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Prognostic factors of the patients admitted to the hospital at the subacut period of STEMI
YÖK Tez No: 272444Amaç: Akut miyokard infarktüsü (AMİ), ciddi morbidite ve mortalite ile seyreden yaygın bir hastalıktır. Hastaların başvuru anındaki risk derecelendirilmesinin yapılması, uygulanacak medikal ve girişimsel tedavinin belirlenmesi açısından önemlidir. ST elevasyonlu miyokard infarktüsü (STEMI) tedavisinin en önemli aşaması hızlı damar reperfüzyonudur ve pek çok çalışmada reperfüzyon ne kadar erken sağlanırsa o kadar çok canlı miyokard dokusunun kurtarıldığı gösterilmiştir. Ancak subakut dönemde başvuran hastalarla ilgili halen süren iskemiye işaret eden klinik ve/veya elektrokardiyografik kanıt bulunmaması durumunda, perkutan koroner girişimin (PKG) semptomların başlamasının üzerinden 12 saatten daha uzun bir süre geçmiş hastalarda da yararlı olup olmadığı konusunda görüş birliği bulunmamaktadır. Bu çalışmada STEMI ile uyumlu semptomların başlamasından sonra subakut dönemde hastaneye başvuran hastalarda morbidite ve mortalite üzerine etkili olabilecek faktörlerin, girişimsel ve medikal tedavi seçenekleri ile ilgili önerilerin belirlenmesi hedeflenmiştir.Yöntem: Bu retrospektif çalışmaya subakut dönemde hastaneye başvurmuş 94 STEMI hastası (62 erkek, 32 bayan) dahil edilmiştir. Hastalar 29±27 ay süresince takip edilmiştir. Hastane içi dönemde ve takip süresince ölüm görülen ve hayatta kalan, takip döneminde major istenmeyen kardiyovasküler olay yaşayan ve yaşamayan hastaların klinik özellikleri ve laboratuvar değerleri birbirleri ile karşılaştırılmıştır.Bulgular: Ölen hastaların başvuru sırasındaki yaşı, Killip skoru, başvuru anında EKG'de ST elevasyon miktarı, kreatinin ve MPV değerleri yaşayanlardan anlamlı olarak daha yüksek iken ejeksiyon fraksiyonu ve hematokrit değerleri anlamlı olarak daha düşüktü. Ayrıca ölen hastalarda KKY öyküsü, hastane yatışında EKG'de atrial fibrilasyon ve geniş QRS varlığı anlamlı olarak daha fazlaydı. Hastane içi dönemde ölüm görülen hasta grubunda yaş, Killip skoru ve kreatinin değeri lojistik regresyon analizinde anlamlı mortalite belirteci olarak saptandı. Takip süresince PKG uygulanmış hasta grubunda ölüm ve major istenmeyen kardiyovasküler olay geçirme oranları daha düşük olarak tespit edildi.Sonuç: STEMI ile uyumlu semptomların başlamasından sonra subakut dönemde hastaneye başvuran hastalarda, başvuru anında morbidite ve mortalite üzerine etkili faktörlerin belirlenmesi, gerek hastane içi gerekse uzun dönem takip sonuçları ile ilgili öngörüde bulunmamıza ve hastalar için en uygun tedavi protokolünü belirlememize olanak sağlayabilir. Halen süren iskemiye işaret eden klinik ve/veya elektrokardiyografik kanıt bulunmayan hasta grubunda geç dönemde PKG uygulanması major kardiyovasküler istenmeyen olay yaşama ve ölüm görülme oranlarında azalma sağlayabilir.Background: Acute myokardial infarction (AMI) is a common disease that causes severe morbidity and mortality. Assesment of risk stratification at admission is important for deciding whether medical or interventional therapy is better. The most important step of the STEMI treatment is rapid reperfusion of arteries and it is shown in many studies that, sooner you get reperfusion more you get alive myocardial tissue. But it?s not clear whether percutaneus coronary intervention (PCI) is better for the patients who applied to hospital at subacute period and not have any clinic and/or electrocardiographic evidence for continued ischemia when more than 12 hours passed from onset of the symptoms. We aimed to determine the factors that may be responsible for morbidity and mortality at the time of admission and also interventional or medical treatment options in the patients who applied to hospital at subacute period after beginning of the STEMI concordant symptoms.Methods: 94 patients with subacute STEMI were included in this study. (62 male, 32 female) Their follow-up time is 29±27 months. The patients?, who died or lived and who had or not have major adverse cardiovascular events during in-hospital and out hospital follow up time, clinic and biochemical values were compared to each other.Results: Age, Killip score, ST elevation amount on admission ECG, creatinin and MPV values of the patients who died, were significantly higher than the patients who lived and their ejection fraction, hematocrit values were significantly lower. Also history of congestive cardiac failure, atrial fibrillation on ECG at admission and large QRS existance were significantly much more than the patients who survive. Killip score, age and creatinin were determined by logistics regression analysis to be significant mortality marker in the patients who died during in hospital follow up time. Major adverse cardiovascular events and death rate were found lower in the patients who underwent PCI during follow up time.Conclusions: Determination of the factors that may be responsible for morbidity and mortality at the time of admission in the patients who admitted to hospital at subacute period after beginning of the STEMI concordant symptoms, can help us to predict patients? in hospital and life time prognosis and to decide the most suitable therapy for the patients. Late percutaneus coronary intervention (PCI) may reduce major adverse cardiovascular events and death rate in the patients who not have any clinic and/or electrocardiographic evidence for continued ischemia
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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