1,354,992 research outputs found
Effects of maternal heart sounds on pain and comfort during aspiration in preterm infants
No full textkucuk alemdar, dilek/0000-0002-7275-0666WOS: 000446279700007PubMed: 29345047AimThis study aimed to evaluate the effects of providing prerecorded maternal heart sounds on the level of pain and comfort that are experienced by preterm infants during aspiration. MethodsThis was a randomized controlled trial. Preterm infants (N = 62) who were receiving care or treatment at a neonatal intensive care unit were eligible for participation in this study. Infants in the intervention group (n = 32) were provided with prerecorded maternal heart sounds before, during, and after aspiration, whereas the infants in the control group (n = 30) received routine care. For the collection of the data, the Preterm Infant Information Form was used to record natal and postnatal information of the preterm infant, the Premature Infant Pain Profile, assessed the level of pain, and the Premature Infant Comfort Scale, assessed the level of comfort. ResultsThere was a significant difference observed between the groups' pain levels during aspiration; however, the difference was not significant before and after aspiration. Furthermore, there was a significant difference observed between the groups' comfort levels prior to aspiration before and during aspiration; however, the difference was not significant after aspiration. ConclusionIntervention with maternal heart sounds during aspiration effectively reduced pain and provided comfort to the premature infants
Alemdar Mustafa Paşa’nın devlet hayatı
No full text06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması, Düzenlenmesi ve Erişime Açılmasına İlişkin Yönerge” gereğince tam metin erişime açılmıştır.Alemdar Mustafa Paşa 1765 yılında Hotin'de doğdu. Hacı Hasan Ağa'nın oğludur. Babası gibi Yeniçeri Ocağı'na girmiştir. Daha sonra Tirsinikli İsmail Ağa'nın hizmetine girmiştir. Kısa sürede Efendisinin güvenini kazanıp, kabiliyeti sayesinde hızla yükselmiştir. Alemdar Mustafa'nın lakabı İsmail Efendisine bayraktarlık yapmasından ileri gelir.Alemdar Mustafa kazandığı başarılarla önce Hassa Silahşörü rütbesi (1799) daha sonra Kapıcıbaşılık rütbesini (1803) bir müddet sonra da Hezargrad âyanlığına tayin edilmiştir. Alemdar Mustafa, Tirsinikli İsmail'in ölümü üzerine onun yerine Ruscuk âyanı oldu (1806). Bu sırada başlayan Rusya savaşı sırasında Rumeli'de oluşan zafiyet dolayısıyla III. Selim tarafından Alemdar Mustafa'ya önce vezirlik rütbesi ve Silistre valiliği daha sonra Tuna Seraskerliği verilmiştir (Şubat 1807)Bu savaş sırasında tertiplenen Kabakçı Mustafa isyanı neticesinde III. Selim tahttan indirilip, Nizam-ı Cedit'e son verilip IV. Mustafa tahta çıkarılmıştır. Bu sırada İstanbul'da ve orduda Nizam-ı Cedit ricali avı başlamıştır. Bunun üzerine Ruscuk Yaranı denilen kişiler Alemdar Mustafa Paşa'ya sığınmışlardır. Daha sonra Alemdar Mustafa'yla anlaşan Ruscuk Yaranı III. Selim'i tekrar tahta çıkarmak için İstanbul'a gelmeyi başarmışlardır. Alemdar Mustafa İstanbul'a varmadan önce adamını gönderip Kabakçı Mustafa'yı öldürtmüştür.Kendisinin yerine Alemdar Mustafa'nın III. Selim'i tahta çıkaracağını anlayan IV. Mustafa, III. Selim ve II. Mahmud'un öldürülmeleri için emir vermiştir. III. Selim'i öldürtmüş ama II: Mahmud kurtulmayı başarmıştır. Padişah olan II. Mahmud, Alemdar'ı sadrazam yapmıştır. Sadrazam olan Alemdar Mustafa Paşa âyanları toplayarak Sened-i İttifak denen belgeyi oluşturmuş ve Sekban-ı Cedid denen orduyu kurmuştur. Daha sonra Yeniçeriler tarafından tertiplenen bir isyan sırasında kendi konağında sıkışan Alemdar Mustafa Paşa intihar ederek kendisiyle beraber 300-400 Yeniçeriyi de öldürmüştür.Anahtar Kelimeler: Alemdar Mustafa Paşa, III. Selim, IV. Mustafa, Kabakçı Mustafa, Sened-i İttifakAlemdar Mustafa Pasha was born in 1765 in Hotin. He was the son of Hacı Hasan Aga. Like his dad, He enrolled the janissaries, then entered the service of Tirsinikli İsmail Aga. In a short time, due to the confidence of his master, he increased his popularity rapidly. His Monikers (onun lakabı İsmail Efendisine bayraktarlık yapmasından ileri gelir)With his rank of successes, he was appointed Hassa Silahşörü (1799) then Kapıcıbaşılık rütbesi (1803) and then Hezargrad âyanlığı. Because of the death of Tirsinikli İsmail, Alemdar Mustafa became the Ruscuk âyanı instead of him (1806).Due to beginning of Russian war at this time, which had cawsed vulnerability in Rumeli, He gained the Grand vizier rütbesi, then was given the governship of Silistre, then was given Tuna Seraskerliği (February 1807).During this war, as a result of Kabakçı Mustafa Rebellion, III. Selim was downloaded from the throne and IV. Mustafa was ascended to the throne. For this time It had begun hunting both in İstanbul and army to Nizam-ı Cedid.As a resut, Ruscuk Yaranı achieved to come back İstanbul fort o ascend him (III. Selim) to the throne back. Alemdar Mustafa was killed Kabakçı Mustafa on his way. As IV. Mustafa understood, who would ascend the throne, III. Selim was killed by IV. Mustafa; but II. Mahmud was succeded to get rid of from him.The Sultan II. Mahmud made Grand vizier to him. The Grand Vizier Alemdar collected Âyans and created the document which was called Sened-i İttifak and and set up the Sekban-ı Cedid Army.Later, during a riot organized by janissaries, he committed suicide in his own mansionKeywords: Alemdar Mustafa Pasha, III. Selim, IV. Mustafa, Kabakçı Mustafa, Sened-i İttifa
Effects of Covering the Eyes versus Playing Intrauterine Sounds on Premature Infants' Pain and Physiological Parameters during Venipuncture
No full textkucuk alemdar, dilek/0000-0002-7275-0666WOS: 000416355100005PubMed: 28751136Background: There is a need to assess the impact of initiatives to reduce exposure to environmental light and sound in preterm infants undergoing painful interventions in neonatal intensive care units. Objectives: In this study, we aimed to identify the effect of covering the eyes and playing the intrauterine ambient sounds on premature infants' pain and physiological parameters during venipuncture. Methods: This was a randomized controlled trial. Ninety-four preterm infants were randomly divided into three groups: intrauterine sounds (n = 32), covered eyes (n = 32), and control (n = 30) groups. Data were collected on the Preterm Infant Information Form, Preterm Infant Follow-up Form, and Neonatal Infant Pain Scale (NIPS), used to assess pain. Results: A significant difference was found between the intervention and control groups' NIPS score after venipuncture, which was primarily due to covered eyes' group. No significant difference was found between the intervention and control groups' NIPS score during venipuncture. In addition, no significant difference was found between the intervention and control groups of infants physiological parameters before, during, and after venipuncture. The practice of covering preterm infants' eyes during venipuncture positively affected their pain scores after venipuncture. Clinical Implications: The effect of covering the eyes and playing the intrauterine ambient sounds in preterm infants may be recommended as simple, safe, and supportive stimuli that facilitate positive effects during painful procedures. (C) 2017 Elsevier Inc. All rights reserved
The use of the buzzy, jet lidokaine, bubble-blowing and aromatherapy for reducing pediatric pain, stress and fear associated with phlebotomy
No full textkucuk alemdar, dilek/0000-0002-7275-0666PubMed: 30711327Purpose: This study aimed to investigate the effects of the Buzzy, Jet lidokaine, bubble-blowing and inhalation aromatherapy with lavender essence on pain, stress and fear in children undergoing phlebotomy. Designs and methods: This study was a prospective, randomized controlled trial. The sample was comprised of children aged 5 to 10 years requiring blood tests. Children were assigned to five subgroups through randomization performed using a computer program: the Buzzy group (n = 39), Jet lidokaine group (n = 39), bubble-blowing group (n = 39), inhalation aromatherapy with lavender essence group (n = 39) and control group (n = 39). The children's levels of pain were evaluated and reported by the parents, observers and the children, who self-reported using the Oucher Pain Scale. The children's fear levels were assessed using the Children's Fear Scale, and salivary cortisol analysis was conducted to evaluate stress levels. Results: A significant difference was found between the intervention and control groups in terms of levels of pain during and after phlebotomy in favor of the Buzzy group (p < 0.05). There was a significant difference between the fear scores of the children in the intervention and control groups before phlebotomy (p < 0.05). This difference was found to be caused by the bubble-blowing method. There was a significant difference between intervention and control groups fear levels in favor of the Buzzy group during phlebotomy (p < 0.05). Practice implications: It is recommended that the Buzzy and bubble-blowing be used during phlebotomy in children to reduce the severity of their pain. (C) 2019 Elsevier Inc. All rights reserved.Scientific Research Projects Unit of Giresun University/Turkey [SAG-BAP-A-140316-88]The research was financed by the Scientific Research Projects Unit of Giresun University/Turkey (SAG-BAP-A-140316-88). The content has not been published or submitted for publication elsewhere. The study was presented as orally at the 1st International and 5th National Sivas Midwifery Congress on April 23-25, 2018 in Sivas, Turkey, where it received the "Award for the Best Oral Presentation". The authors thank the children and parents who agreed to participate in this study for their efforts and contribution
Solvability of the clamped Euler–Bernoulli beam equation
No full textHasanov, Alemdar (Dogus Author)In this study, solvability of the initial boundary value problem for general form Euler–Bernoulli beam equation which includes also moving point-loads is investigated. The complete proof of an existence and uniqueness properties of the weak solution of the considered equation with Dirichlet type boundary conditions is derived. The method used here is based on Galerkin approximation which is the main tool for the weak solution theory of linear evolution equations as well as in derivation of a priori estimate for the approximate solutions. All steps of the proposed technique are explained in detail
Fabrication of a novel bone ash-reinforced gelatin/alginate/hyaluronic acid composite film for controlled drug delivery
No full textIn this study, a novel pH-sensitive composite film with enhanced thermal and mechanical properties was prepared by the incorporation of bone ash at varying concentrations from 0 to 10 v.% into gelatin/sodium alginate/hyaluronic acid (Gel/SA/HyA) polymeric structure for colon-specific drug delivery system. Films were characterized by FT-IR, SEM, and XRD analyses. Thermal and mechanical performances of films were determined by DSC, TGA and universal mechanical tester, respectively. Results proved that thermal stability and mechanical properties of bone ash-reinforced composite films improved significantly with respect to that of neat Gel/SA/HyA film. Cytotoxicity assay for composite films was carried out by using L929 cells. Water uptake capacity of films was determined by swelling test. Herein, release experiments of 5-Fluorouracil (5-FU) were performed in two different solutions (pH 2.1 and 7.4). The results assured that Gel/SA/HyA film containing BA could be considered as a potential biomaterial for controlled drug delivery systems. (C) 2016 Elsevier Ltd. All rights reserved
Effect of recorded maternal voice, breast milk odor, and incubator cover on pain and comfort during peripheral cannulation in preterm infants
No full textWOS: 000429503300001PubMed: 29579482Purpose: This study was conducted to assess the effect of recorded maternal voice, breast milk odor, and incubator cover on the pain and comfort of preterm infants during peripheral cannulation. Methods: This study was a randomized controlled trial. The sample of the study included 136 preterm infants who met the case selection criteria. The infants were randomly assigned to different groups. Data collection tool: In the study, a recorded maternal voice was played to the maternal voice group. The breast milk odor group was exposed to the odor of breast milk. The incubator cover group was covered by using an incubator cover before, during, and after the peripheral cannulation procedure on the infants in the experimental group. Result While no difference was observed between the groups before the peripheral cannulation procedure in terms of the total Premature Infant Pain Profile (PIPP) scores, a significant difference existed between the PIPP scores during and after the procedure. This difference was due to the incubator cover group. Conclusion: Breast milk odor, recorded maternal voice, and incubator cover in preterm infants are recommended as simple, safe, and supportive stimuli that facilitate positive effects during painful procedures
Oxygen-Generating Photocrosslinkable Hydrogel
No full textProviding sufficient amount of oxygen to the cells is a critical issue since the lack of adequate oxygen leads to cell death and tissue necrosis. Therefore, there is a vital need to design and fabricate oxygen-generating biomaterials to mitigate hypoxia-induced cell death in engineered tissues. Here, we report the fabrication of an oxygen-generating hydrogel by incorporating calcium peroxide (CPO) into the methacrylated gelatin (GelMA) structure using photocrosslinking process. A sustainable release of oxygen could be provided from CPO-GelMA hydrogel over a period of 5 days under hypoxic conditions (1% O-2)
Styrenated urethane oil synthesis via CuAAC click chemistry approach
No full textIn this study, a novel route for the modification of sunflower oil-based partial triglycerides with styrene (St) was described. For this purpose, in the first step, copolymers of St and 4-chloromethyl styrene (P(St-co-CMS)) were synthesized by free radical polymerization (FRP) and controlled/living radical polymerization (nitroxide mediated radical polymerization (NMRP)) methods. In the second step, chloro groups of these samples were transformed into azido groups by using NaN3/DMF and then azido groups were coupled with propargyl alcohol to achieve hydroxyl functional polystyrene chain (PSt-OH) via Cu(I)-catalyzed 1,3-dipolar azide-alkyne cycloaddition (CuAAC) click chemistry approach. Finally, alcohol groups of PSt-OH and the partial glyceride (PG) were combined by the reaction with toluene 2,4-diisocyanate (TDI). As a result, styrenated urethane oil (PG-TDI-PSt) was obtained as an oil-based binder. The structures were determined by FT-IR, H-1 NMR and GPC analyses, and film properties of the products were examined according to the related standards. (PG-TDI-PSt) gave good film properties, and therefore could be considered as an applicable oil-based binder. (C) 2015 Elsevier B.V. All rights reserved
Effect of Smelling Amniotic Fluid on Comfort and Crying in Preterm Infants During Peripheral Cannulation: A Randomized Controlled Trial
No full textThe aim of the study was to investigate the effect of smelling amniotic fluid on comfort and duration of crying caused by peripheral cannulation in preterm infants. This was a randomized controlled trial. The study sample consisted of 80 preterm infants meeting the case selection criteria. The infants were randomly assigned to experimental and control group. Upon exclusion of some infants from the study, total number of infants in both groups was 61. The infants in the amniotic fluid group smelled amniotic fluid for 15 minutes before, during, and for 15 minutes after the ap-plication of peripheral cannulation, whereas the infants in the control group did not undergo any in-tervention other than routine care. The level of comfort was significantly higher and the duration of crying lower in the infants from the amniotic fluid group as compared with control group before, during and after the procedure. The intervention of smelling amniotic fluid was found to be an effective practice that could be used for reducing the length of crying and increase comfort in preterm infants undergoing peripheral cannulation
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