1,022 research outputs found
The Case Management FoC Model
This OSF project hosts the original and evolving conceptualization of the Case Management FoC Model, developed by Alessio Rizzo and Antonio Valenti (Italy, 2025). The model integrates the Fundamentals of Care framework with advanced nurse-led case management, grounded in a situated, relational, and pragmatic epistemology.
The project includes three key components:
an early conceptual draft (wiki section),
the operational perioperative flowchart used in clinical testing.
The concept paper (separate file)
This public deposit establishes authorship, timestamp, and theoretical consistency prior to peer-reviewed publication. Reuse and citation are permitted with explicit attribution.
The Case Management FoC Model is a registered method of care delivery designed to implement the Case Management methodology through direct and indirect interventions by advanced practice nurses. This model is centered on the principles of the Fundamentals of Care, aiming to minimize missed nursing care in the areas defined by the Fundamentals of Care framework across various nursing care settings
From 2015 to 2025: how ATA guidelines reshape nuclear medicine practice in thyroid cancer
Imposte sui redditi degli intermediari finanziari non residenti operanti in Italia
La crescente attenzione da parte degli operatori alla corretta tassazione dei redditi prodotti in Italia da parte di istituti di credito non residenti, testimoniata anche dalle diverse risposte ad interpelli presentanti sul tema e rese note nel corso del biennio 2018/2019, è stata accentuata dalla recente campagna di controlli, messa in atto dall’Agenzia delle Entrate e dalla Guardia di Finanza. Diversi istituti di credito svizzeri e monegaschi operanti con clientela italiana hanno infatti ricevuto questionari ed inviti - basati anche sulle informazioni raccolte dalle diverse edizioni di voluntary disclosure - finalizzati a verificare il corretto adempimento degli obblighi tributari in Italia. Il contributo si propone di individuare, anche alla luce dei recenti indirizzi di prassi, gli obblighi tributari
verso l’Amministrazione finanziaria italiana di un intermediario non residente e privo di stabile organizzazione in Italia, analizzando in particolare le diverse fattispecie secondo la normativa tributaria italiana e la CDI tra Italia e Svizzera
Reliability of Mental Workload Index Assessed by EEG with Different Electrode Configurations and Signal Pre-Processing Pipelines
Background and Objective: Mental workload (MWL) is a relevant construct involved in all cognitively demanding activities, and its assessment is an important goal in many research fields. This paper aims at evaluating the reproducibility and sensitivity of MWL assessment from EEG signals considering the effects of different electrode configurations and pre-processing pipelines (PPPs). Methods: Thirteen young healthy adults were enrolled and were asked to perform 45 min of Simon’s task to elicit a cognitive demand. EEG data were collected using a 32-channel system with different electrode configurations (fronto-parietal; Fz and Pz; Cz) and analyzed using different PPPs, from the simplest bandpass filtering to the combination of filtering, Artifact Subspace Reconstruction (ASR) and Independent Component Analysis (ICA). The reproducibility of MWL indexes estimation and the sensitivity of their changes were assessed using Intraclass Correlation Coefficient and statistical analysis. Results: MWL assessed with different PPPs showed reliability ranging from good to very good in most of the electrode configurations (average consistency > 0.87 and average absolute agreement > 0.92). Larger fronto-parietal electrode configurations, albeit being more affected by the choice of PPPs, provide better sensitivity in the detection of MWL changes if compared to a single-electrode configuration (18 vs. 10 statistically significant differences detected, respectively). Conclusions: The most complex PPPs have been proven to ensure good reliability (>0.90) and sensitivity in all experimental conditions. In conclusion, we propose to use at least a two-electrode configuration (Fz and Pz) and complex PPPs including at least the ICA algorithm (even better including ASR) to mitigate artifacts and obtain reliable and sensitive MWL assessment during cognitive tasks
Absolute Configuration Assignment of (3-Phenyloxirane-2,2-diyl)bis(phenylmethanone) via Density Functioal Calculations of Optical Rotation and Vibrational Circular Dichroism
Pitfalls and artifacts in [18F]-FDG PET imaging in children with lymphoma
: Positron emission tomography/computed tomography (PET/CT) with 2-[fluorine-18]fluoro-2-deoxy-D-glucose ([18F]-FDG) is a well-established imaging tool in adult oncology and is increasingly utilized also in pediatric oncology due to its ability to combine functional and anatomic information, thereby enhancing diagnostic accuracy and improving patient management. However, [18F]-FDG uptake in children differs physiologically from adults, and this radiotracer is not tumor-specific, with uptake occurring in various benign conditions such as inflammation, infection, and trauma. Accurate interpretation of pediatric [18F]-FDG PET/CT requires comprehensive knowledge of the normal distribution of FDG in children, recognition of physiological variants, and awareness of common benign lesions and PET/CT-related artifacts. Misinterpretation can lead to unnecessary follow-up studies, suboptimal treatment decisions, and/or increased radiation exposure. This review discusses the typical patterns of physiologic [18F]-FDG uptake in children, common benign mimics of malignancy, and potential artifacts and pitfalls encountered in pediatric [18F]-FDG PET/CT imaging, focus especially on head and neck (lymph nodes), brown adipose tissue, bone marrow and thymus. By increasing familiarity with these patterns, this review aims to improve diagnostic confidence, reduce interpretive errors, and promote safer and more effective imaging practices in pediatric oncology
The link between nutritional status and outcomes in COVID-19 patients in ICU. Is obesity or sarcopenia the real problem?
Obesity is frequent among COVID-19 patients and data indicate that this condition is associated with poor outcomes. Nutritional status,was often assessed by the calculation of body mass index (BMI) classes, allowing to indicate the presence/absence of overweight or obesity . However, scanty information is available on body composition in COVID-19 pa-tients in ICU and on patient’s muscularity. In fact, most of the studies conducted in these patients indicate a high prevalence of increased adiposity that seems to be able to predict the severity of the disease. Obesity was shown to predict COVID-19 severity also among young patients. In ICU (not COVID-19 patients), recent evidences showed that low skeletal muscle mass as assessed by CT, was a risk factor for reduced survival in mechanically ventilated patients, revealing that BMI was not an independent predictor of mortality when muscularity was considered
Decentralization and fuel subsidies
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this recordThis paper explores the role of decentralization in explaining variation in fuel subsidies across countries. Using panel data over the period 1998-2008 and for 108 countries, it emerges that the effect of ‘decentralization’ (taken to be an increase in the number of government levels) broadly decreases both diesel and gasoline subsidies, with this effect being more pronounced when the level of political accountability is low. For developing countries, for which political accountability is low, decentralization decreases gasoline and diesel subsidies by at least 6.98% and 12.99%, respectively. For developed countries, for which political accountability is high, decentralization does not have any impact on both gasoline and diesel. What this evidence points to is that in developing economies, where voters are poorly informed and accountability is low, decentralization appears to be associated with lower fuel subsidies.Leonzio Rizzo thankfully acknowledges financial support from the Spanish Ministry of Economy and Competitiveness (ECO2012-37873) and also from FIR 2016
Cooperative ways of working: towards a Mediterranean research project
edited by Godfrey Baldacchino. Saviour Rizzo, Edward L. Zammit.; Includes bibliographical references.Source type: Print(0
Detection of cardiac neuroendocrine tumour metastases by somatostatin receptor PET/CT: a systematic review and meta-analysis
Cardiac neuroendocrine tumour metastases (CNTM) are rare, but advancements in molecular imaging including somatostatin receptor PET/CT (SSTR-PET/CT) could lead to a more frequent identification. The aim of this article is to perform a systematic review and meta-analysis on the detection of CNTM by SSTR-PET/CT.
A comprehensive literature search of studies on CNTM detected by SSTR-PET/CT was carried out. Three different bibliographic databases were screened (Cochrane library, PubMed/MEDLINE, EMBASE) until 20 August 2024. Two review authors independently selected the eligible original articles and performed the quality assessment and the data extraction. Main findings of eligible studies were summarized and a proportion meta-analysis on the prevalence of patients with CNTM among those with neuroendocrine neoplasm (NEN) performing SSTR-PET/CT was carried out using a random-effects model.
Ten articles reporting data on 163 patients with CNTM were included in the systematic review. SSTR was able to detect CNTM earlier compared to other radiological imaging techniques. Most patients with CNTM had other metastatic sites and CNTM were often asymptomatic. The meta-analysis of seven articles demonstrated a pooled prevalence of 1.5% (95% confidence interval: 1.0-1.9%) of patients with CNTM (n = 119) among those performing SSTR-PET/CT for NEN (n = 9,300). Moderate statistical heterogeneity was found (I 2 test: 62%).
Evidence-based data demonstrate that SSTR-PET/CT enables early and better detection of CNTM compared to other radiological imaging methods. CNTM are encountered with a pooled prevalence of 1.5% of NEN patients performing SSTR-PET/CT. Prospective and multicentric studies are warranted to better clarify the impact of CNTM detection by SSTR-PET/CT on overall survival and clinical decision-making in NEN patients
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