally fueled energy generation, as well as adding value to the generated waste, which also
improves waste management according to the principles of a circular economy. The analysis of the
resources and energy potential from residual biomass in Kazakhstan presents an annual production
of 37.26 106 tons of residual biomass, which could be capable of producing an energy potential
of 466.74 PJ/year, little more than half to the total production from all the installed power plants
in the country. Agricultural, animal and municipal solid waste are available to produce energy
in Kazakhstan based on combustion technologies; however, animal waste and agricultural are the
main potential sources with 61.02% and 38.34% of the theoretical total biomass potential energy
analyses, respectively. Considering that 80% of Kazakhstan’s electricity generation comes from
coal-fired plants, energy from agriculture could be co-fired for the gradual replacement of coal
with biomass in operational power plants, without substantially increasing costs or infrastructure
investments, thereby making the transition to a low-carbon economy and renewable energy sources
in the country easier.Government of the Republic of Kazakhstan
Ministry of Education and Science of the Republic of Kazakhstan AP14871168
AP14870834research group TEP-968 (Technologies for Circular Economy) of the University of Granad
MINIMIZATION OF TOXIC EMISSIONS DURING BURNING LOW-GRADE FUEL AT KAZAKHSTAN THERMAL POWER PLANT
No full textThis paper presents new results of computational experiments on the implementation of Overfire Air (OFA) technologies using an example of a combustion chamber of the BKZ-75 boiler of the Shakhtinskaya power plant (Shakhtinsk, Kazakhstan) burning high-ash Karaganda coal. The effect of mass air flow through special nozzles located above the burner level on the flow aerodynamics, temperature fields, concentration fields of carbon monoxide CO and nitrogen NO over the entire volume of the combustion chamber was studied. The studied characteristics were compared for various percentages of supplying additional air through OFA injectors: OFA is 0% (basic version), 10% and 18 %. It was shown that the installation of OFA injectors leads to a change in the field of the total velocity vector, temperature, and concentrations of carbon oxides and nitrogen. An increase in the percentage of air supplied through OFA injectors to 18% leads to a decrease in the concentrations of carbon monoxide CO by about 36% and nitrogen oxide NO by 25% compared with the base case. The obtained results will optimize the process of burning pulverized fuel in the combustion chamber of the BKZ-75 boiler, increase the efficiency of fuel burnout, reduce harmful emissions and introduce OFAtechnology at other coal-burning thermal power plants
Methodological Aspects of Studying the Reading of Modern Youth
No full textРукопись поступила в редакцию 31 июля 2018 г.В статье речь идет о методологических аспектах изучения чтения российской молодежи: обоснована необходимость формирования исследовательских подходов, связанных с трансформациями в книжном процессе, появлением новых дифференцирующих оснований взаимодействия с названной категорией читателей, необходимостью выявления стимулирующего или, напротив, угнетающего воздействия различных коммуникационных каналов. Представлены адекватные для нынешнего этапа развития цифровых технологий теоретические подходы исследования «Чтение российской молодежи в век цифровых технологий: стимулы и практики». Охарактеризованы базовые понятия исследования, показаны различия и эмпирические индикаторы практик чтения, практик читательской деятельности; рассмотрена значимая для современной молодежи система стимулов чтения на институциональном и неинституциональном уровнях. Сделаны выводы о необходимости разработки методов и приемов выявления практик чтения на основе произошедших в книжном процессе трансформаций, особенностей коммуникативного поведения и познавательной деятельности поколения зет, выявления действенных для него стимулов чтения и переосмысления деятельности институтов инфраструктуры чтения на основе субъект-субъектного взаимодействия с молодежью в реальном и сетевом пространствах.The article deals with the methodological aspects of studying reading to Russian youth: the necessity of adapting research approaches due to follwoing factors: transformations in the publishing industry; emergence of the new ways to ineract with varying categories of readers; necessity to identify stimulating or, conversely, depressing effects of various communication channels. The author describes theoretical approaches in the project “Reading of Russian youth in the age of digital technologies: incentives and practices”, which are more adequate for the current digital technologies. The basic concepts of the research are characterized, the differences and empirical indicators of reading practices are shown. The reading incentive system for non-institutional levels, which is signifi cant for today's youth, is considered. The author concludes that there is a need to develop methods and techniques for identifying reading practices based on the transformations that have occurred in the publishing industry, the characteristics of the communicative behavior and cognitive activity of the Z generation, identifying effective reading incentives and rethinking the activities of reading infrastructure institutions on the basis of subject-subject interaction with young people in real life and network spaces
Numerical investigation of heat and mass transfer processes in the combustion chamber of industrial power plant boiler. Part 1, Flow field, temperature distribution, chemical energy distribution
No full textIn the present paper, the furnace chamber of the BKZ-160 boiler ofAlmaty TPP-3 (Kazakhstan) has been calculated.
The thermal characteristics of the process were studied in the form of the distribution of temperature fields and
chemical energy, and the aerodynamics of the combustion chamber was also calculated. The type of fuel, its
elementary and fractional composition, exerts the greatest influence on the course of heat-mass exchange processes
and aerodynamics. The computational experiment was carried out with two models of particle size distribution: a
polydisperse fuel flame (the particle diameter varies from 10 to 120 μm) and monodisperse fuel flame (particle size
identical and equal to dp = 60 μm). Based on the results of the computational experiments, the main regularities in
the distribution of heat fluxes in the combustion chamber volume and flow aerodynamicswere obtained. It is shown
that the greatest thermal load falls on the central region of the walls of the combustion chamber and the location of
the burner devices, which is typical for both mono- and polydisperse fuel flames. The temperature data obtained
as a result of the computational experiment showed better convergence with the empirical data obtained directly
at TPP-3. Aerodynamics of the flow for the two selected models of particle size distribution has insignificant
differences, but how they affect other characteristics of the process is one of the following tasks in view of the
authors. It should be noted that the calculation of the polydisperse fuel flame takes much more calculation time
