1,722,191 research outputs found

    Zum Geleit. Introduzione alla tesi di Francesca Aldrighetti

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    Enorme il cammino compiuto nell’Europa occidentale dal 1952. Quella storia è parzialmente scritta negli Heimatjahrbücher del Landkreis Mainz-Bingen. A quei volumi ha voluto dedicare la propria attenzione Francesca Aldrighetti, che già nella scelta del tema della sua tesi di laurea, dava prova dell’europeismo da cui è animata. La sua sensibilità europeistica la porta a studiare una regione particolarmente ricca di storia e di cultura, il Landkreis Mainz-Bingen, che lei visita sfogliando appunto gli Heimatjahrbücher. Questa preziosa pubblicazione le racconta prima di tutto le tappe principali dell’integrazione europea con Verona, ma poi anche il proprio volto geofisico, la propria storia dalle origini al presente, come pure la vita economica, agraria e industriale. E’ un denso e prezioso lavoro quello di Francesca Aldrighetti, che meriterebbe una più ampia conoscenza proprio in Italia e in particolare nella provincia di Verona per dare più solide basi a un’amicizia tra i popoli che si nutre di storia e di cultura oltre che di contatti personali

    Earthquake dynamics from pseudotachylyte microstructure

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    Data Repository for the production of Figure 3 and Table 1 of the manuscript "Earthquake dynamics from pseudotachylyte microstructure" by Aldrighetti S., Pennacchioni G. and Di Toro G

    Metodi di Supply Network Design in presenza di disruptions

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    Enterprises worldwide are facing significant challenges from the growing competition and the destabilising effects of climate, disease, and other external perils. Supply chain (SC) networks become more and more complex and widely geographical extended. SCs are exposed to a broad range of uncertainties, some of which may cause disruptions in the network. Neglecting this kind of risks may lead to adverse consequences such as negative financial effects, higher transportation costs, order delays, inventory shortages and loss of market shares. Disruption management is, therefore drawing significant attention from both academia and industry. The frequent disruption events that have been continuously increasing over recent years have clearly shown the key role of supply chain management as a critical capability to navigate such risk successfully, with the aim to design robust and resilient logistics network to help firms maintain and enhance their competitive advantages as they encounter environmental turbulence. To hedge against SC disruptions, a well-designed and reliable network that performs efficiently in normal situation and resiliently during unstable conditions is a top priority. This dissertation investigates how supply network design procedure should adapt due to disruption risks consideration. After an extensive analysis of the literature, a new mathematical model for the design and planning of three-echelon resilient SCs is proposed. Distinctively, a combination of proactive and reactive resilience actions were considered with the objective to analyse the effectiveness of adopting mitigation and contingency activities to efficiently plan for redundancies and recovery actions. This research work allowed to identify important relations between disruption duration/magnitude and efficiency of preparedness and adaptation strategies. The outcome of this research can be instructive for SC managers when deciding on investment in redundancy allocation and on efficient use of this redundancy at recovery stages and preparedness strategy.Enterprises worldwide are facing significant challenges from the growing competition and the destabilising effects of climate, disease, and other external perils. Supply chain (SC) networks become more and more complex and widely geographical extended. SCs are exposed to a broad range of uncertainties, some of which may cause disruptions in the network. Neglecting this kind of risks may lead to adverse consequences such as negative financial effects, higher transportation costs, order delays, inventory shortages and loss of market shares. Disruption management is, therefore drawing significant attention from both academia and industry. The frequent disruption events that have been continuously increasing over recent years have clearly shown the key role of supply chain management as a critical capability to navigate such risk successfully, with the aim to design robust and resilient logistics network to help firms maintain and enhance their competitive advantages as they encounter environmental turbulence. To hedge against SC disruptions, a well-designed and reliable network that performs efficiently in normal situation and resiliently during unstable conditions is a top priority. This dissertation investigates how supply network design procedure should adapt due to disruption risks consideration. After an extensive analysis of the literature, a new mathematical model for the design and planning of three-echelon resilient SCs is proposed. Distinctively, a combination of proactive and reactive resilience actions were considered with the objective to analyse the effectiveness of adopting mitigation and contingency activities to efficiently plan for redundancies and recovery actions. This research work allowed to identify important relations between disruption duration/magnitude and efficiency of preparedness and adaptation strategies. The outcome of this research can be instructive for SC managers when deciding on investment in redundancy allocation and on efficient use of this redundancy at recovery stages and preparedness strategy

    Correction to: Diffusion, outcomes and implementation of minimally invasive liver surgery: a snapshot from the I Go MILS (Italian Group of Minimally Invasive Liver Surgery) Registry

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    A technical error led to incorrect rendering of the author group in this article. The correct authorship is as follows: Luca Aldrighetti, Francesca Ratti, Umberto Cillo, Alessandro Ferrero, Giuseppe Maria Ettorre, Alfredo Guglielmi, Felice Giuliante, Fulvio Calise on behalf of the Italian Group of Minimally Invasive Liver Surgery (I GO MILS) The collaborators are: Raffaele Dalla Valle, AOU Parma, Parma; Vincenzo Mazzaferro, Istituto Nazionale Tumori, Milano; Elio Jovine, Ospedale Maggiore, Bologna; Luciano Gregorio De Carlis, Ospedale Niguarda Ca’ Granda, Milano; Ugo Boggi, AOU Pisana, Pisa; Salvatore Gruttadauria, ISMETT, Palermo; Fabrizio Di Benedetto, AOU Policlinico di Modena, Modena; Paolo Reggiani, Ospedale Maggiore Policlinico, Milano; Stefano Berti, Ospedale Civile S.Andrea, La Spezia; Graziano Ceccarelli, Ospedale San Donato, Arezzo; Leonardo Vincenti, AOU Consorziale Policlinico, Bari; Giulio Belli, Ospedale SM Loreto Nuovo, Napoli; Guido Torzilli, Istituto Clinico Humanitas, Rozzano; Fausto Zamboni, Ospedale Brotzu, Cagliari; Andrea Coratti, AOU Careggi, Firenze; Pietro Mezzatesta, Casa di Cura La Maddalena, Palermo; Roberto Santambrogio, AO San Paolo, Milano; Giuseppe Navarra, AOU Policlinico G. Martino, Messina; Antonio Giuliani, AO R.N. Cardarelli, Napoli; Antonio Daniele Pinna, Policlinico Sant’Orsola Malpighi, Bologna; Amilcare Parisi, AO Santa Maria di Terni, Terni; Michele Colledan, AO Papa Giovanni XXIII, Bergamo; Abdallah Slim, AO Desio e Vimercate, Vimercate; Adelmo Antonucci, Policlinico di Monza, Monza; Gian Luca Grazi, Istituto Nazionale Tumori Regina Elena, Roma; Antonio Frena, Ospedale Centrale, Bolzano; Giovanni Sgroi, AO Treviglio-Caravaggio, Treviglio; Alberto Brolese, Ospedale S.Chiara, Trento; Luca Morelli, AOU Pisana, Pisa; Antonio Floridi, AO Ospedale Maggiore, Crema; Alberto Patriti, Ospedale San Matteo degli Infermi, Spoleto; Luigi Veneroni, Ospedale Infermi AUSL Romagna, Rimini; Giorgio Ercolani, Ospedale Morgagni Pierantoni, Forlì; Luigi Boni, AOU Fondazione Macchi, Varese; Pietro Maida, Ospedale Villa Betania, Napoli; Guido Griseri, Ospedale San Paolo, Savona; Andrea Percivale, Ospedale Santa Corona, Pietraligure; Marco Filauro, AO Galliera, Genova; Silvio Guerriero, Ospedale San Martino, Belluno; Giuseppe Tisone, Policlinico Tor Vergata, Roma; Raffaele Romito, AOU Maggiore della Carità, Novara; Umberto Tedeschi, AOU Integrata Verona, Verona; Giuseppe Zimmitti, Fondazione Poliambulanza, Brescia

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Long term central venous access in oncology: Who, why, when?

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    Long Term Central Venous Catheters (LTCVC) are widely used for administration of chemotherapy, blood products, parenteral nutrition, analgesics, antibiotics. Nevertheless, indications for the placement of LTCVC are not well defined in cancer patients and specific guidelines are still missing, so that the need for placement of an LTCVC is often based on the lack of alternative routes for intravenous treatments secondary to the severe loss of peripheral veins by recurrent and/or prolonged infusion of toxic drugs, such as chemotherapy and parenteral nutrition. This approach is the main factor behind several local complications (phlebitis, extravasation of drugs with ulcers or necrosis, pain) as well as an unacceptable delay in the chemotherapy schedule. The need for an LTCVC has to be considered during the first patient assessment while defining the plan of therapy and placement has to be planned prior to therapy administration. The pre-therapy placement of LTCVC is mandatory if one of the following criteria is present: low availability of peripheral venous accesses, schedules of chemotherapy by continuous infusion or by bolus with vesicant drugs with possible local toxicity with or without extravasation, high-dose chemotherapy, multiple infusion requirements (i.e. chemotherapy plus high volumes of intravenous fluids plus blood products), total parenteral nutrition. Pre-therapy placement of LTCVC is suggested for adjuvant chemotherapy in patients at high risk for early tumour recurrence, low patient compliance to multiple venipunctures, domiciliary treatment. In all other conditions, pre-therapy placement of LTCVC is not indicated but infusion routes should be carefully evaluated during the course of therapy so that the need for an LTCVC may be detected before treatment has to be interrupted for lack of vascular access
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